Reliability of Detecting Macrometastases in Sentinel Lymph Node in Breast Cancer Patients by Bivalued Section in Comparison to Serial Section

Authors

  • Capt Chinkrit Boonya-assadorn Department of Surgery, Phramongkutklao Hospital & College of Medicine, Bangkok
  • Lt Col Sukchai Sattaporn Department of Surgery, Phramongkutklao Hospital & College of Medicine, Bangkok
  • Lt Col Shinnawat Wisutthipaet Department of Surgery, Phramongkutklao Hospital & College of Medicine, Bangkok
  • Col Wichai Wassanasiri Department of Surgery, Phramongkutklao Hospital & College of Medicine, Bangkok
  • Maj Gen Suraphong Supaporn Department of Surgery, Phramongkutklao Hospital & College of Medicine, Bangkok
  • Capt Yuthapong Srikot Army Institute of Pathology, Phramongkutklao Medical Center, Bangkok
  • Lt Col Thawatchai Sillapiyodom Army Institute of Pathology, Phramongkutklao Medical Center, Bangkok

Abstract

Objectives: The aim of this study was to compare the reliability of bivalved section with serial section to detect the macrometastases in sentinel lymph node in breast cancer patients.

Materials and Methods: A total number of 40 patients were involved in the reliability study to detect the macrometastases in sentinel lymph node (SLN) in breast cancer patients in the Department of Surgery, Phramongkutklao Hospital & College of Medicine, between January 2000 and June 2004.

Results: Of 76 sentinel lymph nodes, 28 were positive and 48 were negative. In detecting SLN by dye direct injection with isosulfan blue, 42 out of 45 cases were identified, with an identification rate of 93.3% and with false negative (skip metastases) in 2 cases (4.76%). The negative SLN by bivalved section was then studied by serial section at 1 mm interval and dyed with H & E, whereby I node of micrometastases was encountered. However, when compared with previous slide, the micrometastases already existed. No additional metastases were encountered in other lymph nodes as well as in false negative lymph nodes.

Conclusions: This study revealed that there was no difference in detecting macrometastases of SLN by bivalved section and serial section. The reliability in detecting the macrometastases by bivalved section in this study is 100%. However, the numbers of the sample are too small for conclusion and further studies with more sample size are required.

References

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Published

2005-09-30

How to Cite

1.
Boonya-assadorn CC, Sattaporn LCS, Wisutthipaet LCS, Wassanasiri CW, Supaporn MGS, Srikot CY, Sillapiyodom LCT. Reliability of Detecting Macrometastases in Sentinel Lymph Node in Breast Cancer Patients by Bivalued Section in Comparison to Serial Section. Thai J Surg [Internet]. 2005 Sep. 30 [cited 2024 Apr. 28];26(3):78-81. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/242140

Issue

Vol. 26 No. 3 (2005): July - September

Section

Original Articles

License

Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.