Adequacy of Lymph Node Harvested by Curative Intent Resection for Colorectal Cancer: Ramathibodi Experience
Keywords:
Lymph node, Curative intent, Colorectal cancerAbstract
Objective: Number of lymph node reported is main predictor of outcome in colorectal cancer. We review the adequacy of Iymph node harvested by curative intent resection of our colorectal cancer patients in one year period.
Materials and Methods: From January-December 2003, 138 colorectal cancer patients underwent curative intent operations. Thirty-seven patients were excluded. Patient demographic data, type of operation, number of lymph node harvested and tumor staging were obtained from chart reviewed. All tumors were staged by TNM staging system.
Results: From 101 patients, 52 colon and 49 rectal cancer cases were reviewed. Average number of lymph node harvested was 18.57. Left-sided resection and rectal operation had high percentage of Iymph node inadequacy. In node-negative cases, 25% of colon and 46% of rectal cancer had inadequate Iymph node harvested resulted in overall 36 % in this group were potentially understaged.
Conclusion: Right-sided colon resection is the only operation that has excellent result in terms of adequacy of lymph node harvest. Improvement of lymph node retrieved in left-sided colon resection and rectal resection will result in upstaging and improved patient outcome.
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