Ultrasound-Guided Core Needle Biopsy versus Fine-Needle Aspiration Biopsy for Thyroid Nodules
Keywords:
Core needle biopsy, Fine needle aspiration biopsy, Thyroid noduleAbstract
Objective: The use of core needle biopsy (CNB) may help overcome limitations of fine needle aspiration biopsy (FNAB) for thyroid nodules. The aim of the present study was to compare ultrasound-guided (US-G) CNB with US-G FNAB in terms of diagnostic adequacy based on the 2017 Bethesda System for Reporting Thyroid Cytopathology (the 2017 Bethesda System).
Patients and Methods: A retrospective cohort study of two groups of patients with thyroid nodules who underwent US-G FNAB and CNB at Pakkred Community Hospital between January 1, 2017 to December 31, 2020 was performed. The two groups were compared in terms of diagnostic adequacy.
Results: There were 31 patients in each group. In the CNB group, adequate results in terms of the 2017 Bethesda System were obtained in 77% of patients, while FNAB yielded only 26% adequacy, a statistically significant difference (p < 0.001). Size of the thyroid nodule greater than 2 cm was significantly related to increased adequacy. Cystic or solid or mixed composition of nodules did not significantly impact adequacy.
Conclusion: Ultrasound-guided CNB performed better than FNAB in terms of adequate biopsy results based on the 2017 Bethesda System.
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