Acute Appendicitis: A 5-year Review of Histopathology and Clinical Presentation
Abstract
Background: Appendicitis is one of the most common causes of acute abdominal pain. Study of diagnostic accuracy and pathological correlation aiming to reduce not only late complications but also the rate of negative appendectomy had been studied worldwide.
Patients and Methods: The diagnostic accuracy and important clinical presentations of acute appendicitis in 449 patients who underwent appendectomy in a 5-year period from 1996 to 2001 were retrospectively studied. The pathological reports were reviewed and grouped into Group I, acute appendicitis with or without perforation and Group II, no acute inflammation of appendix. Clinical information of age, sex, body temperature, and laboratory findings were analyzed by Chi-square test and p<0.05 was considered statistically significant.
Results: There were 396 cases in Group I (88.2%) and 53 cases in Group II (11.8%). Male and children less than 10 years old were the significant factors related to acute appendicitis (p<0.05). Increased neutrophilic ratio (neutrophil >75%) was significantly associated with acute appendicitis (p<0.05) especially in the range of 80-85%. There were no significant association between acute appendicitis and body temperature, WBC count, Hct, and urinary WBC.
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