@article{Wongphan_Bundhamcharoen_2018, title={Health-Related Quality of Life as Measured by EQ-5D and TFLIC-2 in Liver Cancer Patients}, volume={70}, url={https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/152645}, abstractNote={<p><strong>Objective</strong>: To assess the relation and estimation function between utility weight (UW) from EQ-5D and T-FLIC<br>2 score (TFS). To compare quality of life (QOL) between global burden of disease (GBD) and TNM staging.<br><strong>Methods</strong>: All liver cancer patients which presented in selected hospitals in 2009, were asked their QOL by EQ-5D<br>and T-FLIC 2 questionnaires. The relation between UW and TFS was analyzed by using Pearson’s correlation and<br>the linear regression. The means of UW and TFS in specific conditions were compared with independent t-test<br>and ANOVA.<br><strong>Results</strong>: There were 53 cases. The majority (73.6 %) were men, mean age was 57.2 years, lived in suburban area<br>(67.9%), worked in agriculture (47.2%) and graduated secondary level or lower (83.0%). These 73.6% of all samples<br>had household monthly income not greater than 5,000 THB and used universal coverage scheme (64.2%). Seventeen<br>cases had not been identified TNM staging because of the condition of patients. However, those cases fulfilled to be<br>diagnosed terminal stage. The multiple comparisons between means of UW and TFS showed no statistical significance<br>e.g. pre-terminal and terminal (0.5 vs 0.4, p=0.3 and 38.8 vs 34.0, p=0.2 respectively), TNM-stage 4 vs TNM-stage<br>1-3 (0.3 vs 0.5, p=0.3 and 38.9, 30.5, p=0.1), and supportive only vs. other treatment (0.5 vs 0.5, p=0.9, and 32.8 vs<br>36.2, p=0.5). The correlation between UW and TFS was significantly related (p<0.001) with linear pattern (p<0.001).<br>The equation for estimating UW from TFS and specific Q1-Q22 questions was formulated.<br><strong>Conclusion</strong>: This study revealed the significant correlation between UW and TFS with linear pattern. A major<br>advantage of using regression analysis was predicting UW from TFS for economic evaluation in Thai liver cancer<br>patients. The treatment might not alter QOL significantly. Given cancer stage and treatment choice and their QOL<br>in this study, our findings should not be over-interpreted.</p>}, number={5}, journal={Siriraj Medical Journal}, author={Wongphan, Thanawat and Bundhamcharoen, Kanitta}, year={2018}, month={Oct.}, pages={406–412} }