Clinical and Oncological Outcomes of Laparoscopic Colorectal Surgery for Colorectal Cancer at Trang Hospital
Keywords:
Laparoscopic colorectal surgery, Colorectal cancer, Short-term outcomesAbstract
Background & Objective: Colorectal cancer is the third most common cancer in both men and women in Thailand and around the world. Laparoscopic colectomy (LC) has gained wide acceptance as a curative procedure for colorectal cancer treatment. However, in Thailand, LC is practiced in high-volume hospitals. A predisposing factor for a higher morbidity rate of LC was male gender. The primary aim of this retrospective study was to review the clinical and short-term oncological outcomes of laparoscopic colectomy for colorectal cancer from the preliminary first-hand experience of a general surgeon performing LC at Trang Hospital. The secondary aim was to test the hypothesis that male gender has no impact on the clinical and short-term oncological outcomes.
Patients and Methods: A retrospective study was conducted at Trang hospital in all colorectal cancer patients who underwent laparoscopic colorectal surgery between August 2017 and December 2019. Patient characteristics, perioperative, pathologic and short-term oncological outcomes were reported and compared between the genders.
Results: In 19 colorectal cancer patients who underwent laparoscopic colorectal resection, there was a significant difference in tumor size between the men and women (p = 0.049) but no differences in perioperative outcomes between the two genders (p > 0.05). The overall conversion rate was 26%, the intraoperative complication rate was 5% and the postoperative complication rate was 16%. The mean follow-up period was 29 ± 11 months. There were no differences in the disease-free survival (DFS) (67% vs. 90%; p = 0.224) and overall survival (OS) (78% vs. 100%; p = 0.125) between men and women. The 2-year DFS and OS of all patients were 83% and 89%, respectively.
Conclusion: General surgeons can perform laparoscopic colorectal resection effectively and safely with acceptable outcomes. Male gender has no impact on the outcomes of laparoscopic colorectal resection in patients with colorectal cancer.
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