Breast Biopsy: Accuracy of Core Needle Biopsy Compared with Excisional or Incisional Biopsy: A Prospective Study
Abstract
Objective: To determine the accuracy and complications of manual core needle breast biopsy compared with excisional or incisional biopsy.
Materials and Methods: Between October 2004-September 2005, core needle breast biopsy was performed in 92 women with suspicious malignancy of the breasts on physical examination. The mean age was 53.9 years (range 38-73 years). Mean tumor size was 3.1 cm (range 1.8-8.2 cm). Pathological findings of core needle biopsy were compared with excisional or incisional biopsy and procedural complications and treatment were noted.
Results: Ninety-two core needle biopsies were performed over the period. The histopathologic findings of core needle specimens correlated with those of excisional or incisional biopsy in 85 patients (92.4%). Invasive ductal carcinoma was diagnosed in 79 patients, benign lesion in 6 patients (4 fibroadenoma and 2 fibrocystic disease), with accuracy rate of 92 %, sensitivity of 92%, specificity of 100% and over all false-negative rate of 7.6% (7 in 92 patients).
Conclusions: In this study, core needle breast biopsy yielded an accuracy rate of 92% compared with excisional or incisional biopsy. There may be a slight higher risk of bleeding which may be related to the lack of breast compression during the procedure.
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