Applications of concentrated growth factor (CGF) to enhance osteogenesis in dentistry: report of 4 cases
Article Sidebar
Main Article Content
Abstract
Preparing various types of platelet concentrates using blood centrifugation have been introduced for acceleration of tissue regeneration. Concentrated growth factor (CGF), the second generation of platelet concentrates, contains many kinds of growth factors as well as fibrin. CGF has higher adhesive strength and tensile strength, and higher viscosity than other platelet preparations. It promotes wound healing and accelerates osteogenesis. This article focused on the preparation and clinical application of CGF, and 4 cases were reported.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The opinions and content expressed in the articles are solely those of the individual authors and do not necessarily reflect the views of the journal or the authors’ affiliated institutions. Authors are fully responsible for the accuracy and correctness of their work.
Any reuse, reproduction, or redistribution of the articles, content, data, or images in other forms requires prior written permission from the Thai Journal of Oral and Maxillofacial Surgery
References
Qiao J, An N, Ouyang X. Quantification of growth factors in different platelet concentrates. Platelets 2017;28:714-8.
Masuki H, Okudera T, Watanebe T, et al. Growth factor and proinflammatory cytokine contents in platelet-rich plasma (PRP), plasma rich in growth factor (PRGF), advanced platelet-rich fibrin (A-PRF) and concentrated growth factor (CGF). Int J Implant Dent 2016;2:19.
Sacco L. Lecture. In: International Academy of Implant Prosthesis and Osteoconnection, April 12th 2006. Cited in Bernardi S, Mummolo S, Tecco S, Continenza MA, Marzo G. Histological characterization of Sacco's. concentrated growth factors membrane. Int J Morphol 2017;35:114-9.
Sohn DS, Huang B, Kim J, Park WE, Park CC. Utilization of autologous concentrated growth factors (CGF) enriched bone graft matrix (sticky bone) and CGF-enriched fibrin membrane in implant dentistry. J Implant Advanced Clin Dent 2015;7:11-29.
Borsani E, Bonazza V, Buffoli B. Biological characterization and in vitro effects of human concentrated growth factor preparation: an innovative approach to tissue regeneration. Biol Med 2015;7:726.
Park HC, Kim SG, Oh JS, et al. Early bone formation at a femur defects using CGF and PRF grafts in adult dogs: a comparative study. Implant Dent 2016;25:387-93.
Qiao J, Duan J, Zhang Y, Chu Y, Sun C. The effect of concentrated growth factors in the treatment of periodontal intrabony defects. Future Sci OA 2016;2:FS136.
Park IS, Sohn DS. Maxillary sinus elevation using concentrated growth factor (CGF). Int J Oral Maxillofac Surg 2011;40:1133.
Bozkurt DS, Ongoz DF, Balli U, et al. Concentrated growth factor in the treatment of adjacent multiple gingival recession: a split-mouth randomize clinical trial. J Clin Periodontol 2015;42:868-75.
Runza J, Guangtai S, Jihua C, et al. Effects of concentrated growth factor on proliferation, migration, and differentiation of human dental pulp stem cells in vitro. J Tissue Eng 2018;9:1-10.
Nityasri, Aromal S, Pradeep KY, et al. Role of CGF (concentrated growth factor) in periodontal regeneration. J Dent Health Oral Disord Ther 2018;9:350-2.
Gökmenoğlu C, Yavuz MC, Sadik E, Çanakçi V, Kara C. Treatment of different types of bone defects with concentrated growth factor: four cases report. Int J Oral Dent Health 2016;2:029.
Rodella LF, Bonazza V. platelet preparation in dentistry: How? Why? Where? When? J Stomatol 2015;4:39-55.
Forabosco A, Gheno E, Spinato S, Garuti G, Forabosco E, Consolo U. Concentrated growth factors in maxillary sinus floor augmentation: a preliminary clinical comparative evaluation. Int J Growth Factors Stem Cells Dent 2018;1:2-7.
Bhattacharya P, Bhattacharya H, Anjum A, et al. Assessment of corticotomy facilitated tooth movement and changes in alveolar bone thickness – a CT scan study. J Clin Diagn Res 2014;8:ZC26-30.
Wang B, Shen G, Guo Q, Fang B, Yu H. Long-term effects of augmented corticotomy-assisted orthodontics in patients with mandibular anterior alveolar defect. J Craniofac Surg 2019;30:e737-40.
