Upper Gastrointestinal Endoscopy Findings in Patients Presenting with Dyspepsia

Authors

  • Piyaporn Choomsri Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Wanichya Bumpenboon Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Yodying Wasuthit Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Chakkrapan Euanorasetr Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Preeda Sumritpradit Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Weerapat Suwanthunma Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
  • Panuwat Lertsithichai Department of Surgery, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand

Keywords:

upper gastrointestinal endoscopy, dyspepsia, H. pylori

Abstract

Objective: To determine the prevalence of important upper gastrointestinal (UGI) lesions in patients
with dyspepsia and to determine the associated risk factors.
Methods: A prospective cohort study on dyspeptic patients undergoing UGI endoscopy during the
period between May 2006 and October 2008 was conducted. A questionnaire was administered to all patients
who consented to participate in the study. Endoscopic findings were defined as important if lesions seen were
gastric or duodenal ulcers, moderate to severe gastritis, severe esophagitis, adenomatous polyps or cancer.
Histological examination results were obtained for patients who also underwent endoscopic biopsy.
Results: A total of 291 dyspeptic patients were enrolled. Only 19% (54/291) of patients had important
endoscopic lesions. No clinical findings including age and alarm symptoms were related to important
endoscopic lesions. In 132 patients, 23% (30/132) of the endoscopic biopsies showed evidence of H. pylori
infection. In patients with endoscope biopsy results, H. pylori infection was not associated with important
endoscopic findings.
Conclusion: Dyspeptic patients had a low prevalence of important endoscopic lesions. The presence of
these lesions could not be reliably predicted using clinical data and H. pylori infection status. Empirical antiacid
therapy was recommended as the initial screening therapeutic test prior to endoscopic evaluation for most
patients.

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Published

2010-03-31

How to Cite

1.
Choomsri P, Bumpenboon W, Wasuthit Y, Euanorasetr C, Sumritpradit P, Suwanthunma W, Lertsithichai P. Upper Gastrointestinal Endoscopy Findings in Patients Presenting with Dyspepsia. Thai J Surg [Internet]. 2010 Mar. 31 [cited 2022 Dec. 10];31(1). Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/227825

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