Lymphatic Mapping and Sentinel Node Biopsy in Breast Cancer : Current View

Authors

  • P. Purasiri Department of Surgery, Samitivej Srinakarin Hospital, Bangkok 10250, Thailand.

Abstract

                 Axillary lymph node disection for breast cancer generally is accepted for its staging and prognostic value, but the extent of dissection remains controversial. Blind Iymph node sampling may miss some nodal metastases and axillary lymph node dissection may result in lymphedema. Sentinel Iymph node biopsy is a recently developed, minimally invasive technique for staging the axilla in patients with early breast cancer. Lymphatic mapping techniques have the potential of changing the standard of surgical care of breast cancer patients and that the technique will avoid the morbidity associated with more extensive axillary dissection. A wide range of different methods and materials has been employed for lymphatic mapping. Sentinel lymph node biopsy is a valid technique in breast cancer management, which can yield valuable axillary staging information. The technique can enhance staging accuracy, and with further refinements and experience may replace the role of axillary lymph node dissection.

References

1. Kissin MW, Querci della Rovere G, Easton D, Westbury G. Risk of lymphoedema following the treatment of breast cancer. Br J Surg 1986; 73: 580-4.

2. Ivens D, Hoe AL, Podd TJ, Hamilton CR, Taylor I, Royle GT. Assessment of morbidity from complete axillary dissection. Br J Cancer 1992; 66:136-8.

3. Carter CL, Allen C, Henson DE. Relation of tumour size, lymph node status and survival in 24,740 breast cancer cases. Cancer 1989:63: 181-7.

4. Guiliano AE, Barth AM, Spivack B, Beitsch PD, Evans SW. Incidence and predictors of axillary metastasis in Th carcinoma of the breast. J Am Coll Surg 1996; 183: 185-9.

5. Graversen HP, Blicher-Toft M, Anderson JA, Zedeler K. Breast cancer: risk of axillary recurrence in node-negative patients following partial dissection of the axilla. Eur J Surg Oncol 1988; 14:407-12.

6. Benson EA, Thorogood J. The effect of surgical technique on local recurrence rates following mastectomy. Eur J Surg Oncol 1986; 12:267-71.

7. Cabanas RM. An approach for the treatment of penile carcinoma. Cancer 1977; 39: 456-66.

8. Morton DL, Wen D-R, Wong JH, Econnmou Js, Cagle LA, Storm FK et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 1992; 127: 392-9.

9. Alex JC, Weaver DL, Fairbank JT, Rankin BS, Krag DN. Gamma probe guided lymph node localisation in malignant melanoma. Surg Oncol 1993; 2: 303-8.

10. Nemoto T, Vana J, Bedvani RN, Baker HW, McGregor FH, Murphy GP. Management and survival of female breast cancer: results of a national survey by the American College of Surgeons. Cancer 980; 45: 2917-24.

11. McCready DR, Hortobagyi GN, Kau SW, Smith CL, Buzdar AU, Balch CM. The prognostic significance of lymph node metastases after preoperative chemotherapy for locally advanced breast cancer. Arch Surg 1989; 124: 21-5.

12. Rosen PP, Lesser ML, Kinne DW, Beattie EJ. Discontinuous or "skip" metastases in breast carcinoma: analysis of 1,228 axillary dissections. Ann Surg 1983; 197: 276-83.

13. Van Lanket M, Goor C, Sacre R, et al. Pattern of axillary lymph node metastasis in breast cancer. Am J Clin Oncol 1995;18: 267-72.

14. Giuliano AE, Jones RC, Brennan M, Statman R. Sentinel lymphadenectomy in breast cancer. J Clin Oncol 1997; 15:2345-50.

15. International (Ludwig) Breast Cancer Study Group. Prognostic importance of occult axillary lymph node micrometastases from breast cancers. Lancet 1990; 335:1565-8.

16. Neville AM, Price K, Gelber RD, Goldhirsch A. Axillary node micrometastases and breast cancer. Lancet 1991;337: 1110.

17. Hainesworth PJ, Tjandra JJ, Stillwell RG, et al. Detection and significance of occult metastases in node negative breast cancer. Br J Surg.1993; 80: 459-63.

18. McGuckin MA, Cummings MC, Walsh MD, Hohn BG, Bennett IC, Wright RG. Occult axillary node metastases in breast cancer: their detection and prognostic significance. Br J Cancer 1996;73: 88-95.

19. Lacour J, Bucalossi P, Cacers E, Jacobelli G, Koszarowski T, Le M et al. Radical mastectomy versus radical mastectomy plus internal mammary dissection. Cancer 1976; 37:206-14.

Downloads

Published

2000-03-31

How to Cite

1.
Purasiri P. Lymphatic Mapping and Sentinel Node Biopsy in Breast Cancer : Current View. Thai J Surg [Internet]. 2000 Mar. 31 [cited 2024 Dec. 23];21(1):13-6. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/243359

Issue

Section

Original Articles