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This randomized controlled trial aimed to examine the effects of a nurse-led, self-management, enhancement program used as an intervention for self-management behaviors, disease control, and quality of life among Thais with chronic kidney disease, pre-dialysis. Purposive sampling was used to recruit 120 participants, of whom 60 were equally diagnosed with chronic kidney disease at stages 3 and 4. Participants were randomly assigned to either the experimental (n=60) or control group (n=60). The experimental group received the 6-week intervention in addition to usual care, while the control group received only usual care. Outcome variables included self-management behaviors, systolic blood pressure, diastolic blood pressure, HbA1c, serum creatinine, and quality of life. Data were collected through self-reported questionnaires, blood pressure measurements, and laboratory procedures, at baseline, 4 weeks, 12 weeks, and 24 weeks after participation in the program. Data were analyzed using descriptive statistics, paired t-test, and independent t-test. Results revealed that after program completion and compared to the control group, at 4 weeks the experimental group had significantly better self-management behaviors; at 12 weeks, lower systolic blood pressure, diastolic blood pressure, and HbA1c; and, at 24 weeks, better quality of life. However, there was no significant difference in serum creatinine between groups at 24 weeks. Findings indicate the program improved health outcomes. Hence, self-management enhancement should be incorporated into nursing practice for individuals with chronic kidney disease at pre-dialysis stage.
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