Primary Diffuse Large B-cell Lymphoma of the Prostate: A Case Report

Authors

  • Phitsanu Mahawong Division of Urology, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
  • Teerapon Amornvesukit Division of Urology, Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
  • Suchai Soontrapa Division of Urology, Department of Surgery,Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
  • Sanya Sukpanichnant Department of Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

Keywords:

Lymphoma, B-cell, Prostate

Abstract

Background: Primary malignant lymphoma of prostate is extremely rare.
Objective: The objectives are to report a case of primary lymphoma of the prostate, result of the
treatment and review of the literatures.
Case report: A 73-year-old Thai male initially presented with gross hematuria and acute urinary
retention. Abdominal computed tomography demonstrated a mass in left lobe of prostate gland. Diffuse large
B-cell lymphoma was diagnosed by transrectal prostatic biopsy and bone marrow staging was positive. The
patient underwent 6 cycles of chemotherapy resulting in complete remission on follow-up at 24 months after
diagnosis.
Conclusion: Although primary lymphoma of prostate gland is extremely rare, it should be included in
the differential diagnosis for all patients who present with lower urinary tract symptoms and/or hematuria.

References

1. Chu PG, Huang Q, Weiss LM. Incidental and concurrent
malignant lymphomas discovered at the time of
prostatectomy and prostate biopsy: a study of 29 cases. Am
J Surg Pathol 2005;29:693-9.

2. Bostwick DG, Iczkowski KA, Amin MB, et al. Malignant
lymphoma involving the prostate: report of 62 cases. Cancer
1998;83:732-8.

3. Yong RH, Srigley JR, Amin MB, Ulbright TM, Cubilla AL. Tumors
of the prostate gland, seminal vesicles, male urethra and
penis. Atlas of tumor pathology. Washington DC: Armed
Forces Institute of Pathology; 2000.

4. Choi WW, Yap RL, Ozer O, et al. Lymphoma of the prostate
and bladder presenting as acute urinary obstruction. J Urol
2003;169:1082-3.

5. Andreas S, Meletios D, William P, et al. Primary lymphoma of
the prostate: good outcome with doxorubicin-based
combination chemotherapy. J Urol 1995;153:1852-4.

6. Ghose A, Baxter-Smith DC, Eeles H, et al. Lymphoma of the
prostate treated with radiotherapy. Clin Oncol 1995 7:134.

7. Leung TW, Tung SY, Sze WK, et al. Primary non Hodgkin
lymphoma of the prostate. Clin Oncol 1997;9:264-6.

8. Sukpanichnant S. Lymphoma: diagnosis and knowledge in
hematopathology. Bangkok, Siriraj Medical Textbook Project;
2005.

9. Jaffe ES, Harris NL, Stein H, Vardiman JW. World Health
Organization Classification of Tumours. Pathology and
genetics of tumours of haematopoietic and lymphoma tissues.
Lyon, France: IARC Press; 2001.

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Published

2010-03-31

How to Cite

1.
Mahawong P, Amornvesukit T, Soontrapa S, Sukpanichnant S. Primary Diffuse Large B-cell Lymphoma of the Prostate: A Case Report. Thai J Surg [Internet]. 2010 Mar. 31 [cited 2024 Nov. 23];31(1). Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/227849

Issue

Vol. 31 No. 1 (2010): January - March

Section

Case Reports

License

Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.