Mahidol Dental Journal https://he02.tci-thaijo.org/index.php/mdentjournal <p><em><strong> Mahidol Dental Journal<br /> </strong></em>Academic journals are essential for serving as a forum for knowledge sharing, thought-provoking, and disseminating innovation. It is also a platform providing for researchers to have their work published and archived. The mission of the Faculty of Dentistry, Mahidol University, is to gather educational resources relating to dentistry and provide access to the scientific community and those who are interested. Accordingly, Mahidol Dental Journal was established in 1985 and has been published triannually since then.</p> <p><em><strong>Objectives<br /> </strong></em>1. To provide a reliable source of information in the field of Dentistry.<br /> 2. To advocate research and valuable studies devoted to academic advancement.<br /> 3. To be a center of in-depth and updated knowledge for lifelong learning among dentists and other interdisciplinary audiences.<br /> 4. To contribute to the community as an honor of the Faculty of Dentistry, Mahidol University.<br /><em><strong>Editorial policies</strong></em> - Articles submitted to the publication will go through the process listed below<br /> 1. Authors will be informed when the articles have been submitted properly.<br /> 2. Title and content of the article will be reviewed by the editorial team if it is valid, beneficial, and relevant to the scope of the journal.<br /> 3. The article will be evaluated by <strong>at least three experts</strong> in each field according to the Thai Journal Citation Index Center (TCI). <strong>The reviewing process is double-blinded.</strong><br /> 4. After the experts-review, the editorial team will inform the author if the article was declined, revision required, or accepted.<br /> 5. The approved article will proceed to publication in the Mahidol Dental Journal.</p> <p> 6. <strong>The authors will not have to pay any processing fee or article page charge (APC) during the submission, evaluation, and publication process.</strong></p> <p><strong>Journal abbreviation:</strong> M Dent J</p> <p>Mahidol Dental Journal publishes trianually as the following schedule,<br /> <strong>Issue 1 </strong>January- April<br /> <strong>Issue 2 </strong>May - August<br /> <strong>Issue 3</strong> September - December</p> <p><strong>Language:</strong> English</p> <p><strong>ISSN: 2773-8906 (Online)</strong><br /><strong>ISSN: 0125-5614 (Print)</strong></p> Faculty of Dentistry Mahidol University en-US Mahidol Dental Journal 0125-5614 An overview of sleep bruxism and management, a review https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/277635 <p>The concept of sleep bruxism (SB) has evolved over the past several decades. Many theories and hypotheses have been proposed as to the definition, pathophysiology, and management of SB. An international consensus was attained on the definition of SB as masticatory muscle activities that occur during sleep (characterized as rhythmic or non-rhythmic). The etiology of bruxism is not well known, but it is believed to be multifactorial. Assessment tools of bruxism may be made by patient report, clinical interview, clinical examination, and instrumental assessment, leading to diagnostic criteria that challenge to provision of scientifically proven information regarding SB management. Several investigations have been carried out to confirm the safety and efficacy of various kinds of treatment aimed at solving bruxism. In addition, the methodological quality, the different criteria of SB diagnosis, and the lack of homogeneity in terms of study design can result in poor meta-analysis data, mislead readers, and induce malpractice. These issues are also discussed. </p> Jarika Leeraphongnan Pirabhorn Wichienroj Copyright (c) 2025 Mahidol Dental Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2025-11-07 2025-11-07 45 3 214 228 Effect of accelerated aging on phase transformation and flexural strength of yttria-stabilized tetragonal zirconia dental ceramics https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/276203 <p><strong>Objectives: </strong>The objectives of this study were to investigate the effect of hydrothermal aging on the flexural strength and the transformation behavior of two translucent (Cercon xt ML and Ceramill Zolid FXML) and two conventional (Cercon ht and Ceramill ZI) dental zirconia (Y-TZP).</p> <p><strong>Materials and methods:</strong>Five bar-shaped specimens (1.5 x 4 x 22 mm) of zirconia in each group were subjected to hydrothermal aging process at 134°C under 0.2 MPa for 0, 10 and 50 hours. After aging, the monoclinic-to-tetragonal phase transformation was evaluated using an x-ray diffraction technique. The alteration in material microstructure was observed using a scanning electron microscope. The flexural strength of all specimens was determined using a four-point bending test. Two-way ANOVA was used to analyze the flexural strength values to find the significant differences among groups at α =.05.</p> <p><strong style="font-size: 0.875rem;">Results:</strong>The results showed that there was a significant increase in flexural strength of Ceramill ZI and Cercon ht after autoclaving for 10 hours and 50 hours. The flexural strengths of Ceramill Zolid FXML and Cercon xt ML were not significantly different at all autoclaving times. After 50 hours of autoclaving, the monoclinic phase increased from 0.2 to 69.40 wt% for Ceramill ZI, and from 0 to 70.03 wt% for Cercon ht. There was also no relevant effect of aging on grain size or topography at the surface of all Y-TZPs groups. </p> <p><strong style="font-size: 0.875rem;">Conclusions:</strong>Prolonged hydrothermal aging caused an increase in monoclinic phase content in conventional dental zirconia and a significant increase in flexural strength was also observed in this group. However, prolonged hydrothermal aging had limited effect on flexural strength and amount of monoclinic phase change observed in the translucent dental zirconia group. </p> Pichavipa Maluangnon Amornrat Wonglamsam Porntida Visuttiwattanakorn Kallaya Suputtamongkol Copyright (c) 2025 Mahidol Dental Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2025-11-04 2025-11-04 45 3 173 184 A multi-center retrospective analysis of oral and maxillofacial lesions in the southernmost region of Thailand https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/276134 <p><strong>Objectives:</strong> This multi-center retrospective study aimed to analyze the demographic distribution, lesion characteristics, and referral patterns of oral and maxillofacial lesions (OMFLs) in Thailand’s three southernmost provinces.</p> <p><strong>Materials and Methods: </strong>Histopathologically confirmed OMFLs diagnosed from 2018-2024 were reviewed using records of four public hospitals representing Thailand’s healthcare system tiers. Lesions were categorized as soft tissue lesions (STLs) or odontogenic and maxillofacial bone tumors (OMBTs), and analyzed by age, sex, anatomical site, and referral level. Statistical analyses included the Mann– Whitney U test and Pearson’s Chi-Square test (<em>p</em> &lt; 0.05).</p> <p><strong>Results: </strong>A total of 512 OMFLs were identified. STLs (53.7%) slightly outnumbered OMBTs (46.3%). Patients with STLs were significantly older than those with OMBTs (median age: 46 [IQR 23-60] vs. 28 [IQR 19-44] years;<em> p</em> &lt; 0.001). The most common STLs were mucosal and soft tissue tumors, particularly irritation fibroma (IF) in the buccal mucosa and pyogenic granuloma (PG) in the gingiva. IF was predominant in patients over 40, while PG mainly affected those under 40. Mucoceles were the most frequent salivary gland lesions in younger patients. Jaw cysts were the most common OMBTs, with radicular cysts more prevalent in the maxilla and dentigerous cysts in the mandible. Ameloblastoma, primarily found in the mandible, was the most frequent odontogenic tumor. Within the four-tier healthcare system of the study area, complex cases tended to escalate to higher tiers. All oral cancer (OC) cases appeared at provincial hospitals (third-tier), as at the regional (highest) level they were diverted to ENT, reflecting interdepartmental separation of case management.</p> <p><strong>Conclusion: </strong>OMFLs in this region show distribution patterns consistent with previous reports. Progressive management trends reflect Thailand’s structured referral system. Lower-tier hospitals can aid OC control through early detection and gatekeeping referral, while bridging interdepartmental gaps may strengthen OC case coordination at the regional level.</p> Srisuk Khwankong Pheera Charoensuk Piyanat Boontarig Chutiporn Kerdtip Copyright (c) 2025 Mahidol Dental Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2025-11-04 2025-11-04 45 3 185 200 Effects of 40% hydrogen peroxide on the surface roughness and biofilm formation of three different types of resin composites https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/277141 <p style="font-weight: 400;"><strong>Objective: </strong>This study aimed to examine the effects of hydrogen peroxide on three different resin composites (Z250: microhybrid, Z250XT: nanohybrid, and Z350XT: nanocomposite) in terms of surface roughness alteration and biofilm formation.</p> <p style="font-weight: 400;"><strong>Materials and Methods: </strong>Forty-two samples were prepared from each material and then randomly divided into two groups for investigation. In total, 20 samples were used to determine the surface roughness, and the remaining 22 samples were used to determine biofilm formation. Finally, the samples were divided into two subgroups: the bleached group and the nonbleached group. In the bleached group, the samples were bleached with 40% hydrogen peroxide (opalescence boost). The bleaching procedures were conducted following the manufacturer’s instructions. The surface roughness was assessed using an arithmetical mean height of an area (Sa) by a laser scanning microscope. For biofilm measurement, S. mutans was cultured on each sample coated with the acquired pellicle and stained with a Live/Dead Bac LightTM Bacterial Viability Kit. Biofilm formation was measured under a confocal laser scanning microscope.</p> <p style="font-weight: 400;"><strong>Results: </strong>The surface roughness significantly differed among the three groups of materials without bleaching (<em>p</em>=0.000) and with bleaching (<em>p</em>=0.000). The roughness of Z250 was significantly greater than that of the other two samples, while no significant difference between Z350XT and Z250XT was observed. Compared with that of the samples without bleaching, the surface roughness of the three types of resin composites was significantly different (<em>p</em>&lt;0.05). For biofilm formation, no significant differences among the groups were observed.</p> <p style="font-weight: 400;"><strong>Conclusions: </strong>Bleaching affected the Sa of three different types of resin composites, but the change in Sa had no effect on the average volume of colonies at the substratum of S. mutans biofilms. The resin-based materials Z250, Z350XT and Z250XT represent potentially suitable materials for aesthetic restoration, and the 40% hydrogen peroxide bleaching agent had no adverse effects. </p> Jantanee Leelanarathiwat Pisol Senawongse Ratchapin Srisatjaluk Copyright (c) 2025 Mahidol Dental Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2025-11-04 2025-11-04 45 3 201 213