TY - JOUR AU - Choomsri, Piyaporn AU - Bumpenboon, Wanichya AU - Wasuthit, Yodying AU - Euanorasetr, Chakkrapan AU - Sumritpradit, Preeda AU - Suwanthunma, Weerapat AU - Lertsithichai, Panuwat PY - 2010/03/31 Y2 - 2024/03/29 TI - Upper Gastrointestinal Endoscopy Findings in Patients Presenting with Dyspepsia JF - The Thai Journal of Surgery JA - Thai J Surg VL - 31 IS - 1 SE - Original Articles DO - UR - https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/227825 SP - AB - <div><strong>Objective:</strong> To determine the prevalence of important upper gastrointestinal (UGI) lesions in patients<br>with dyspepsia and to determine the associated risk factors.</div><div><br><strong>Methods:</strong> A prospective cohort study on dyspeptic patients undergoing UGI endoscopy during the<br>period between May 2006 and October 2008 was conducted. A questionnaire was administered to all patients<br>who consented to participate in the study. Endoscopic findings were defined as important if lesions seen were<br>gastric or duodenal ulcers, moderate to severe gastritis, severe esophagitis, adenomatous polyps or cancer.<br>Histological examination results were obtained for patients who also underwent endoscopic biopsy.</div><div><br><strong>Results:</strong> A total of 291 dyspeptic patients were enrolled. Only 19% (54/291) of patients had important<br>endoscopic lesions. No clinical findings including age and alarm symptoms were related to important<br>endoscopic lesions. In 132 patients, 23% (30/132) of the endoscopic biopsies showed evidence of H. pylori<br>infection. In patients with endoscope biopsy results, H. pylori infection was not associated with important<br>endoscopic findings.</div><div><br><strong>Conclusion:</strong> Dyspeptic patients had a low prevalence of important endoscopic lesions. The presence of<br>these lesions could not be reliably predicted using clinical data and H. pylori infection status. Empirical antiacid<br>therapy was recommended as the initial screening therapeutic test prior to endoscopic evaluation for most<br>patients.</div> ER -