Results and Predictive Factors for Survival of Periampullary Cancer Patients at Uttaradit Hospital
Keywords:
Periampullary cancer, Result, Predictive factor, SurvivalAbstract
Introduction: Periampullary cancer is one of the major health concerns worldwide. Even though there are some attempts to work the disease out, the prognosis of periampullary cancer remains poor.
Objective: To study results and predictive factors for survival of periampullary cancer patients at Uttaradit Hospital. Patients and Methods: A long-term observational analytic study was done. Information of 82 patients diagnosed with periampullary cancer who received treatment at Uttaradit Hospital from October 2007 to October 2012 was gathered from the database of Department of Surgery, Uttaradit Hospital. The patients’ final status had been followed until September 2015. Descriptive statistics, Kaplan-Meier method and a Log-rank test were applied to analyze the information.
Results: Patients had an average age of 64.99 years and 52.44% of them were male. All patients had primary tumors located in places as follows: 56.09% at the head of pancreas and 39.02% at the ampulla of Vater. Pancreaticoduodenectomy (PD) was performed in 48.78% of the patients. The overall mortality rate was 53.66%. The median survival time was 2.75 years. The predictive factors were chronic alcohol drinking (p < 0.01) and PD operation (p < 0.05).
Conclusion: Chronic alcohol drinking and a PD operation have significant contribution to the survival of periampullary cancer patients.
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