Clinical Experience with Major Hepatic Resections in Ramathibodi Hospital
Keywords:
Hepatectomy, Morbidity, Mortality, SurvivalAbstract
During 5 years and 10 months period from January 1, 1992 to October 31, 1997, 118 major hepatic resections were performed and 96 medical records were available for retrospective review. There were 63 males and 33 females. Age ranged from 25 to 84 years (average 53.73 years).
Indications for surgery were 43 hepatocellular carcinomas,36 cholangiocarcinomas, 10 metastatic cancers, 2 sarcomas and 5 benign lesions. Among 96 operations, there were 43 right lobectomies, 34 left lobectomies, 3 right trisegmentectomies, 9 left lateral segmentectomies, and 7 other segmentectomies. There were 54 operative complications from 29 patients (30.2%). Operative mortality was 8.3% (8 mortality cases). Overall 1 and 3 years survival was 71.05% and 52.93% respectively. The mean survival was 3.25 years. The morbidity, mortality, and long term survival of major hepatic resection in Ramathibodi hospital were comparable to other reported series.
References
1. Starzl TE, Bell RH, Beart RW, Putnam CW. Heparic trisegmentectomy and liver resection. Surg Gynecol Obstet 1975;141:429-32.
2. Petrelli Nu, Nambisan RN, Herrera L, Mittleman A. Hepatic resection for isolated metastasis from colorectal carcinoma. Am J Surg 1985; 149:205-9.
3. Thompson HH, Tompkins RK, Longmire WP. Major hepatic resection: A 25 - year experience. Ann Surg 1983: 197:375-85.
4. Iwatsuri S, Shaw BW , Starzl TE, Experience with 150 liver resection. Ann Surg 1983; 197:247-53.
5. Nonami T, Harada A, Kurokawa T, Nakao A , Taragi H. Hepatic resection for hepatocellular carcinoma. Am J Surg 1997;173 (4):288-91.
6. Pichlmayr R, Weimann A, Klempnauer J, OldhaferKJ, Maschek H, Tusch G, Ringe B. Surgical treatment of proximal bile duct cancer. A single - center experience. Ann Surg 1996; 224 (5):628-38.
7. Blumgart LH, Drury JK, Wood CB. Hepatic resection for trauma, tumour and biliary obstruction. Br J Surg 1979; 66:762-9.
8. Sitzmann JV, Oreene Ps. Perioperative predictors of morbidity following hepatic resection for neoplasm: A multivariate analysis of a single surgeon experience with 105 patients. Ann Surg 1994; 219 (1):13-7.
9. Miyagawa S, Makuuchi M, Kawasaki S, Kakazu T, Criteria for safe hepatic resection. Am J Surg 1995; 169:589-94.
10. Bismuth H. Surgical anatomy and anatomical surgery of the liver. World J Surg 1982; 6:3-9.
11. Thompson JN, Gibson R, Cerniak A, Blumgart LH. Focal liver lesions: a plan for management. Br Med J 1985; 290:1643-4.
12. Maruuchi M, Mori T, Gunven P, et al. Safety of hemihepatic vascular occlusion during resection of the liver. Surgery 1987; 164:155-6.
13. Makuuchi M, Takayama T, Gunven P, et al. Restrictive versus liberal blood transfusion policy for hepatectomies in cirrhotic patients. World J Surg 1989: 13:644-8.
14. Scheele J, Stangle R, Altendore - hofmanna. Hepatic metastasis from colorectal carcinoma: Impact of surgical resection on the natural history. Br J Surg 1990; 77:1241-6.
15. Al-Hadeedi S, Choi TK, Wong J. Extended hepatectomy for hepatocellular carcinoma. Br J Surg 1990; 77:1247-50.
16. Uttaravichien T. Cholangiocaroinoma: Srinagarind Hospital experience proceedings In: Association of Surgeons of South-east Asia.6th Biennial General Scientific Meeting. February 8-13, 1987, Bangkok : Association of Surgeons Southeast Asia,1987:9-10.
17. Nimura y, Hayakawa N, Kamiya J, Maede s, Rondo S, Yasui A, Shionoya S. Combined portal vein and liver resection for carcinoma of the biliary tract . Am J Surg 1991; 78(6):727-31
18. Tsuzuki T, Ogata Y, Lida S, Nakanishi l, Takanaka Y, Yoshii H. Carcinoma of the bifurcation of the hepatic duct. Arch Surg. 1983:118:1147-51.
19. NaguchiT, Kawarada Y, Kita gawa M, to F, Sakurai H, Machishi H, Yamagiwa K, Yokoi H, Mizumoto R. Clinicopathologic factors influencing the long-term prognosis following hepatic resection for large hepatocellular carcinoma more than 10 cm in diameter. Semin Oncol 1992; 24 (suppl6): S 6-7-1.
20. Tani M, Edamoto Y, Kawai S, Kobori O, Hayashis, Hanada K. Results of 90 consecutive hepatectiomies for hepatocellular carcinoma : A multivariate analysis of survival, Semin Oncol 1997; 24 (suppl6) : S 6-1-6.
21. Yamanara N, Oramoto E, Toyosara A, et al. Prognostic factors after hepatectomy for hepatocellular carcinomas: A univariate and multivariate analysis. Cancer 1990; 66(5): 1104-10.
22. Fortner JG, Kim DK, Maclean BJ , Barrett MK, IwatsukiS, Turnbull AD, Howland WS, Beattie EJ. Major hepatic resection for neoplasia. Ann Surg 1978; 158 (3):363-9.
23. Starzl TE, Iwatsuki s, Shaw BW Jr et al. Left hepatic trisegmentectomy. Surg Gynecol Obstet 1982:155:21-7.
24. Lin TY, Recent advances in technique of hepatic lobectomy and results of surgical treatment for primary carcinoma of the liver. Prog Liver Dis 1976; 5:668-82.
25. Wu M, Chen H, Zhang k, et al. Primary hepatic carcinoma resection over 18 year, Chinese Med J 1980; 93:723-8.
26. Pestana C, Reitemeier RJ. Moertel CG, et al. The natural history of carcinoma of the colon and rectum, Am J Surg 1955;90:704-16.
27. Pack GT, Brasfield RD. Metastatic cancer of the liver the clinical problem and its management. Am J Surg 1955;90:704-16.
28. Attiyeh FF, Wanebo HJ, Stearns MW. Hepatic resection for metastases from colorectal cancer. Dis Colon Rectum 1978;21:160-2.
29. Adson MA. Hepatic metastases. Dis Colon Rectum 1979; 22:366-9.
30. Taylor M, Forster J, Langer B, Taylor BR, Greig PD, Mahut C, A study of prognostic factors for hepatic resection for colorectal metastases, Am J Surg 1998; 173:467-71.
31. Cady B, Jenkil RL, Steele GD, Lewis WD, Stone MD, Mc Dermott WV, Jessup JM, Bothe A, Lalor P, Bovett L, Lavin P, Linehan DC, Surgical margin in hepatic resection for colorectal metastasis; A criteria and improvable determinant of outcome, Ann Surg 1998;227:566-71.
32. Fortner JG, Maclean BJ, KimDK, et al. The seventies evolution in liver surgery for cancer. Cancer 1981; 47:2162-6.
33. Adson MA, Vanheerden JA. Major hepatic resections for metastatic colorectal cancer. Ann Surg 1980; 191:576-89
34. Bengmark S, Halfstrom L, Jeppsson B, et al. Metastatic disease in the liver from colorectal cancer : An appraisal of liver surgery. World J Surg 1982; 6:61-5.
35. Wilson SM, Adson MA, Surgical treatment of hepatic metastases from coloreotal cancers. Arch Surg 1976; 111:330-4.
36. Vauthey JN, Klimstra D, Franceschi D, Tao Y MA, Fortner J, Blumgart L, Brennan M, Factors affecting long-term outcome after hepatic resection for hepatocellular carcinoma. Am J Surg 1995; 169:28-35.
2. Petrelli Nu, Nambisan RN, Herrera L, Mittleman A. Hepatic resection for isolated metastasis from colorectal carcinoma. Am J Surg 1985; 149:205-9.
3. Thompson HH, Tompkins RK, Longmire WP. Major hepatic resection: A 25 - year experience. Ann Surg 1983: 197:375-85.
4. Iwatsuri S, Shaw BW , Starzl TE, Experience with 150 liver resection. Ann Surg 1983; 197:247-53.
5. Nonami T, Harada A, Kurokawa T, Nakao A , Taragi H. Hepatic resection for hepatocellular carcinoma. Am J Surg 1997;173 (4):288-91.
6. Pichlmayr R, Weimann A, Klempnauer J, OldhaferKJ, Maschek H, Tusch G, Ringe B. Surgical treatment of proximal bile duct cancer. A single - center experience. Ann Surg 1996; 224 (5):628-38.
7. Blumgart LH, Drury JK, Wood CB. Hepatic resection for trauma, tumour and biliary obstruction. Br J Surg 1979; 66:762-9.
8. Sitzmann JV, Oreene Ps. Perioperative predictors of morbidity following hepatic resection for neoplasm: A multivariate analysis of a single surgeon experience with 105 patients. Ann Surg 1994; 219 (1):13-7.
9. Miyagawa S, Makuuchi M, Kawasaki S, Kakazu T, Criteria for safe hepatic resection. Am J Surg 1995; 169:589-94.
10. Bismuth H. Surgical anatomy and anatomical surgery of the liver. World J Surg 1982; 6:3-9.
11. Thompson JN, Gibson R, Cerniak A, Blumgart LH. Focal liver lesions: a plan for management. Br Med J 1985; 290:1643-4.
12. Maruuchi M, Mori T, Gunven P, et al. Safety of hemihepatic vascular occlusion during resection of the liver. Surgery 1987; 164:155-6.
13. Makuuchi M, Takayama T, Gunven P, et al. Restrictive versus liberal blood transfusion policy for hepatectomies in cirrhotic patients. World J Surg 1989: 13:644-8.
14. Scheele J, Stangle R, Altendore - hofmanna. Hepatic metastasis from colorectal carcinoma: Impact of surgical resection on the natural history. Br J Surg 1990; 77:1241-6.
15. Al-Hadeedi S, Choi TK, Wong J. Extended hepatectomy for hepatocellular carcinoma. Br J Surg 1990; 77:1247-50.
16. Uttaravichien T. Cholangiocaroinoma: Srinagarind Hospital experience proceedings In: Association of Surgeons of South-east Asia.6th Biennial General Scientific Meeting. February 8-13, 1987, Bangkok : Association of Surgeons Southeast Asia,1987:9-10.
17. Nimura y, Hayakawa N, Kamiya J, Maede s, Rondo S, Yasui A, Shionoya S. Combined portal vein and liver resection for carcinoma of the biliary tract . Am J Surg 1991; 78(6):727-31
18. Tsuzuki T, Ogata Y, Lida S, Nakanishi l, Takanaka Y, Yoshii H. Carcinoma of the bifurcation of the hepatic duct. Arch Surg. 1983:118:1147-51.
19. NaguchiT, Kawarada Y, Kita gawa M, to F, Sakurai H, Machishi H, Yamagiwa K, Yokoi H, Mizumoto R. Clinicopathologic factors influencing the long-term prognosis following hepatic resection for large hepatocellular carcinoma more than 10 cm in diameter. Semin Oncol 1992; 24 (suppl6): S 6-7-1.
20. Tani M, Edamoto Y, Kawai S, Kobori O, Hayashis, Hanada K. Results of 90 consecutive hepatectiomies for hepatocellular carcinoma : A multivariate analysis of survival, Semin Oncol 1997; 24 (suppl6) : S 6-1-6.
21. Yamanara N, Oramoto E, Toyosara A, et al. Prognostic factors after hepatectomy for hepatocellular carcinomas: A univariate and multivariate analysis. Cancer 1990; 66(5): 1104-10.
22. Fortner JG, Kim DK, Maclean BJ , Barrett MK, IwatsukiS, Turnbull AD, Howland WS, Beattie EJ. Major hepatic resection for neoplasia. Ann Surg 1978; 158 (3):363-9.
23. Starzl TE, Iwatsuki s, Shaw BW Jr et al. Left hepatic trisegmentectomy. Surg Gynecol Obstet 1982:155:21-7.
24. Lin TY, Recent advances in technique of hepatic lobectomy and results of surgical treatment for primary carcinoma of the liver. Prog Liver Dis 1976; 5:668-82.
25. Wu M, Chen H, Zhang k, et al. Primary hepatic carcinoma resection over 18 year, Chinese Med J 1980; 93:723-8.
26. Pestana C, Reitemeier RJ. Moertel CG, et al. The natural history of carcinoma of the colon and rectum, Am J Surg 1955;90:704-16.
27. Pack GT, Brasfield RD. Metastatic cancer of the liver the clinical problem and its management. Am J Surg 1955;90:704-16.
28. Attiyeh FF, Wanebo HJ, Stearns MW. Hepatic resection for metastases from colorectal cancer. Dis Colon Rectum 1978;21:160-2.
29. Adson MA. Hepatic metastases. Dis Colon Rectum 1979; 22:366-9.
30. Taylor M, Forster J, Langer B, Taylor BR, Greig PD, Mahut C, A study of prognostic factors for hepatic resection for colorectal metastases, Am J Surg 1998; 173:467-71.
31. Cady B, Jenkil RL, Steele GD, Lewis WD, Stone MD, Mc Dermott WV, Jessup JM, Bothe A, Lalor P, Bovett L, Lavin P, Linehan DC, Surgical margin in hepatic resection for colorectal metastasis; A criteria and improvable determinant of outcome, Ann Surg 1998;227:566-71.
32. Fortner JG, Maclean BJ, KimDK, et al. The seventies evolution in liver surgery for cancer. Cancer 1981; 47:2162-6.
33. Adson MA, Vanheerden JA. Major hepatic resections for metastatic colorectal cancer. Ann Surg 1980; 191:576-89
34. Bengmark S, Halfstrom L, Jeppsson B, et al. Metastatic disease in the liver from colorectal cancer : An appraisal of liver surgery. World J Surg 1982; 6:61-5.
35. Wilson SM, Adson MA, Surgical treatment of hepatic metastases from coloreotal cancers. Arch Surg 1976; 111:330-4.
36. Vauthey JN, Klimstra D, Franceschi D, Tao Y MA, Fortner J, Blumgart L, Brennan M, Factors affecting long-term outcome after hepatic resection for hepatocellular carcinoma. Am J Surg 1995; 169:28-35.
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Published
1998-09-30
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Wilasrusmee C, Chuphongphairot M, Kanchanapanchaphol S. Clinical Experience with Major Hepatic Resections in Ramathibodi Hospital. Thai J Surg [Internet]. 1998 Sep. 30 [cited 2024 Dec. 24];19(3):105-10. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/250036
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