Exercise as an Anti-Hypertensive Tool: Scientific Mechanisms
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Abstract
บทคัดย่อ โรคความดันโลหิตสูง )hypertension (เ ป็น โ ร ค ท า ง ร ะ บ บ หัว ใ จ แ ล ะ ห ล อ ด เ ลือ ด) cardiovascular diseases; CVD) ที่มีความบกพร่องของทั้งโครงสร้างและการทางานของ หัวใจและหลอดเลือด การออกกาลังกายถือเป็นวิธีหนึ่งของการรักษาโรคความดันโลหิตสูงแบบไม่ใช้ยา ) non-pharmacologic intervention( ที่ได้รับการยอมรับอย่างแพร่หลาย โดยแบ่งเป็นสองชนิดหลักๆ คือ การออกกาลังกายแบบแอโรบิก(aerobic exercise) แ ล ะ แ บ บ ใ ช้แ ร ง ต้า น(resistance exercise) แต่อย่างไรก็ตาม กลไก(mechanism) ที่อธิบายผลของการออกกาลังกายต่อการลดความดันโลหิตนี้ ยังไม่มีความชัดเจนและยังมีข้อขัดแย้งในบางประเด็น บทความนี้จึงมุ่งเน้นทบทวนงานวิจัยที่ศึกษากลไกที่อธิบายผลของการออกกาลังกายทั้งเฉียบพลันและการฝึกต่อร่างกายทั้งระดับระบบต่าง ๆ จนถึงระดับโมเลกุล
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