TY - JOUR AU - Muanprom, Supattra AU - Putthipat, Nongwipa AU - Kiatsirirote, Kritirat PY - 2022/03/31 Y2 - 2024/03/29 TI - Evaluation of fluoride release and recharge of composite resin containing surface pre-reacted glass ionomer fillers (Beautifill II) JF - Journal of The Department of Medical Services JA - J DMS VL - 47 IS - 1 SE - Original Article DO - UR - https://he02.tci-thaijo.org/index.php/JDMS/article/view/251665 SP - 72-79 AB - <p><strong>Background: </strong>Biomaterials have been developed with the ability of fluoride release for caries prevention. A modified resin composite with surface pre-reacted glass ionomer (S-PRG) fillers would overcome disadvantages of glass-ionomer cement in term of mechanical properties while improve bio-functional characteristics of the resin of fluoride release like glass ionomer cement.<strong>Objective</strong>: This study aimed to evaluate the effectiveness of fluoride release and recharge from a modified resin composite with surface pre-reacted glass ionomer fillers.<strong>Methods</strong>: Thirty disc-shaped experimental specimens (8X2 mm in diameter, n=10/group) were prepared from 3 types of materials; resin composite (Filtek™), resin composite containing S-PRG filler (Beautifill II), and glass ionomer cement (Fuji II <sup>® </sup>LC). All specimens were kept in dry condition at 37C<sup>๐</sup> for 1 hours before soaking in 3 ml of deionized water for 12 hours. Then, all specimens were recharged with 1000 ppm NaF solution for 12 hours before rinsed and soaked in 3 ml of deionized water for a further 24 hours. Amount of fluoride was measured daily for an initial release over 7 days and repeated for 10 cycles of the recharge. The mean fluoride concentration per surface area (μg/cm<sup>2</sup>) was calculated and analyzed using repeated measure ANOVA at <em>P&lt;0.05,</em> followed by Turkey’s HSD multiple comparison test.<strong>Result: </strong>Fluoride released from  the resin composite containing S-PRG filler showed a significantly higher level of fluoride than that of resin composite but significantly lesser than conventional glass ionomer cement entire periods of  initial release and after recharging with 1000 ppm NaF.<strong>Conclusion:</strong> A modified resin composite with S-PRG filler had capability of initial fluoride release and sustained release after recharge with fluoride regimen. Despite, lower level of fluoride release than conventional glass ionomer cement, it could act as a fluoride reservoir for prevention of caries in oral cavity.</p> ER -