The THAI Journal of OPHTHALMOLOGY

Success rate of pneumatic retinopexy in Mettapracharak hospital

2024-02-15T08:36:29+07:00

Objective: To assess the effectiveness of pneumatic retinopexy as a therapeutic approach for the management of rhegmatogenous retinal detachment(RRD) at Metta Pracharak Hospital. Additionally, the study seeks to identify the various factors that may impact the overall success rate of pneumatic retinopexy(PnR) surgery.

Design: Retrospective medical chart review.

Participants: Patient with primary RRD treated between September 2019 and august 2022 at Metta Pracharak hospital Thailand.

Methods: Medical records of all cases with primary RRD who underwent PnR with a follow-up period up to 3 months were included for analysis.

Results: data pertaining to 125 patients in our analysis. 76.0% (95/125), 69.6% (87/125), 65.6% (82/125) and 63.2% (79/125) of patients who followed up at 1 week 1,2, and 3 months, respectively, had primary anatomic reattachment. A total of 36.8% (46/125) of patients did not reattach with the initial PnR or re-detached in the early post-procedure period (3 months). Phakic lens status and preoperative BCVA better than 20/400 were significant predictor of PnR success at 3 months in a multivariate logistic regression analysis (P = 0.004) (P = 0.011).

Conclusion: The evidence from this study demonstrates a satisfactory treatment outcome for primary rhegmatogenous retinal detachment using pneumatic retinopexy at Metta Pracharak Hospital. and most patients experience improved vision compared to before the surgery.

Comparison of Refractive Changes Between Hang-Back and Conventional Muscle Recession in Patients with Horizontal Strabismus

2024-07-17T15:24:05+07:00

Objective: To compare refractive changes after horizontal strabismus surgery between conventional and hangback
techniques.

Methods: The patients with horizontal strabismus were divided into two groups: one group received the
conventional technique, and the other received the hang-back technique. Parameters affecting refractive changes were
measured. These measurements were taken three times after surgery, at 1 week, 1 month, and 3 months.

Results: A total of 32 eyes from 21 participants were examined, 16 eyes in each group: 11 participants using the
conventional technique and 10 participants using the hang-back technique. Two pediatric ophthalmologists performed
surgeries at Rajavithi Hospital using the same standard table of surgical dosage. Preoperatively, the mean spherical
equivalent (SE) in the conventional group was –1.69 ± 1.75 D, whereas the hang-back group had a mean SE of –1.218
± 1.44 D (P value = 0.162). The mean corneal astigmatism in the conventional group was –1.13 ± 0.69 D, compared
to –1.13 ± 0.63 D in the hang-back group (P value = 0.253). After 3 months of follow-up, the average SE in the
conventional group was –1.92+2.28 D. However, the hang-back group had –1.40 ± 1.67 D (P value = 0.463). The mean
corneal astigmatism in the conventional group was –1.33 ± 0.77 D, compared to –1.28 ± 0.78 D in the hang-back group
(P value = 0.856).

Conclusion: No statistically significant differences in the refractive error after horizontal strabismus surgery
were observed between the conventional and hang-back surgery groups after the 3-month follow-up.

The Effect of Inhalation Aromatherapy with Lavender Essential Oil in Patients Undergoing Cataract Surgery– A Randomized Control Trial

2024-07-17T15:42:20+07:00

Cataract is a common eye disease that causes blindness in millions of people worldwide. While phacoemulsification
can restore vision, anxiety and fear of pain can burden patients. This study investigated whether inhaling a blend of lavender
and menthol (Laventhol) aromatherapy could reduce anxiety and pain in patients undergoing cataract surgery.

Methods: In this single-blinded, randomized controlled trial, 89 patients undergoing cataract surgery were assigned
to either the aromatherapy group (n = 44) or the control group (n = 45). The aromatherapy group received two drops
of Laventhol essential oil applied to their face masks 10 minutes prior to the surgery, while the control group received
a normal saline solution. Anxiety and pain levels were measured before and afterwards.

Results: The Aromatherapy group exhibits statistically significant difference in postoperative and preoperative
anxiety score compared to the control group (mean STAI difference ± 2SD aromatherapy = -9.95 ± 10.80 vs normal
saline = -1.82 ± 7.95, p-value < 0.001*). Notably, self-assessment pain scores (SAPS) difference is significantly lower
in aromatherapy group compared to normal saline group (mean Pain Score difference aromatherapy = 0.25 ± 2.52 vs
normal saline = 2.34 ± 2.10, p-value < 0.001*). Importantly, no notable adverse events were reported in either group.

Conclusion: Laventhol aromatherapy effectively reduced anxiety and pain in patients undergoing cataract surgery.
This safe and non-invasive approach may improve the surgical experience and quality of life for cataract patients
worldwide.

A Study of The Relationship Between Citation Frequency and Journal Quartile Score of International Research Publications of Department of Ophthalmology, Faculty of Medicine Siriraj Hospital From 2017 to 2022

2023-12-22T16:01:29+07:00

Objective: To study the number of international research publications and citation frequency, analyze the relationship between the citation frequency and the Journal quartile score at different levels, and study trends in publications of the Department of Ophthalmology, Faculty of Medicine Siriraj Hospital from 2017 to 2022. To analyze the relationship of other indicators journal's that affect journal quality.

Methods: The international research publications of the Department of Ophthalmology, Faculty of Medicine Siriraj Hospital between 2017-2022 from the Scopus database were collected, including the number of articles, titles, authors, journal name, year of publication, type of article, type of access, and citation frequency. Next, collect the data from the Scimago Journal & Country Rank (SJR) database, including the journal quartile score (Q), subject area and category, coverage, country, SJR value, and the h-index of the journal. Then, the Journal Impact factors (JIF) from the Journal Citation Reports (JCR) database were collected. The number of citations will be retrieved on December 25, 2022, and analyzed by descriptive statistics. The data were compared and presented as frequency, percentage, and proportion. A study of relationships of other indicators of journal analyzed by Spearman's rank correlation statistics in case the data are non-normal distribution.

Result: The international research publications of the Department of Ophthalmology, Faculty of Medicine Siriraj Hospital from 2017 to 2022 were 177 articles. Most of the articles had published in 2022 (39 Articles). The total citation frequencies of research publications from 2017-2022 were 1,480 times. In 2017 had the highest citation frequency (697 times), and the Q1 journals were the highest citation frequency (1,184 times). A study of the correlation of other indicators in the journal data revealed that the relationship between SJR value and h-index of the journal (r=.773, p<.01) and the relationship between SJR value and impact factor (r=.773, p<.01) were a strong positive correlation, which was statistically significant.

Conclusion: International research publications of the Department of Ophthalmology Faculty of Medicine Siriraj Hospital from 2017-2022, most of the research publications were published in the first quartile journal (Q1 is the highest quartile), and we found that Q1 Journals were the highest number of citations and number of citations per document. On the other hand, Q4 journals were the lowest number of citations per document. Therefore, selecting the appropriate journal for publishing research articles are essential to increase the chances of receiving citation frequency. Researchers should publish their research articles in Q1 journals because they are level as high-quality journals indicating the quality and excellence of research publications. Furthermore, a high number of citations in research publications would not only show the quality and reliability of the research but also demonstrate the expertise of the researcher and the institution.

Biosimilars in Ophthalmology

2024-07-17T16:22:21+07:00

ยาชีววัตถุ เรียกในภาษาอังกฤษว่า Biopharmaceuticals หรือ biological medical products ซึ่งมักเรียกกันสั้น ๆ ว่า biologics หมายถึง ผลิตภัณฑ์ยาที่ผลิตใน สกัดจาก หรือกึ่งสังเคราะห์ (semisynthetic) จากแหล่งกำเนิดทางชีววิทยา¹ องค์การอนามัยโลกอธิบายว่ายาชีววัตถุ หมายถึง ยาซึ่งสร้างขึ้น และทำให้บริสุทธิ์จากการเพาะเลี้ยงเซลล์ ได้แก่ แบคทีเรีย ยีสต์ หรือเซลล์ของพืชหรือสัตว์ ซึ่งเป็นการผลิตในระดับใหญ่ (large scale)²ยาในกลุ่มนี้ได้แก่ วัคซีน สารกระตุ้นภูมิคุ้มกัน (allergen) ผลิตภัณฑ์จากเลือด จากเซลล์ รวมทั้งการบำบัดด้วยเซลล์ (cell therapy) การบ􀄞ำบัดด้วยพันธุกรรม (gene therapy)
เป็นต้น ยาชีววัตถุอาจประกอบด้วยน􀄞้ำตาล โปรตีน หรือ กรดนิวคลีอิก ซึ่งรวมกันเป็นโครงสร้างที่ซับซ้อน หรือ อาจเป็นส่วนของเซลล์หรือเนื้อเยื่อที่มีชีวิต องค์การเพื่อการประเมินผลิตภัณฑ์จากยาแห่งสหภาพยุโรป (The European Agency for the Evaluation of Medicinal Products, EMEA) ให้คำจำกัดความของยาชีววัตถุว่า หมายถึง ผลิตภัณฑ์ใด ๆ ที่มีส่วนประกอบโปรตีนที่ได้จากเทคโนโลยีชีวภาพเป็นส่วนประกอบสำคัญ¹

Intraoperative Iris Prolapse

2023-08-21T16:30:58+07:00

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