Retroperitoneal Approach for Surgical Treatment of Infected Pancreatic Necrosis

Authors

  • Sukanya Sriussadaporn Department of Surgery, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

Abstract

Infected pancreatic necrosis is the most severe form of acute pancreatitis. Without proper management, the mortality rate is very high. Surgical debridement of the infected necrotic tissue and drainage are mainstays of therapy. Several methods of surgical debridement and drainage have been advocated. Various techniques of transperitoneal necrosectomy and drainage are among the recommended surgical treatment. However, reoperation for repeated debridements is usually required and some complications related to the transperitoneal approach may be encountered. The retroperitoneal approach is an alternative which has been previously proposed and reported with satisfactory outcome.

A 42-year old male with infected pancreatic necrosis who underwent repeated surgical removal of the necrotic tissue by retroperitoneal approach via a flank incision is presented. The patient had daily debridement for 14 consecutive days and then changed to once every 2 days with 20 re-operations overall by the retroperitoneal approach during this admission. Massive amounts of necrotic materials were obtained during the early period and decreased to a minimal amount until surgery was discontinued and replaced by daily irrigation of the retroperitoneal area via a tube drain. The patient's clinical condition gradually improved with the flank wound progressively decreasing in size and eventually closing spontaneously. He was discharged on the 80th day after the first operation without evidence of pancreatic exocrine or endocrine insufficiency.

The advantage of this retroperitoneal approach is the avoidance of disturbing the intraperitoneal hollow viscus and subsequent formation of gastrointestinal fistulas. Furthermore, early enteric feeding can be initiated and patient's recovery is enhanced by improved nutritional status.

References

1. Carter CR, McKay CJ, Imrie CW. Percutaneous necrosectomy and sinus tract endoscopy in the management of infected pancreatic necrosis: an initial experience. Ann Surg 2000; 232:175-80.

2. Beger HG, Buchler M, Bittner R, Block S, Nevalainen T, Roscher R. Necrosectomy and postoperative local lavage in necrotizing pancreatitis. Br J Surg 1988;75: 207-12.

3. Allardyce DB. Incidence of necrotizing pancreatitis and factors related to mortality. Am J Surg 1987; 154: 295-9.

4. Rau B, Steinbach G, Gansuage F, Mayer JM, Grunert A, Beger HG. The potential role of procalcitonin and interleukin 8 in the prediction of infected necrosis in acute pancreatitis. Gut 1997; 41: 832-40.

5. Bradley EL. Management of infected pancreatic necrosis by open drainage. Ann Surg 1987; 206: 542-50.

6. Rattner DW, Legermate DA, Lee MJ, Mueller PR, Warshaw AL. Early surgical debridement of symptomatic pancreatic necrosis is beneficial irrespective of infection. Am J Surg 1992;163: 105-10.

7. Branum G, Galloway J, Hirchowitz W, Fendley M, Hunter J. Pancreatic necrosis: results of necrosectomy, packing, and ultimate closure over drains. Ann Surg 1998; 227: 870-7.

8. Tsiotos GG, Luque-de Leon E, Soreide JA, Bannon MP, Zietlow SP, Baerga-Varela Y, et al. Management of necrotizing pancreatitis by repeated operative necrosectomy using a Zipper technique. Am J Surg 1998;175:91-8.

9. Gerzof SG, Banks PA, Robbins AH, Johnson WC, Spechler SJ, Wetzner SM, et al. Early diagnosis of pancreatic infection by computed tomography-guided aspiration, Gastroenterology 1987;93:1315-20.

10. London NJ, Neoptolemos JP, Lavelle J, Bailey I, James D. Serial computed tomography scanning in acute pancreatitis: a prospective study. Gut 1989: 30: 397-403.

11. Ramesh H, Prakash K, Lekha V, Jacob G, Venugopal A, Are some cases of infected pancreatic necrosis treatable without intervention? Dig Surg 2003; 20: 296-300.

12. Uhl W, Warshaw A, Imrie C, Bassi C, McKay CJ, Lankisch PG, et al. IAP guidelines for the surgical management of acute pancreatitis. Pancreatology 2002; 2: 565-73.

13. Widdison AL, Karanjia ND, Pancreatic infection complicating acute pancreatitis. Br J Surg 1993; 80: 148-54.

14. Holden JL, Burne TV, Rosoff L Sr, Pancreatic abscess following acute pancreatitis. Arch Surg 1976; 111: 858-61.

15. Aranha GV, Printz RA, Greenlee HB. Pancreatic abscess: an unresolved surgical problem, Am J Surg 1982; 144: 534-8.

16. Camer SJ, Tan EG, Warren KW, Braasch JW. Pancreatic abscess. A critical analysis of 1 13 cases. Am J Surg 1975; 129:426-31.

17. Ranson JH, Spencer FC. Prevention, diagnosis, and treatment of pancreatic abscess. Surgery 1977;82: 99-106.

18. Frey CF, Lindenauer SM, Miller TA. Pancreatic abscess. Surg Gynecol Obstet 1979; 149: 722-6,

19. Becker JM, Pemberton JH, DiMagno EP, IIstrup DM, Mcllrath DC, Dozois RR. Prognostic factors in pancreatic abscess. Surgery 1984; 96: 455-61.

20. Wertheimer MD, Norris CS. Surgical management of necrotizing pancreatitis. Arch Surg 1986; 121: 484-7.

21. Garcia-Sabrido JL, Tallado J, Christou NV, Polo JR, Valde cantos E. Treatment of severe intra-abdominal sepsis and or necrotic foci by open-abdomen approach. Arch Surg 1988; 123:152-6.

22. Schein M, Hirshberg A, Hasmonai M. Current surgical management of severe intraabdominal infection. Surgery 1992;112:489-96.

23. Rau B, Uhl W, Buchler MW, Beger HG. Surgical management of infected necrosis. World J Surg 1997; 21: 155-61.

24. Larvin M, Chalmers AG, Robinson PJ, MCMahon MJ. Debridement and close cavity irrigation for the treatment of pancreatic necrosis. Br J Surg 1989; 76: 465-71.

25. Bassi C, Vesentini S, Nifosi F, Girelli R, Falconi M, Elio A, et al. Pancreatic abscess and other pus-harboring collections related to pancreatitis: a review of 108 cases. World J Surg 1990;14:505-12.

26. Cuschieri A. Pancreatic necrosis: pathogenesis and endoscopic management. Semin Laparosc Surg 2002; 9:54-63.

27. Ammori BJ. Laparoscopic transgastric pancreatic necrosectomy for infected pancreatic necrosis. Surg Endosc 2002; 16: 1362.

28. Adamson GD, Cuschieri A. Multimedia article. Laparoscopic infracolic necrosectomy for infected pancreatic necrosis. Surg Endosc 2003; 17: 1675.

29. Zhou ZG, Zheng YC, Shu Y, Hu WM, Tian BL, Li QS, et al. Laparoscopic management of severe acute pancreatitis. Pancreas 2003;27: 46-50.

30. Castellanos G, Pinero A, Serrano A, Parrilla P. Infected pancreatic necrosis: translumbar approach and management with retroperitoneoscopy. Arch Surg 2002; 137:1060-3.

31. Halkic N, Pezzetta E, Abdelmoumene A, Corpataux JM. Indications and results of retroperitoneal Iaparostomy in the treatment of infected acute necrotizing pancreatitis. Minerva Chir 2003; 58:97-9.

32. Villazon A, Villazon O, Terrazas F, Rana R, Retroperitoneal drainage in the management of the septic phase of severe acute pancreatitis. World J Surg 1991; 15: 103-8.

33. Fagniez PL, Rotman N, Kracht M. Direct retroperitonea approach to necrosis in severe acute pancreatitis. Br J Surg 1989;76:264-7.

34. Van Vyve E, Reynaert M, Lengele B, Pringot JT, Otte JB Kestens PJ. Retroperitoneal laparostomy: a surgical treatment of pancreatic abscesses after an acute necrotizing pancreatitis. Surgery 1992; 111: 369-75.

Downloads

Published

2005-03-31

How to Cite

1.
Sriussadaporn S. Retroperitoneal Approach for Surgical Treatment of Infected Pancreatic Necrosis. Thai J Surg [Internet]. 2005 Mar. 31 [cited 2024 Dec. 23];26(1):22-6. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/242250

Issue

Section

Original Articles