@article{Suriyawongkul_Gosrisirikul_Choonhaklai_Thaidumrong_Pumpaisanchai_Wongwattanasatien_Sindhubodee_Huabkong_2021, title={Renal function of bladder cancer patients after urinary diversion by ileal conduit in Rajavithi Hospital}, volume={42}, url={https://he02.tci-thaijo.org/index.php/TJU/article/view/241379}, DOI={10.52786/isu.a.20}, abstractNote={<div class="page" title="Page 1"> <div class="layoutArea"> <div class="column"> <p><strong>Objectives:</strong> Our objectives were to evaluate the long-term renal function after radical cystectomy (RC) and ileal conduit diversion (ICD) and to analyze year-by-year the estimated glomerular filtration rate (eGFR) and morphologic upper urinary tract changes.</p> <p><strong>Materials and Methods:</strong> We retrospectively identified 214 patients who had undergone RC and ICD from 2012 to 2018, with regular postoperative follow-up visits. The eGFR was calculated using the Modification of Diet in Renal Disease equation at baseline and during follow-up. A renal function decrease was defined as a greater than 10 mL/min/1.73 m2 reduction in the estimated glomerular filtration rate.</p> <p><strong>Results:</strong> The median follow-up period after RC was 24 months (range, 6-60 months). The median eGFR decreased from 64 mL/min/1.73 m2 (range, 9-125 mL/min/1.73 m2) to 61.5 mL/min/1.73 m2 (range, 8-125 mL/min/1.73 m2). A decline in renal function occurred during the first postoperative years (2.74 mL/ min/1.73 m2 and 3.95 mL/min/1.73 m2 in the first and second year, respectively), with a slight decrease in the subsequent years. The strongest predictor of an eGFR decline was CKD stage 1 or 2 (> 60 mL/min/1.73 m2). Urinary obstruction was diagnosed in 6 patients (2.8%). Among the patients who underwent prompt interventional treatment, we did not find any association with the eGFR decline.</p> <p><strong>Conclusion:</strong> Patients with urinary ICD have a lifelong risk of chronic kidney disease. Regular monitoring of renal function and the morphologic upper urinary tract will permit early diagnosis and treatment of modifiable factors, avoiding irreversible kidney damage.</p> </div> </div> </div>}, number={1}, journal={Insight Urology}, author={Suriyawongkul, Sittichon and Gosrisirikul, Chawawat and Choonhaklai, Vorapot and Thaidumrong, Tanet and Pumpaisanchai, Somkiat and Wongwattanasatien, Nattapong and Sindhubodee, Sermsin and Huabkong, Matchima}, year={2021}, month={Jun.}, pages={34–39} }