Region 11 Medical Journal

Prevalence of Post COVID-19 condition in SARS-Cov-2 infection patients at 3 months follow up in Chaiya Hospital, Surat Thani

Ketsarin Bunrod — 2024-02-29

Background: Post-acute COVID Syndrome (Long COVID) is defined as when a patient has recovered from the acute phase of the coronavirus disease 2019 but still has physical and/or mental symptoms which occur at 12 weeks after infection.

Objective: This study aimed to explore the prevalence and factors associated with Long COVID.

Method: Analytical cross-sectional research was conducted in patient databased recorded in HOSxP at Chaiya Hospital, Surat-Thani from January 2021-August 2022.

Results: The prevalence of symptoms after 12 weeks of acute covid-19 infection was dyspnea (4 %), insomnia (2 %), dry cough (1.3%), fatigue (1.3%). and 9.1 % had at least one symptom of long covid at 12 weeks follow up. It was found that prevalence of long covid occurred in female more than male (11.9% vs 5.0% p-value = .042).Patients with underlying Diabetes millitus are more likely to develop symptoms than others NCD (Hypertension, old myocardial infarction, stroke, primary hyperthyroid) at 20.7% vs 7.9 % (p-value = .023).History of covid-19 vaccination can decrease symptom of long covid by only 1.1% of vaccinated patients got long covid at 12 weeks follow- up (p-value = .002). And finally we found that old age patients (40-59 years and 59 years and over) will develop more long covid symptom than patient age 18-39 years (p=.001,p=.044).

Conclusion: The prevalence of Long COVID with at least one residual symptom was noticed. Common symptoms included dyspnea, insomnia, dry cough and fatigue. Factors associated with Long COVID syndrome were sex, in which female were found more than male, Diabetic patients and older age will develop more long covid symptom and the most important analysis data is covid vaccination can decrease long covid symptom. According to the study results, patients infected with the coronavirus 2019 suffer from Long-COVID-19. The public health system should provide surveillance, screening, and monitoring of patient symptoms, advise on observing symptoms after hospital discharged, and provide medical services.

Effectiveness of caring for type 2 diabetic patients to diabetes remission with intensive lifestyle modification, Suratthani Province

Pichit Suksabai — 2024-01-31

Background: Currently, there is treatment for patients with type 2 diabetes to enter a phase of diabetes remission, called diabetes remission, with the aim of being able to control blood sugar to a level below the diabetes diagnosis criteria without using medication to control it. Reduce sugar levels This will improve the patient's quality of life and reduce the chance of complications.

Objectives: To study the effectiveness of caring for type 2 diabetic patients (body mass index, waist circumference, and Hemoglobin A1C: HbA1C), ability to control blood sugar, reducing medication and stopping medication with intensive lifestyle modification and satisfaction with medical treatment with intensive lifestyle modification.

Method: This research was a quasi-experimental research. The study samples were type 2 diabetic patients, aged 18 years and over, and came to treatment at Ban Na San Hospital, Kanchanadit Hospital, Ban Ta Khun Hospital, Ban Na Derm Hospital and Chaiburi Hospital (40 people each), blood sugar level before the study (HbA1c) of 7 mg% or more, amount 200 people, which were divided into experimental group and comparison group, 100 people per group. Research tools were guidelines of medical care for diabetic patients with intensive lifestyle modification and traditional lifestyle modification, health status record form, satisfaction questionnaire with intensive lifestyle modification, and health assessment tools. Data was analyzed by descriptive statistic, Chi-square test, Independent t-test and Paired sample t-test.

Results: The results after intensive lifestyle modification found that diabetic patients had decrease in body mass index, waist circumference, and HbA1c after the 3 months and 6 months study by statistical significant (p-value < 0.001), and had decrease in HbA1c after 3 months and 6 months of study more than the comparison group, decrease in body mass index, waist circumference after 6 months of study more than the comparison group by statistical significant (p-value < 0.01). After the 3 months study, diabetic patients were able to control their blood sugar at 39.0%, reduce their diabetes medications at 46.0%, but no one was able to stop their diabetes medications. After 6 months of study, they were able to control their blood sugar at 91.0%, reduce diabetes medication at 57.0% and stop medication at 16.0%. However, most of diabetic patients were satisfied with intensive lifestyle modification at high level, 93.0%.

Conclusion: This medical care by intensive lifestyle modification can be used to care type 2 diabetic patients, and should be extended to use in various hospitals in the future.

Relationship between HPV Typing Non 16/18 and the results of the Liquid Base Cytology test of Thai women undergoing cervical cancer screening

Wannida Saisin — 2024-02-29

Background: Infection with papillomavirus (HPV), encompassing types 16/18 as well as non 16/18 variants, presents a heightened susceptivity to the development of cervical cancer. It is imperative to underscore that the detection of non 16/18 HPV strains necessitates confirmation through Liquid Base Cytology screening methodology.

Objective: This retrospective study aimed to study the relationship between HPV Type Non 16/18 and the results of the Liquid Base Cytology test of Thai women undergoing cervical cancer screening.

Method: The purposive sampling technique was used for selecting a Thai woman undergoing cervical cancer screening at Sichon Hospital, Nakhon Si Thammarat Province, and has the HPV DNA Test results Typing Non 16/18 for the fiscal year 2022, numbering 144 cases. Data were analyzed using descriptive statistics, finding frequencies, and percentages, and finding relationships using chi-square statistics and Fisher extract tests.

Results: The results of the study found that Thai women who went for cervical cancer screening and had HPV DNA Test results as Type Non 16/18 with an average age of 46.11 ± 7.55 years, with an age range of 40-49 years (40.3%), HPV Multiple type 22 cases (15.3%), single type 122 cases (84.7%). The first 3 most common HPV types were 58 (23.6%), 52 (16%), and 51 (14.6%) with 31 (14.6%) having test results by the normal liquid base cytology method, including Negative for Intraepithelial Lesion or malignancy for 79 cases (54.9%) and positive test results for 65 cases, accounting for 45.1% of the number of positive test results. Abnormalities were found in 31 cases of LSIL (21.5%), ASC in 28 cases (19.4%), and HSIL in 6 cases (4.2%), and found that women with HPV typing Type Non 16/18 and having an age range of 50-59 years have the most NILM test results (46.8 %), while those aged 40-49 years have the most test results in the >ASC-US group (44.6%), which is a significant difference. Statistically significant (P-value = 0.048). The HPV Non 16/18 are not related to the Liquid Base Cytology test results (P-value = 0.048)

Conclusion: HPV DNA Test results as Type Non 16/18 are not related to the Liquid Base Cytology test results in Thai women who went for cervical cancer screening. However cervical cancer screening should be promoted to high-risk groups. Focusing on all high-risk HPV Types Non 16/18. Moreover, using such information to manage the health system in order to reduce the risks of the disease as well as increase the chance of treatment in the early stages. Consequently, the treatment will be effective. This is an important step in increasing quality of life and effectively reducing the burden of medical expenses on society.