Safety of Early Feeding after Mini-Incision Appendectomy
Randomized Controlled Trial
Keywords:
Appendectomy, Appendicitis, Early feeding, Mini-incision, Postoperative ileusAbstract
Introduction: Current evidence seems to suggest that early feeding can improve postoperative recovery after appendectomy. However, the safety of early feeding after mini-incision appendectomy (MOA) is still unclear, especially in complicated appendicitis. The main objective of this study was to assess the safety of early feeding in patients who underwent MOA in both simple and complicated acute appendicitis.
Materials and Methods: This study was an open-label, randomized controlled trial. We randomly allocated patients undergoing MOA to either the early feeding group (EF) or to a standard care group (SC). The primary outcome was postoperative ileus. Subgroup analysis of complicated appendicitis was done in this study.
Results: Patients in the EF group had a significantly shorter duration of postoperative ileus (mean difference 8.65 hours, SD = 3.93, p = 0.03) and time taken to tolerate a soft diet (mean difference 9.76 hours, SD = 4.08, p = 0.02). There was no significant difference in complications. In the subgroup analysis of complicated appendicitis, there was no significant difference in postoperative outcome between both groups.
Conclusion: Early feeding after MOA reduced postoperative ileus and the time taken to tolerate a soft diet without increased postoperative complications.
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