Ramathibodi Medical Journal https://he02.tci-thaijo.org/index.php/ramajournal <p>Ramathibodi Medical Journal (RMJ) publishes article on clinical and laboratory medicine, health care policy and economics, medical education and ethics, and related topics. We welcome submissions from authors worldwide.</p> <p>ISSN 0125-3611 (Print)&nbsp;</p> <p>ISSN 2651-0561 (Online)</p> <p>Indexed in:&nbsp;&nbsp;<strong>&nbsp;&nbsp;<a title="ASEAN CITATION INDEX" href="https://www.asean-cites.org/" target="_blank" rel="noopener"><img src="/public/site/images/nuanphan_cha2/aci-logo-v41.png" width="100" height="40"></a>&nbsp; &nbsp;&nbsp;</strong><a title="ศูนย์ดัชนีการอ้างอิงวารสารไทย:Thai Citation Index (TCI) centre" href="https://tci-thailand.org/" target="_blank" rel="noopener"><img title="tci" src="/public/site/images/tci_admin/tci.png" width="86" height="38" border="0"></a>&nbsp;&nbsp; &nbsp;<a title="Crossref" href="https://search.crossref.org/?q=ramathibodi&amp;container-title=Ramathibodi+Medical+Journal" target="_blank" rel="noopener"><img src="/public/site/images/nuanphan_cha2/images.png" width="77" height="50">&nbsp;</a>&nbsp; &nbsp;&nbsp;<a title="Google Scholar" href="https://scholar.google.co.th/citations?user=N7b2p9MAAAAJ&amp;hl=th&amp;authuser=1" target="_blank" rel="noopener"><img src="/public/site/images/nuanphan_cha2/scholar_logo_64dp_(1).png" width="155" height="26"></a></p> Faculty of Medicine Ramathibodi Hospital, Mahidol University, THAILAND en-US Ramathibodi Medical Journal 0125-3611 Osteoporosis Preventive Behavior Among Female Healthcare Students in Da Nang, Vietnam https://he02.tci-thaijo.org/index.php/ramajournal/article/view/249920 <p style="text-align: justify;"><strong>Background:</strong> Osteoporosis prevention at young ages is crucial to diminish the risk of the disease and its complication in later years of life. Having good osteoporosis knowledge and positive health belief may lead to better preventive behavior which then contributes to build and maintain bone health throughout life.</p> <p style="text-align: justify;"><strong>Objective:</strong> To investigate knowledge, health belief, and behavior of osteoporosis prevention among female healthcare students.</p> <p style="text-align: justify;"><strong>Methods:</strong> The descriptive cross-sectional study was conducted in a public medical university in Da Nang of Vietnam. Four hundred participants were selected by applying the multistage sampling technique. Data were collected from May 2020 to June 2020 through the questionnaire that consists of 4 parts including the demographic data form, the osteoporosis knowledge assessment tool, the osteoporosis health belief scale, and the exercise and calcium behaviors scale. Data were analyzed using descriptive statistics and Pearson correlation test.</p> <p style="text-align: justify;"><strong>Results:</strong> Participants had poor osteoporosis knowledge (mean [SD], 37.8 [16.0]; range, 0 - 75) and low preventive behavior (mean [SD], 5.7 [3.5]; range, 0 - 25). Osteoporosis health belief was found at a moderate level with a mean (SD) of 126.7 (12.9) (range, 84 - 187). There were positive significant correlations between knowledge and health belief, knowledge and behavior of osteoporosis prevention (<em>P</em> &lt; .05).</p> <p style="text-align: justify;"><strong>Conclusions:</strong> Osteoporosis preventive behavior of female healthcare students was low. Osteoporosis education programs should be developed for female healthcare students to improve their knowledge and health belief that would then lead to their better preventive behavior.</p> <p style="text-align: justify;">&nbsp;</p> Dang Thi Nhien Luu Thi Thuy Hoang Thi Ngoc Sen Huynh Thi Ly Pham Thi Thuy Copyright (c) 2021 Ramathibodi Medical Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2021-09-24 2021-09-24 44 3 1 11 10.33165/rmj.2021.44.3.249920 Prevalence, Types, and Factors of HPV Infection Among Women With Abnormal Cervical Cytology Screening at Ramathibodi Hospital https://he02.tci-thaijo.org/index.php/ramajournal/article/view/249847 <p style="text-align: justify;"><strong>Background:</strong> Cervical cancer is the second leading cancer among Thai women. Human papillomavirus (HPV) is the most common cause of cervical cancer. HPV16 and HPV18 are the most prevalence types in women with cervical cancer.</p> <p style="text-align: justify;"><strong>Objectives:</strong> To study the prevalence and types of HPV infection and its associated risk factors among women with abnormal cervical cytology screening.</p> <p style="text-align: justify;"><strong>Methods:</strong> This cross-sectional study purposively recruited 376 women who had abnormal cervical cytology screening by liquid-based cytology at the outpatient clinic, Ramathibodi Hospital from August 2015 until March 2016. HPV genotyping was done by the polymerase chain reaction (PCR). Analysis of the personal characteristics was done using descriptive statistics.</p> <p style="text-align: justify;"><strong>Results:</strong> The prevalence of HPV infection was 41.5%. Among them, a single infection was found in 78.8% of women. The most common genotypes were HPV16 (8.5%) and HPV52 (7.7%). But HPV18 was found in only 1.9%. The characteristic which was significantly associated with HPV infection was age, nulliparity, and high-graded dysplasia (<em>P </em>&lt; .05).</p> <p style="text-align: justify;"><strong>Conclusions:</strong> High prevalence rate of HPV infection was found among women with abnormal cytology. High-risk HPV prevalence and type distribution may be useful for public health authorities in assessing the cervical screening program.</p> <p>&nbsp;</p> Nithitda Boonthum Somsak Suthutvoravut Copyright (c) 2021 Ramathibodi Medical Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2021-09-24 2021-09-24 44 3 12 19 10.33165/rmj.2021.44.3.249847 Development of Antenatal Care Pamphlet in Burmese https://he02.tci-thaijo.org/index.php/ramajournal/article/view/246881 <p style="text-align: justify;"><strong>Background: </strong>Currently, there are many foreign workers working in Thailand. Majority of them are Myanmar. Providing information on antenatal care to Burmese women is one of the guidelines in providing knowledge for antenatal care.</p> <p style="text-align: justify;"><strong>Objective: </strong>To develop a pamphlet on antenatal care in Burmese language.</p> <p style="text-align: justify;"><strong>Methods: </strong>This study was on research and development. The tools used in the research were the pamphlet development and pamphlet evaluation forms. The back translation method was used for translation by using Thai language pamphlet that modifies for the optimal features and information appropriate for the clients.</p> <p style="text-align: justify;"><strong>Results: </strong>The process of translating and developing research tools was started from Step 1: translating the contents of pamphlet from Thai to Burmese, obtaining the pamphlets B1 and B2. Step 2: conducting a preliminary test by bringing the two Burmese language pamphlets to test with the participants that can communicate in Burmese language and evaluate the pamphlet features. It was found that the majority of 3 in 5 people were satisfied with the B2 pamphlet at an excellent level. This step aimed to consider the clarity of the language idioms used. Step 3: reviewing the suitability of the culture by introducing the Burmese pamphlet and preliminary tests checked by experts who understand the context and culture of Myanmar. Step 4: synthesizing the translated version of the tool by collecting information that is appropriate for the context and culture of the Burmese people to synthesize as a new Burmese pamphlet. Step 5: translating the contents of the pamphlet back from Burmese to Thai language. And Step 6: checking the equality of translation and draw conclusions.</p> <p style="text-align: justify;"><strong>Conclusions: </strong>From all processes mentioned above, we got the Burmese antenatal care pamphlet that is appropriate in terms of content and culture.</p> <p>&nbsp;</p> Piamboon Tanabatchai Nilawan Upakdee Kultida Chaijinda Copyright (c) 2021 Ramathibodi Medical Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2021-09-24 2021-09-24 44 3 20 28 10.33165/rmj.2021.44.3.246881 Correlation of Composite Indices and COPD Assessment Test in Thai COPD Patients https://he02.tci-thaijo.org/index.php/ramajournal/article/view/242498 <p style="text-align: justify;"><strong>Background:</strong> Chronic obstructive pulmonary disease (COPD) is a common preventable and treatable chronic respiratory diseases. The BODE, ADO, DOSE are the composite indices taking into consideration for prognostication. In addition, COPD assessment test (CAT) score is associated with quality of life, taken for assessing symptoms severity and for personalizing treatments.</p> <p style="text-align: justify;"><strong>Objective: </strong>To investigate the CAT score in Thai COPD patients according to their BODE, ADO, and DOSE in the influence of clinical parameters and outcomes.</p> <p style="text-align: justify;"><strong>Methods:</strong> Medical records were reviewed between January 2016 and December 2016. BODE, ADO and DOSE was calculated based on their individual components.</p> <p style="text-align: justify;"><strong>Results:</strong> Total 125 consecutive COPD patients were recruited. There was difference between CAT score among the GOLD stages classified (<em>P</em> = .02). There was significant difference of CAT between 4 BODE quartiles in cohort (<em>P</em> = .001).Thai COPD patients had the higher ADO index exhibit the higher CAT score than those with the lower ADO index (<em>P</em> = .001). There was no difference in CAT score between COPD with the higher and the lower DOSE index (<em>P</em> = .05).</p> <p style="text-align: justify;"><strong>Conclusions: </strong>The higher CAT score found in Thai COPD patients with the higher composite indices of BODE and ADO. However, there was no difference in the DOSE index.</p> <p style="text-align: justify;">&nbsp;</p> Supattra Khiawwan Theerasuk Kawamatawong Copyright (c) 2021 Ramathibodi Medical Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2021-09-24 2021-09-24 44 3 29 40 10.33165/rmj.2021.44.3.242498 Quality of Life in Patients With Systemic Lupus Erythematosus Ramathibodi Hospital https://he02.tci-thaijo.org/index.php/ramajournal/article/view/245850 <p style="text-align: justify;"><strong>Background: </strong>Systemic Lupus Erythematosus (SLE) is an autoimmune disease. It is a chronic disease and exhibits symptoms in many organs and patients will be offered a variety of immunosuppressants, which may cause many side effects and worsen the quality of life.</p> <p style="text-align: justify;"><strong>Objective:</strong> To study the quality of life in SLE patients receiving treatment in Ramathibodi Hospital.</p> <p style="text-align: justify;"><strong>Methods:</strong> A cross-sectional study of all SLE patients were collected during February 2017 to February 2018, by using questionnaires to measure the quality of life.</p> <p style="text-align: justify;"><strong>Results:</strong> Total of 510 SLE patients, 96.7% were female. The mean (SD) age was 40.9 (13.0) years, and the disease duration was 10.5 (8.2) years. Most of them got a bachelor’s degree or higher (54.1%). Universal coverage scheme was the most treatment welfare of the patients. Despite the disease limitation for pregnancy, 7.2% of the SLE patients had 3 children while only 17.0% had miscarriages while pregnant. The general quality of life (SF-36) was in a good level, and disease-specific quality of life (SLEQoL) was at a moderate level. The older patients and a longer disease duration were inversely related to quality of life including physical health, overall health.</p> <p style="text-align: justify;"><strong>Conclusions:</strong> SLE patients who received the treatment at Ramathibodi Hospital had a relatively good quality of life. Factors related to quality of life were age and duration of the disease.</p> <p>&nbsp;</p> Thanuchporn Kafaksom Nichapha Dechapaphapitak Thanitta Suangtamai Pintip Ngamjanyaporn Dhanesh Pitidhammabhorn Nopparat Ruchakorn Copyright (c) 2021 Ramathibodi Medical Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2021-09-24 2021-09-24 44 3 41 50 10.33165/rmj.2021.44.3.245850 Leukemoid Reaction in a Case of Chronic Cholecystitis With Focal Mild Acute Inflammation https://he02.tci-thaijo.org/index.php/ramajournal/article/view/250706 <p style="text-align: justify;">Leukemoid reaction is a rare condition of marked increase of the white blood cells (WBC) in the peripheral blood, mostly more than 50 × 10<sup>9</sup>/L. Although its most common cause is infection, acute or chronic cholecystitis has been hardly mentioned. This report aimed to present the leukemoid reaction found in a Thai who had chronic cholecystitis with focal acute inflammation. A 74-year-old woman had low-graded fever and generalized vague abdominal discomfort for 2 days. The physical examination showed the body temperature 37.7 °C and unremarkable abdominal signs. Her blood tests showed: hemoglobin 9.0 g/L, WBC 52.48 × 10<sup>9</sup>/L, neutrophil 91%, band form 1%, platelet 434 × 10<sup>9</sup>/L, and alkaline phosphatase (ALP) 290 U/L. The blood cultures yielded no growth. The computed tomography of the abdomen revealed 2 stones in the common bile duct (CBD) causing obstruction; the gall bladder (GB) showed mild dilatation with thin wall containing multiple small gall stones; no pericholecystic fluid and normal size of spleen. She promptly underwent operative cholecystectomy, CBD choledochoscopy, stones removal and T-tube choledochostomy. Along with the surgery, intravenous ertapenem was also administered. The pathology of the gall bladder was chronic cholecystitis with focal mild acute inflammation. With these therapies, fever daily decreased and finally disappeared within 5 days meanwhile the WBC count also gradually diminished every day till 8.04 × 10<sup>9</sup>/L within 7 days. The WBC count was still normal one month later. The diagnosis of leukemoid reaction was concluded and it was presumably be associated with chronic calculous cholecystitis with focal acute inflammation although the BCR-ABL translocation had never been explored.</p> <p style="text-align: justify;">&nbsp;</p> Likhasit Sanglutong Somchai Insiripong Taweechai Wisanuyothin Copyright (c) 2021 Ramathibodi Medical Journal https://creativecommons.org/licenses/by-nc-nd/4.0 2021-09-24 2021-09-24 44 3 51 56 10.33165/rmj.2021.44.3.250706