@article{Songsaeng, MD_Jarunnarumol, MD_Thephamongkhol, MD_Setakornnukul, MD_Anusasnee, MD_2021, title={Usefulness of Arterial Spin Labeling-Tumor Blood Flow and Dynamic Contrast-Enhanced Perfusion Techniques in Predicting Treatment Response of Nasopharyngeal Carcinoma}, volume={17}, url={https://he02.tci-thaijo.org/index.php/bkkmedj/article/view/250507}, DOI={10.31524/bkkmedj.2021.21.007}, abstractNote={<p><strong>OBJECTIVES</strong>: To demonstrate the usefulness of arterial spin labeling (ASL)- tumor blood flow (TBF) and dynamic contrast enhancement (DCE) parameters in predicting the treatment response in patients with nasopharyngeal carcinoma (NPC) after 3-months of radiotherapy.</p> <p><strong>MATERIALS AND METHODS</strong>: Ten NPC patients who underwent magnetic resonance imaging (MRI) examinations with both ASL-TBF and DCE techniques before treatment and at the 3-month follow-up after radiotherapy were divided into complete-response (CR) and partial-response (PR) groups according to the Revised Response Evaluation Criteria in Solid Tumors (RECIST) guideline version 1.1. The ASL-TBF and DCE parameters of the nasopharynx comprised TBF, Ktrans, IAUGC, Kep, and Ve were analyzed and compared between the two groups.</p> <p><strong>RESULTS</strong>: The CR group had a significantly higher pre-treatment Ve ratio (p = 0.038), a higher post-treatment TBF value (p = 0.038), and a higher post-treatment K trans value (p = 0.067) than the PR group.</p> <p><strong>CONCLUSION</strong>: The ASL-TBF and DCE techniques might be useful tools for the prediction of the treatment responses 3-months after radiotherapy in patients with NPC.</p>}, number={2}, journal={The Bangkok Medical Journal}, author={Songsaeng, MD, Dittapong and Jarunnarumol, MD, Natthawut and Thephamongkhol, MD, Kullathorn and Setakornnukul, MD, Jiraporn and Anusasnee, MD, Niyada}, year={2021}, month={Sep.}, pages={132} }