TY - JOUR AU - Kolladaruengkri, Teera AU - Udol, Kamol AU - Sangsiriwut, Kantima AU - Pisalsarakij, Dujpratana AU - Suwanagool, Surapol PY - 2003/03/01 Y2 - 2024/03/28 TI - Amikacin: Area Under Curve for Once Daily Dose and Its Correlation with Plasma Concentration at Six Hours Post Infusion JF - Siriraj Medical Journal JA - Siriraj Med J VL - 55 IS - 3 SE - Original Article DO - UR - https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/245387 SP - 133-138 AB - <p>Aminoglycosides are commonly used for gram-negative septicemia. Formerly, peak and trough plasma levels were the monitoring parameters for conventional dose which was every eight hours. At present the recommended dose is once daily and the recommended monitoring parameters are the area under concentration time curve and the six-hour (range 146-180) for the area under curve and 6.79 milligrams per liter (range 5.6-7.9) for the six-hour plasma concentration post-infusion. The correlation of the area under curve and the six-hour plasma concentration post-infusion was reported in a linear equation with significance.</p> ER -