Risk Factors Predicting Morbidity and Mortality in Peptic Ulcer Perforation at Maharaj Nakorn Chiangmai Hospital

Authors

  • Choopong Sukpromson Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
  • Kittipan Rerkasem Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
  • Somsak Sumitsawan Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand

Abstract

Background: Peptic ulcer perforation (PUP) is one of the important problems in Maharaj Nakorn Chiangmai Hospital due to high morbidity and mortality. If the risk factors of these outcomes are identified, modification of these risk factors may improve the outcomes. This study was conducted to identify these risk factors.

Methods: Data of 203 patients with PUP admitted to Maharaj Nakorn Chiangmai Hospital from January 2001 to October 2004 were studied retrospectively. General health data and data of twelve relevant risk factors were collected. The risk factors were analyzed by chi-squared test.

Results: The overall morbidity rate was 21.2% and mortality rate was 12.8%. Risk factors significantly associated with high mortality were age over 60 years, patient with underlying diseases (hypertension, diabetes mellitus, COPD, renal insufficiency, CHF, IHD, CA lung), duration from abdominal pain to operation more than 12 hours, hypotension before surgery, perforated size larger than 0.5 cm, and severe degree of contamination. The mean hospital stay was 8.64 days and number of patients who stayed more than 8 days was 50 (24.6%). Risk factors significantly associated with increasing hospital stay of more than 8 days were similar to those predicting mortality.

Conclusion: This study showed clearly that the duration before operation and hypotension were associated with high mortality and morbidity. Surgeons should modify these risk factors before surgery or referral.

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Published

2006-06-30

How to Cite

1.
Sukpromson C, Rerkasem K, Sumitsawan S. Risk Factors Predicting Morbidity and Mortality in Peptic Ulcer Perforation at Maharaj Nakorn Chiangmai Hospital. Thai J Surg [Internet]. 2006 Jun. 30 [cited 2024 Dec. 23];27(2):68-73. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/242034

Issue

Vol. 27 No. 2 (2006): April - June

Section

Original Articles

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Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.