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The World Health Assembly 74th in 2021 has adopted the WHO Global Strategic Directions for Nursing and Midwifery (SDNM) 2021-2025. Nurses and frontline health workers were praised for their dedication during COVID-19 pandemic. To resolve chronic issues of nursing workforce agenda, the SDNM focuses on the investment to enhance the capacity of nurses in responding effectively to current health challenges. The SDNM encompasses the four areas of education, jobs, leadership, and service delivery by optimizing practice that are safety for both personnel and patients. The strategic direction of nursing in Thailand will align with global strategic direction but will be tailored to fit Thai context and national health priority. The visions of the nurse leaders focus primarily on new care design, health development in community care, primary care, innovation, health, and information technology that is feasible to provide safety remote care. The roles of advanced practice nurses in care delivery are highlighted to promote better health accessibility and equity to ensure the achievement of sustainable development goals. The visions of the nurse leaders are, therefore, crucial to accelerate the achievement of these goals through the collective power of nurses as the theme of International Nurses Day 2021 proposed by the International Council of Nurses (ICN) as “ Nurses: A Voice to Lead - A vision for future healthcare ” proposed by the International Council of Nurses (ICN) as “ Nurses: A Voice to Lead -A vision for future healthcare. ”
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