Tools predicting severity of physiological deterioration in patients with sepsis in emergency room

Main Article Content

Phoomin Doungsuriya
Kulisara Khunpinit

Abstract

Septicemia is classified as an emergency because the body cannot respond to the infectious process, which causes changes in the entire circulatory system and increases anaerobic metabolism, leading to multiple organ failures and, eventually, death. Proper diagnosis can timely be admitted for treatment. Furthermore, the first necessary process is to look for threats from the assessment of signs and symptoms, including selecting appropriate tools to predict the severity and physiological changes of patients with sepsis. With this intention, it is imperative to assess symptom capture tools, including Systemic Inflammatory Response Syndrome (SIRS), Quick Sequential Organ Failure Assessment score (qSOFA score), Sequential Organ Failure Assessment score (SOFA score), Modified Early Warning Signs (MEWs), Search Out Severity score (SOS score) and National Early Warning Score (NEWS2). This paper presents the tools to predict the severity of physiological changes in patients with sepsis treated in the emergency room to find threats that arise in advance, aiming to reduce the rate of illness and death.

Article Details

How to Cite
Doungsuriya , P. ., & Khunpinit, K. (2023). Tools predicting severity of physiological deterioration in patients with sepsis in emergency room. Thai Journal of Nursing, 72(2), 60–70. Retrieved from https://he02.tci-thaijo.org/index.php/TJN/article/view/259629
Section
Academic Article

References

กระทรวงสาธารณสุข กองตรวจราชการ. (2562). แผนการตรวจราชการ กระทรวงสาธารณสุข ประจําปี งบประมาณ พ.ศ. 2562. กระทรวงสาธารณสุข.

นนทรัตน์ จำเริญวงศ์, สุพรรณิการ์ ปิยะรักษ์, และ ชยธิดา ไชยวงษ์. (2563). การประเมินและการพยาบาลผู้ป่วยที่มีภาวะช็อกจากการติดเชื้อในกระแสเลือด. วารสารเครือข่ายวิทยาลัยพยาบาลและการสาธารณสุขภาคใต้, 7(1), 319-330.

ภานุวงส์ แสนสำราญใจ, และ พารณ ขันติโชติ. (2565). ความถูกต้องของ SOS score สำหรับการทำ นายการเสียชีวิตในโรงพยาบาลของผู้ป่วยฉุกเฉิน. วารสาร มฉก.วิชาการ, 26(1), 57-65.

Armstrong, B. A., Betzold, R. D., & May, A. K. (2017). Sepsis and septic shock strategies. Surgical Clinics of North America, 97(6), 1339 -1379.

Askim, Å., Moser, F., Gustad, L. T., Stene, H., Gundersen, M., Åsvold, B. O., Dale, J., Bjørnsen, L. P., Damås, J. K., & Solligård, E. (2017). Poor performance of quick-SOFA (qSOFA) score in predicting severe sepsis and mortality - a prospective study of patients admitted with infection to the emergency department. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 25(1), 56. doi:10.1186/s13049-017-0399-4

Cecconi, M., Evans, L., Levy, M., & Rhodes, A. (2018). Sepsis and septic shock. Lancet, 392(10141), 75–87.

Dellinger, R. P., Levy, M. M., Rhodes, A., Annane, D., Gerlach, H., Opal, S. M., Sevransky, J. E., Sprung, C. L., Douglas, I. S., Jaeschke, R., Osborn, T. M., Nunnally, M. E., Townsend, S. R., Reinhart, K., Kleinpell, R. M., Angus, D. C., Deutschman, C. S., Machado, F. R., Rubenfeld, G. D., . . . Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup. (2013). Surviving sepsis campaign: International guidelines for management of severe sepsis and septic shock, 2012. Intensive Care Medicine, 39(2), 165–228. doi: 10.1007/s00134-012-2769-8

Fujishima, S. (2016). Organ dysfunction as a new standard for defining sepsis. Inflammation and Regeneration, 36, 24.

Goulden, R., Hoyle, M. C., Monis, J., Railton, D., Riley, V., Martin, P., Martina, R., & Nsutebu, E. (2018). qSOFA, SIRS and NEWS for predicting inhospital mortality and ICU admission in emergency admissions treated as sepsis. Emergency Medicine Journal, 35(6), 345–349.

Gyawali, B., Ramakrishna, K., & Dhamoon, A. S. (2019). Sepsis: The evolution in definition, pathophysiology, and management. SAGE Open Medicine, 7, 1-13.

Heffernan, A. J., Judge, S., Petrie, S. M., Godahewa, R., Bergmeir, C., Pilcher, D., & Nanayakkara, S. (2022). Association between urine output and mortality in critically ill patients: A machine learning approach. Critical Care Medicine, 50(3), Article e263-e271. doi:10.1097/ccm.0000000000005310

Inada-Kim, M. (2022). NEWS2 and improving outcomes from sepsis. Clinical Medicine (London, England), 22(6), 514-517. doi:10.7861/clinmed.2022-0450

László, I., Trásy, D., Molnár, Z., & Fazakas, J. (2015). Sepsis: From pathophysiology to individualized patient care. Journal of Immunology Research, 2015, 510436. doi: 10.1155/2015/510436

Morgan, R. W., Fitzgerald, J. C., Weiss, S. L., Nadkarni, V. M., Sutton, R. M., & Berg, R. A. (2017). Sepsis-associated in-hospital cardiac arrest: Epidemiology, pathophysiology, and potential therapies. Journal of Critical Care, 40, 128-135.

Paoli, C. J., Reynolds, M. A., Sinha, M., Gitlin, M., & Crouser, E. (2018). Epidemiology and costs of sepsis in the United States - an analysis based on timing of diagnosis and severity level. Critical Care Medicine, 46(12), 1889-1897.

doi: 10.1097/CCM.0000000000003342

Pereira, F. H., Batalhao, M. E., & Carnio, E. C. (2014). Correlation between body temperature, blood pressure and plasmatic nitric oxide in septic patients. Revista Latino-Americana de Enfermagem, 22(1), 123-128.

Quinten, V. M., van Meurs, M., Renes, M. H., Ligtenberg, J. M., & Ter Maaten, J. C. (2017). Protocol of the sepsivit study: A prospective observational study to determine whether continuous heart rate variability measurement during the first 48 hours of hospitalisation provides an early warning for deterioration in patients presenting with infection or sepsis to the emergency department of a Dutch academic teaching hospital. BMJ Open, 7(11), Article e018259. doi:10.1136/bmjopen-2017-018259

Quinten, V. M., van Meurs, M., Olgers, T. J., Vonk, J. M., Ligtenberg, J., & Ter Maaten, J. C. (2018). Repeated vital sign measurements in the emergency department predict patient deterioration within 72 hours: A prospective observational study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 26(1), 57.

Royal College of Physicians (2017). National early warning score (NEWS) 2: Standardizing the assessment of acute-illness severity in the NHS. Updated report of a working party. Royal College of Physicians. https://www.rcplondon.ac.uk/projects/outputs/national-early-warning-score-news-2

Seymour, C. W., Liu, V. X., Iwashyna, T. J., Brunkhorst, F. M., Rea, T. D., Scherag, A., Rubenfeld, G., Kahn, J. M., Shankar-Hari, M., Singer, M., Deutschman, C. S., Escobar, G. J., & Angus, D. C. (2016). Assessment of clinical criteria for sepsis: For the third international consensus definitions for sepsis and septic shock (Sepsis-3). The Journal of the American Medical Association, 315(8), 762-774.

Singer, M., Deutschman, C. S., Seymour, C. W., Shankar-Hari, M., Annane, D., Bauer, M., Bellomo, R., Bernard, G. R., Chiche, J. D., Coopersmith, C. M., Hotchkiss, R. S., Levy, M. M., Marshall, J. C., Martin, G. S., Opal, S. M., Rubenfeld, G. D., van der Poll, T., Vincent, J. L., & Angus, D. C. (2016). The third international consensus definitions for sepsis and septic shock (Sepsis-3). The Journal of the American Medical Association, 315(8), 801-810. doi: 10.1001/jama.2016.0287

Valencia, A. M., Vallejo, C. E., Alvarez, A. L. L., & Jaimes, F. A. (2017). Attenuation of the physiological response to infection on adults over 65 years old admitted to the emergency room (ER). Aging Clinical and Experimental Research, 29(5), 847-856.

van der Woude, S. W., van Doormaal, F. F., Hutten, B. A., Nellen, F. J., & Holleman, F. (2018). Classifying sepsis patients in the emergency department using SIRS, qSOFA or MEWS. The Netherlands Journal of Medicine, 76(4), 158-166.

Wallgren, U. M., Sjölin, J., Järnbert-Pettersson, H., & Kurland, L. (2021). Performance of NEWS2, RETTS, clinical judgment and the predict sepsis screening tools with respect to identification of sepsis among ambulance patients with suspected infection: A prospective cohort study. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 29(1), 144. doi:10.1186/s13049-021-00958-3

Wang, H. E., Jones, A. R., & Donnelly, J. P. (2017). Revised national estimates of emergency department visits for sepsis in the United States. Critical Care Medicine, 45(9), 1443-1449.

Wattanasit, P., & Khwannimit, B. (2021). Comparison the accuracy of early warning scores with qSOFA and SIRS for predicting sepsis in the emergency department. The American Journal of Emergency Medicine, 46, 284-288.

Wei, S., Xiong, D., Wang, J., Liang, X., Wang, J., & Chen, Y. (2023). The accuracy of the national early warning score 2 in predicting early death in prehospital and emergency department settings: A systematic review and meta-analysis. Annals of Translational Medicine, 11(2), 95. doi:10.21037/atm-22-6587