The Immune Response : A tale of three signals

Authors

  • Philip F. Halloran Division of Nephrology, Department of Medicine, University of Alberta

Abstract

                An understanding of the molecular processes in allograft rejection should be the framework for understanding transplantation and immuno-suppression. For those who would understand the scientific basis of the phenomena that occur in clinical transplantation, it is essential to develop a model of the overall function of the immune response particularly identifying the essential and non-redundant steps in the immune response; and to determine how the immune suppressive interventions operate on this response.  This will be a dynamic view, which will incorporate new information continuously as it emerges from basic research and clinical experience.

                The final test of any of these views is how well it predicts clinical events, and how well it leads to successful applications in the clinic.

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Published

1996-12-30

How to Cite

1.
F. Halloran P. The Immune Response : A tale of three signals . Thai J Surg [Internet]. 1996 Dec. 30 [cited 2024 Dec. 24];17(4):164-6. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/250112

Issue

Vol. 17 No. 4 (1996): October - December

Section

Special Article

License

Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.