The Role of Somatostatin and Somatostatin Analogue in Surgical Practice
Keywords:
Somatostatin, Somatostatin AnalogueAbstract
Somatostatin และ somatostatin analogue มีบทบาทเพิ่มขึ้นเรื่อยๆ ในศัลยศาสตร์ บทฟื้นฟูวิซาการนี้ เขียนขึ้นโดยมีวัตถุประสงค์เพื่อให้ศัลยแพทย์ได้เช้าใจถึงสรีรวิทยา เภสัชวิทยา ข้อบ่งชี้ และบทบาทต่างๆ ของสารกลุ่มนี้ รวมทั้งได้สรุปผลการศึกษาต่างๆ ที่เกี่ยวกับการนำสารกลุ่มนี้มาใช้ในผู้ป่วยศัลยกรรม เพื่อเป็นพื้นฐานให้ ศัลยแพทย์ใช้เป็นหลักในการพิจารณาใช้ในผู้ป่วยต่อไป
References
1. Brazeau P, Vale W, Burgus R, et al. Hypothalamic polypeptide that inhibits the secretion of immuno- reactive pituitary growth hormone. Science 1973;179:77-79.
2. Praydayrol L, Jomvall H, Mutt V, Ribet A. N-terminally extended somatostatin : The primary structure of somatostatin-28. FEBS Lett 1980;109:55-58.
3. Francis BH, Baskin DG, Saunders DR, et al. Distribution of somatostatin-14 and somatostatin-28 gastrointestinal-pancreatic cells of rats and humans. Gastroenterology 1990;99:1283-1291.
4. Hildebrand P, Ensinck JW, Gyr K, et al. Is somatostatin-28 a physiologic regulator of gastric acid production in man ? Gastroenterology 1994; 103:240-247.
5. Luft R, Efendic S, Hokfelt T. Somatostatin both hormone and neurotransmitter? Diabetologia 1978; 14: 1-13.
6. McNeillis EL, Bausher LP. Stimulatory and inhibitory cyclin AMP responses in rabbit ciliary processes after cervical ganglionectomy. Curr Eye Res 1991; 10: 399-407.
7. Kraicer J, Spence JW. Release of growth hormone from purified somatotrophs : use of high K+ and the ionophore A23187 to elucidate interrelations among Cat+ adenosine 3,5 monophosphate and somatostatin. Endocrinology 1981; 108:651-657.
8. Bauer W, Briner U, Doepfner W, et al. Octreotide : a very potent and selective octapeptide analogue of somatostatin with prolonged action. Life Sci 1982;31:1133-1140
9.Meier RF, Gyr KE. Somatostatin : characterization and the role of analogues. Dig Surg 1994; 11:433-437.
10. Lucey MR, Yamada T. Biochemistry and physiology of gastrointestinal somatostatin. Dig Dis Sci 1989; 34(suppl): 5S-13S.
11.Whitehouse I, Beglinger C, Ruttimann G, et al. Inhibition of pentagastrin-stimulated acid secretion after subcutaneous administration of a new somatostatin analogue. Gut 1986, 27:141-146.
12. Soudah HC, Hasler WL, Owyang C. Effect of octreotide on intestinal motility and bacterial overgrowth in scleroderma. N Engl J Med 1991; 325:1461-1467.
13. Williams G, Fuessl H, Kraenzlin M, et al. Postprandial effects of SMS 201-995 on gut hormones and glucose tolerance. Scand J Gastroenterol 1986; 21(suppl 119): 73-83.
14. Lembcke B. Creutzfeldt W, Schleser S, et al. Effect of the somatostatin analogue Sandostatin (SMS 201-995) on gastrointestinal, pancreatic and biliary function and hormone release in normal men. Digestion 1987; 36: 108-124.
15. Gyr KE, Whitehouse l, Beglinger C, et al. Human pharmacological effects of SMS 201-995 on gastric secretion. Scand J Gastroenterol 1986;21(suppl 119):96-102.
16. Londong W, Angerer M, Kutz K, et al. Diminishing efficacy of octreotide (SMS 201-995) on gastric functions of healthy subjects during one-week administration. Gastroenterology 1989; 96: 713-722.
17. Kohler E, Beglinger C, Dettwiler S, et al. Effect of a new somatostatin analogue on pancreatic function in healthy volunteers. Pancreas 1986; 1:154-159.
18. Creutzfeldt W, Lembcke B. Folsch UR, et al. Effect of somatostatin analogue (SMS 201-995, Sandostatin) on pancreatic secretion in humans. Am J Med 1987: 82(suppl 5B): 49-54.
19. Farthing MJG. Octreotide in the treatment of refractory diarrhoea and intestinal fistulae. Gut 1994,3: S5-S10.
20. Moller N, Petrany G, Cassidy D, et al. Effects of the somatostatin analogue SMS 201-995 (Sandostatin) on mouth-to-caecum transit time and absorption of fat and carbohydrates in normal man. Clin Sci 1988; 75:345-350.
21. Fuessl HS, Carolan G, Williams G, et al. Effect of a long-acting somatostatin analogue (SMS 201-995) on postprandial gastric emptying of 99mTc-tin colloid and mouth-to-caecum transit time in man. Digestion 1987; 36: 101-107.
22. Moller N, Petrany G, Cassidy D et al. Effects of the somatostatin analogue SMS 201-995 (Sandostatin) on mouth-to-caecum transit time and absorption of fat and carbohydrates in normal man. Clin Sci 1988; 75: 345-350.
23. Van Liessum PA, Hopman WPM, Pieters GFFM et al. Postprandial gallbladder motility during long-term treatment with the long-acting somatostatin analog SMS 201-995 in acromegaly. J Clin Endocrinol Metab 1989;69:557-562.
24. Anderson JV, Catnach SM, Fairclough PD, Besser GM. Gallstones and long-term treatment with octreotide. Gut 1991; 32: A1228.
25. Eriksson LS, Wahren J. Intravenous and subcutaneous administration of a long-acting somatostatin analogue: Effects on glucose metabolism and splanchnic haemodynamics in healthy subjects. Eur J Clin Invest 1989; 19:213-219.
26. Cooper AM, Braatvedt GD, Qamar Mi et al. Fasting and post-prandial splanchnic blood flow is reduced by a somatostatin analogue (octreotide) in man. Clin Sci 1991; 81: 169-175.
27. Jenkins SA, Bartner JN, Corgett WA, Shields R. Effects of a somatostatin analogue SMS 201- 995 on hepatic haemodynamics in the pig and on intravariceal pressure in man. Br J Surg 1985; 72:1009-1012.
28. Pederzoli P, Bassi C, Falconi M, Albrigo R. Vantini, Micciolo R. Conservative treatment of external pancreatic fistulas with parenteral nutrition alone or in combination with continuous i.v. infusion of somatostatin, glucagon or calcitonin. Surg Gynecol Obstet 1986; 163: 428-432.
29. Bassi C, Falconi M, Caldiron E, Bonora A, Salvia R, Pederzoli P. Somatostatin analogues and pancreatic fistulas. Digestion 1996; 57(suppl 1):94-96.
30. Prinz RA. Pickleman J, Hoffman HD. Treatment of pancreatic cutaneous fistulas with somatostatin analogues. Am J Surg 1987; 155:36-42.
31. Buchler M, Friess H, Klempa I et al. Role of octreotide in the prevention of postoperative complications following pancreatic resection. Am J Surg 1992; 163: 125-131.
32. Friess H, Beger HG, Sulkowsky U et al. Randomized controlled multicentre study of the prevention of complications by octreotide in patients undergoing surgery for chronic pancreatitis. Br J Surg 1995;82:1270-1273.
33. Nubiola P, Badia JM. Martinez-Rodenas F. Gil MJ, Segura M. Sancho J, Sitges-Serra A. Treatment of 27 postoperative enterocutaneous fistulas with the long-life somatostatin analogue SMS 201-995. Ann Surg 1989; 210: 56-58.
34. Borison DI, Bloom AD, Pritchard TJ. Treatment of enterocutaneous and colocutaneous fistulas with early surgery or somatostatin analog. Dis Colon Rec 1992; 35: 635-639.
35. Burroughs AK, McCormick PA, Hughes MD, Sprengers D, DHeygere R, McIntyre N. Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding: Emergency control and prevention of early variceal bleeding. Gastroenterology 1990; 99: 1388-1395.
36. Avgerinos A, Klonis C, Rekoumis G, Gouma P, Papadimitriou N, Raptis S. A prospective randomized trial comparing somatostatin, balloon tamponade and the combination of both methods in the management of acute variceal hemorrhage. J Hepatol 1991; 13: 78-83.
37. McKee R. A study of octreotide in oesophageal varices. Digestion 1990; 45(suppl 1):60-65.
38. Sung JUY, Chung SCS, Lai CW, Chan FKL, Leung JWC, Yung MY, Kassianides C, Li AKC. Octreotide infusion or emergency sclerotherapy for variceal haemorrhage. Lancet 1993; 342:637-641.
39. ODoriso TM. Sandostatin in the treatment of GEP endocrine tumors. Berlin, Springer, 1989.
40. Bajetta E, Carnaghi C, Ferrari L, Spagnoli l, Mazzaferro V, Buzzoni R. The role of somatostatin analogues in the treatment of gastro-enteropancreatic endocrine tumours. Digestion 1996; 57(suppl 1): 72-76.
41. Choi TK, Mok F, Zhan WH, Fan ST, Lai ECS, Wong J. Somatostatin in the treatment of acute pancreatitis: A prospective randomized controlled trial. Gut 1989; 30: 223-227.
42. DAmico D, Favia G, Biasiato R et al. The use of somatostatin in acute pancreatitis - Results of a multicenter trial. Hepatogastroenterology 1990; 37:92-98.
43. Gjorup I, Roikjaer O, Anderson Bet al. A double-blind multicentric trial of somatostatin in the treatment of acute pancreatitis. Surg Gynecol Obstet 1992;175:397-400.
44. Carballo F, Dominguez E, Fernandez-Calvet L, Martinez-Pancorbo C, Garcia A, De la Morena J. Is somatostatin useful in the treatment of acute pancreatitis ? - A meta-analysis. Digestion 1991;49:12-13.
45. Barkin JS, Reiner DK, Deutch E. Sandostatin for control of catheter drainage of pancreatic pseudocyst. Pancreas 1991; 6:245-248.
46. Morali GA, Braverman DZ, Shemesh Det al. Successful treatment of pancreatic pseudocyst with a somatostatin analogue and catheter drainage. Am J Gastroenterol 1991; 86: 515-518.
47. Ellison EC, Garner WL, Mekhjian HS et al. Successful treatment of pancreatic ascites with somatostatin analog (abstract). Gastroenterology 1986; 90:1405.
48. Oktedalen O, Nygaard K, Osnes M. Somatostatin in the treatment of pancreatic ascites. Gastroenterology 1990; 99: 1520-1521.
49. Barrit AS. Treating a patient with pancreatic ascites by an IV infusion of a somatostatin analog. Gastroenterology 1991; 100:1784-1785.
50. Weckbecker G, Raulf F, Tolscvai L, Bruns C. Potentiation of the anti-proliferative effects of anti-cancer drugs by octreotide in vitro and in vivo. Digestion 1996; 57(suppl 1) : 22-28.
51. Tulassay Z, Gupta R, Papp J, Bodnar A. Somatostatin versus cimetidine in the treatment of actively bleeding duodenal ulcer : prospective, randomized. controlled trial. Am J Gastroenterol 1989; 84:6-9.
52. Coraggio F, Bertini G, Catalano A, Scarpato P, Gualdieri L. Clinical, controlled trial of somatostatin with ranitidine and placebo in the control of peptic hemorrhage of the upper gastrointestinal tract. Digestion 1989; 43: 190-195.
53. Tulassay Z, Bodnar A, Farkas l, Papp J, Gupta R. Somatostatin versus secretin in the treatment of actively bleeding gastric erosions. Digestion 1992: 51: 211-216.
2. Praydayrol L, Jomvall H, Mutt V, Ribet A. N-terminally extended somatostatin : The primary structure of somatostatin-28. FEBS Lett 1980;109:55-58.
3. Francis BH, Baskin DG, Saunders DR, et al. Distribution of somatostatin-14 and somatostatin-28 gastrointestinal-pancreatic cells of rats and humans. Gastroenterology 1990;99:1283-1291.
4. Hildebrand P, Ensinck JW, Gyr K, et al. Is somatostatin-28 a physiologic regulator of gastric acid production in man ? Gastroenterology 1994; 103:240-247.
5. Luft R, Efendic S, Hokfelt T. Somatostatin both hormone and neurotransmitter? Diabetologia 1978; 14: 1-13.
6. McNeillis EL, Bausher LP. Stimulatory and inhibitory cyclin AMP responses in rabbit ciliary processes after cervical ganglionectomy. Curr Eye Res 1991; 10: 399-407.
7. Kraicer J, Spence JW. Release of growth hormone from purified somatotrophs : use of high K+ and the ionophore A23187 to elucidate interrelations among Cat+ adenosine 3,5 monophosphate and somatostatin. Endocrinology 1981; 108:651-657.
8. Bauer W, Briner U, Doepfner W, et al. Octreotide : a very potent and selective octapeptide analogue of somatostatin with prolonged action. Life Sci 1982;31:1133-1140
9.Meier RF, Gyr KE. Somatostatin : characterization and the role of analogues. Dig Surg 1994; 11:433-437.
10. Lucey MR, Yamada T. Biochemistry and physiology of gastrointestinal somatostatin. Dig Dis Sci 1989; 34(suppl): 5S-13S.
11.Whitehouse I, Beglinger C, Ruttimann G, et al. Inhibition of pentagastrin-stimulated acid secretion after subcutaneous administration of a new somatostatin analogue. Gut 1986, 27:141-146.
12. Soudah HC, Hasler WL, Owyang C. Effect of octreotide on intestinal motility and bacterial overgrowth in scleroderma. N Engl J Med 1991; 325:1461-1467.
13. Williams G, Fuessl H, Kraenzlin M, et al. Postprandial effects of SMS 201-995 on gut hormones and glucose tolerance. Scand J Gastroenterol 1986; 21(suppl 119): 73-83.
14. Lembcke B. Creutzfeldt W, Schleser S, et al. Effect of the somatostatin analogue Sandostatin (SMS 201-995) on gastrointestinal, pancreatic and biliary function and hormone release in normal men. Digestion 1987; 36: 108-124.
15. Gyr KE, Whitehouse l, Beglinger C, et al. Human pharmacological effects of SMS 201-995 on gastric secretion. Scand J Gastroenterol 1986;21(suppl 119):96-102.
16. Londong W, Angerer M, Kutz K, et al. Diminishing efficacy of octreotide (SMS 201-995) on gastric functions of healthy subjects during one-week administration. Gastroenterology 1989; 96: 713-722.
17. Kohler E, Beglinger C, Dettwiler S, et al. Effect of a new somatostatin analogue on pancreatic function in healthy volunteers. Pancreas 1986; 1:154-159.
18. Creutzfeldt W, Lembcke B. Folsch UR, et al. Effect of somatostatin analogue (SMS 201-995, Sandostatin) on pancreatic secretion in humans. Am J Med 1987: 82(suppl 5B): 49-54.
19. Farthing MJG. Octreotide in the treatment of refractory diarrhoea and intestinal fistulae. Gut 1994,3: S5-S10.
20. Moller N, Petrany G, Cassidy D, et al. Effects of the somatostatin analogue SMS 201-995 (Sandostatin) on mouth-to-caecum transit time and absorption of fat and carbohydrates in normal man. Clin Sci 1988; 75:345-350.
21. Fuessl HS, Carolan G, Williams G, et al. Effect of a long-acting somatostatin analogue (SMS 201-995) on postprandial gastric emptying of 99mTc-tin colloid and mouth-to-caecum transit time in man. Digestion 1987; 36: 101-107.
22. Moller N, Petrany G, Cassidy D et al. Effects of the somatostatin analogue SMS 201-995 (Sandostatin) on mouth-to-caecum transit time and absorption of fat and carbohydrates in normal man. Clin Sci 1988; 75: 345-350.
23. Van Liessum PA, Hopman WPM, Pieters GFFM et al. Postprandial gallbladder motility during long-term treatment with the long-acting somatostatin analog SMS 201-995 in acromegaly. J Clin Endocrinol Metab 1989;69:557-562.
24. Anderson JV, Catnach SM, Fairclough PD, Besser GM. Gallstones and long-term treatment with octreotide. Gut 1991; 32: A1228.
25. Eriksson LS, Wahren J. Intravenous and subcutaneous administration of a long-acting somatostatin analogue: Effects on glucose metabolism and splanchnic haemodynamics in healthy subjects. Eur J Clin Invest 1989; 19:213-219.
26. Cooper AM, Braatvedt GD, Qamar Mi et al. Fasting and post-prandial splanchnic blood flow is reduced by a somatostatin analogue (octreotide) in man. Clin Sci 1991; 81: 169-175.
27. Jenkins SA, Bartner JN, Corgett WA, Shields R. Effects of a somatostatin analogue SMS 201- 995 on hepatic haemodynamics in the pig and on intravariceal pressure in man. Br J Surg 1985; 72:1009-1012.
28. Pederzoli P, Bassi C, Falconi M, Albrigo R. Vantini, Micciolo R. Conservative treatment of external pancreatic fistulas with parenteral nutrition alone or in combination with continuous i.v. infusion of somatostatin, glucagon or calcitonin. Surg Gynecol Obstet 1986; 163: 428-432.
29. Bassi C, Falconi M, Caldiron E, Bonora A, Salvia R, Pederzoli P. Somatostatin analogues and pancreatic fistulas. Digestion 1996; 57(suppl 1):94-96.
30. Prinz RA. Pickleman J, Hoffman HD. Treatment of pancreatic cutaneous fistulas with somatostatin analogues. Am J Surg 1987; 155:36-42.
31. Buchler M, Friess H, Klempa I et al. Role of octreotide in the prevention of postoperative complications following pancreatic resection. Am J Surg 1992; 163: 125-131.
32. Friess H, Beger HG, Sulkowsky U et al. Randomized controlled multicentre study of the prevention of complications by octreotide in patients undergoing surgery for chronic pancreatitis. Br J Surg 1995;82:1270-1273.
33. Nubiola P, Badia JM. Martinez-Rodenas F. Gil MJ, Segura M. Sancho J, Sitges-Serra A. Treatment of 27 postoperative enterocutaneous fistulas with the long-life somatostatin analogue SMS 201-995. Ann Surg 1989; 210: 56-58.
34. Borison DI, Bloom AD, Pritchard TJ. Treatment of enterocutaneous and colocutaneous fistulas with early surgery or somatostatin analog. Dis Colon Rec 1992; 35: 635-639.
35. Burroughs AK, McCormick PA, Hughes MD, Sprengers D, DHeygere R, McIntyre N. Randomized, double-blind, placebo-controlled trial of somatostatin for variceal bleeding: Emergency control and prevention of early variceal bleeding. Gastroenterology 1990; 99: 1388-1395.
36. Avgerinos A, Klonis C, Rekoumis G, Gouma P, Papadimitriou N, Raptis S. A prospective randomized trial comparing somatostatin, balloon tamponade and the combination of both methods in the management of acute variceal hemorrhage. J Hepatol 1991; 13: 78-83.
37. McKee R. A study of octreotide in oesophageal varices. Digestion 1990; 45(suppl 1):60-65.
38. Sung JUY, Chung SCS, Lai CW, Chan FKL, Leung JWC, Yung MY, Kassianides C, Li AKC. Octreotide infusion or emergency sclerotherapy for variceal haemorrhage. Lancet 1993; 342:637-641.
39. ODoriso TM. Sandostatin in the treatment of GEP endocrine tumors. Berlin, Springer, 1989.
40. Bajetta E, Carnaghi C, Ferrari L, Spagnoli l, Mazzaferro V, Buzzoni R. The role of somatostatin analogues in the treatment of gastro-enteropancreatic endocrine tumours. Digestion 1996; 57(suppl 1): 72-76.
41. Choi TK, Mok F, Zhan WH, Fan ST, Lai ECS, Wong J. Somatostatin in the treatment of acute pancreatitis: A prospective randomized controlled trial. Gut 1989; 30: 223-227.
42. DAmico D, Favia G, Biasiato R et al. The use of somatostatin in acute pancreatitis - Results of a multicenter trial. Hepatogastroenterology 1990; 37:92-98.
43. Gjorup I, Roikjaer O, Anderson Bet al. A double-blind multicentric trial of somatostatin in the treatment of acute pancreatitis. Surg Gynecol Obstet 1992;175:397-400.
44. Carballo F, Dominguez E, Fernandez-Calvet L, Martinez-Pancorbo C, Garcia A, De la Morena J. Is somatostatin useful in the treatment of acute pancreatitis ? - A meta-analysis. Digestion 1991;49:12-13.
45. Barkin JS, Reiner DK, Deutch E. Sandostatin for control of catheter drainage of pancreatic pseudocyst. Pancreas 1991; 6:245-248.
46. Morali GA, Braverman DZ, Shemesh Det al. Successful treatment of pancreatic pseudocyst with a somatostatin analogue and catheter drainage. Am J Gastroenterol 1991; 86: 515-518.
47. Ellison EC, Garner WL, Mekhjian HS et al. Successful treatment of pancreatic ascites with somatostatin analog (abstract). Gastroenterology 1986; 90:1405.
48. Oktedalen O, Nygaard K, Osnes M. Somatostatin in the treatment of pancreatic ascites. Gastroenterology 1990; 99: 1520-1521.
49. Barrit AS. Treating a patient with pancreatic ascites by an IV infusion of a somatostatin analog. Gastroenterology 1991; 100:1784-1785.
50. Weckbecker G, Raulf F, Tolscvai L, Bruns C. Potentiation of the anti-proliferative effects of anti-cancer drugs by octreotide in vitro and in vivo. Digestion 1996; 57(suppl 1) : 22-28.
51. Tulassay Z, Gupta R, Papp J, Bodnar A. Somatostatin versus cimetidine in the treatment of actively bleeding duodenal ulcer : prospective, randomized. controlled trial. Am J Gastroenterol 1989; 84:6-9.
52. Coraggio F, Bertini G, Catalano A, Scarpato P, Gualdieri L. Clinical, controlled trial of somatostatin with ranitidine and placebo in the control of peptic hemorrhage of the upper gastrointestinal tract. Digestion 1989; 43: 190-195.
53. Tulassay Z, Bodnar A, Farkas l, Papp J, Gupta R. Somatostatin versus secretin in the treatment of actively bleeding gastric erosions. Digestion 1992: 51: 211-216.
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1996-09-30
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Lohsiriwat D, Watanapa P. The Role of Somatostatin and Somatostatin Analogue in Surgical Practice. Thai J Surg [Internet]. 1996 Sep. 30 [cited 2024 Jul. 18];17(3):134-4. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/250129
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Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.
