Cytomegalovirus Related Gastrointestinal Tract Manifestation of Surgical Significance: Three Cases Presentation and Review

Authors

  • Siriroj Chanthachaiwat Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Vibul Jotiskulratana Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Pornthep Pramyothin Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Vatana Supromajaktr Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Chingyiam Panjapiyakul Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Jatturong Bhupornwiwat Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Wanchai Danvajira Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Thongdee Shaipanich Department of Surgery, Samitivej Hospital, Bangkok, Thailand
  • Chinda Suwanraks Department of Surgery, Samitivej Hospital, Bangkok, Thailand

Abstract

                This article presents three surgical cases with cytomegalovirus (CMV) infection of gastrointestinal tract in recent years (1994-1995) at Samitivej Hospital. The first patient had perforation of CMV infected duodenum with defect in cellular mediated immune response. The second patient was a six-week post renal transplanted recipient who developed CMV colitis and renal allograft infection. The third patient, with normal immune response, had massive gastrointestinal hemorrhage from CMV jejunitis. Surgical resection had to be done to control the bleeding. Only the third patient had satisfactory response to antiviral therapy.

                With rising incidence of immune suppressed patients, complicated CMV infection would be more often encountered, especially in this particular group of patients. Preventive measures have been invariably used to reduce rate of CMV infection among organs transplanted patients. High index of suspicion should be the mainstay of early detection and management in the immunosuppressed patients, especially those who harbour HIV.  However, patients with normal immune response but have atypical clinical presentation of CMV infection should be cautiously search for.

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Published

1995-06-30

How to Cite

1.
Chanthachaiwat S, Jotiskulratana V, Pramyothin P, Supromajaktr V, Panjapiyakul C, Bhupornwiwat J, Danvajira W, Shaipanich T, Suwanraks C. Cytomegalovirus Related Gastrointestinal Tract Manifestation of Surgical Significance: Three Cases Presentation and Review. Thai J Surg [Internet]. 1995 Jun. 30 [cited 2024 Nov. 23];16(1):26-32. Available from: https://he02.tci-thaijo.org/index.php/ThaiJSurg/article/view/250196

Issue

Vol. 16 No. 1 (1995): January - June

Section

Review Articles

License

Articles must be contributed solely to The Thai Journal of Surgery and when published become the property of the Royal College of Surgeons of Thailand. The Royal College of Surgeons of Thailand reserves copyright on all published materials and such materials may not be reproduced in any form without the written permission.