Benefit of Post-mastectomy Radiotherapy for Breast Cancer Patients with T1-2 and 1-3 Positive Axillary Lymph Node

Authors

  • Poomipat Bhumisawatdi Division of Head Neck and Breast Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Doonyapat Sa-nguanraksa Division of Head Neck and Breast Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University
  • Pornchai O-charoenrat Division of Head Neck and Breast Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University

Abstract

Background: Post-mastectomy irradiation is suggested in T1-2 and 1-3 positive axillary nodes. In Thailand, there is no consensus of radiotherapy in this group of patients.

Patients and Methods: Medical records of breast cancer patients with T1-T2, 1-3 axillary nodal metastasis and underwent modified radical mastectomy or total mastectomy with positive sentinel node biopsy were reviewed. Disease free survival (DFS) and overall survival (OS) were compared.

Results: There were 66 patients received radiotherapy and 92 patients did not receive radiotherapy. Survival analysis revealed that there was no significant difference in DFS and OS between the two groups. Subgroup analysis showed that radiotherapy in hormone receptor negative patients tended to result in better DFS.

Conclusion: The benefit of radiotherapy in T1-2 with 1-3 positive axillary nodes is not clear, however, selection of the patient to receive radiotherapy might result in better survival.

References

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Published

2018-06-28

How to Cite

1.
Bhumisawatdi P, Sa-nguanraksa D, O-charoenrat P. Benefit of Post-mastectomy Radiotherapy for Breast Cancer Patients with T1-2 and 1-3 Positive Axillary Lymph Node. Thai J Surg [Internet]. 2018 Jun. 28 [cited 2024 May 20];39(2):39-44. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/219935

Issue

Vol. 39 No. 2 (2018): April - June

Section

Original Articles

License

Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.