Advantages of Urgotul S,.S.D over Silver Sulfadiazine Cream in the Outpatient Management of Partial Thickness Burns
Keywords:
Silver sulfadiazine, Urgotul SSDTM, burn wound, wound infectionAbstract
Introduction: Topical application of silver sulfadiazine has been used in the treatment of partial thickness burns for many years, Pain during daily wound cleansing is the main problem. Urgotul SSD,TM a hydrocolloid dressing with silver sulfadiazine (SSD) has been reported to reduce infection and exhibit antimicrobial activity in burn wounds.
Objectives: The purpose of this study was to compare the efficacy of Urgotul SSDTM and 1% silver sulfadiazine for the treatment of partial thickness burn wounds.
Materials and Methods: We reviewed 70 patients who had partial thickness burn wound less than 15% total body surface area (TBSA%) and were treated at Siriraj out-patient burn clinic during July 2005-December 2006. All patients were divided into two groups: Urgotul SSDTM treated group (35 patients) and 1% silver sulfadiazine treated group (35 patients). Two patients were excluded; one was due to allergic reaction to silver sulfadiazine and another one in Urgotul SSDTM treated group was pregnant. The two groups were compared by the demographic data including age, gender, % total body surface area (TBSA) burn, % TBSA deep burn, as well as percent of wound infection, total cost of wound dressing, pain medication, level of pain and time of wound healing. There were no differences in demographic data of age, % TBSA burn, % wound infection and total treatment cost of burn wound care (US$ 52 ± 38 for Urgotul SSDTM versus US$ 45 ± 34 for silver sulfadiazine treated group),
Results: Time of wound closure was significantly shorter in Urgotul SSDTM treated group (10 ± 4 days in Urgotul SSDTM versus 12 ± 6 in 1% silver sulfadiazine treated group, p <0.05). Average pain scores and pain medication in Urgotul SSDTM treated group were significantly lower than in 1% silver sulfadiazine treated group (3 ± 1 versus 6 ± 2 respectively, p <0.05). All of the patients who developed wound infection responded well to targeted topical and oral antibiotic treatment.
Conclusions: We conclude that Urgotul SSDTM has advantages of reducing pain symptom, pain medication requirement, increased patient convenience due to decreased time of follow-up at out-patient burn clinic, limiting the frequency of replacement of the dressing at comparable total cost and incidence of burn wound infection. This study confirms the efficacy of Urgotul SSDTM in the treatment of partial thickness burn wound at out-patient clinic.
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