Outcomes of Off-Pump Coronary Artery Bypass Grafting in Ischemic Cardiomyopathy
Keywords:
Off-pump coronary artery bypass, Cardiomyopathy, Left ventricle dysfunction, Coronary artery diseaseAbstract
Objective: Surgical coronary revascularization for coronary artery disease (CAD) with reduced left ventricular ejection fraction (LVEF) entails a high risk of postoperative complications and mortality. This study aimed to evaluate the surgical outcomes of off-pump coronary artery bypass grafting (OPCAB) in ischemic cardiomyopathy patients in our hospital.
Patients and Methods: From January 2012 to December 2018, eighty CAD patients with low LVEF ≤ 35% who underwent isolated OPCAB were included in the present study. In-hospital mortality, major adverse cardiovascular and cerebrovascular events were evaluated, and factors associated with mortality were analyzed.
Results: The mean preoperative LVEF was 26%, while their mean EuroSCORE II was 11.9, and their in-hospital mortality rate was 16% (13 patients). Low cardiac output syndrome was found in 3 patients, congestive heart failure in 2 patients, and cardiogenic shock in 3 patients. There were no postoperative strokes or myocardial infarction, and postoperative LVEF was significantly improved, with an average of 38% (P = 0.040). Insulin-dependent type II diabetes mellitus was significantly associated with increased in-hospital mortality (P < 0.001).
Conclusions: Patients with coronary artery disease and ischemic cardiomyopathy showed significantly improved left ventricular ejection fraction after off-pump coronary artery bypass grafting surgery. There were no postoperative myocardial infarction or stroke in the present study. Insulin-dependent type II diabetes mellitus was significantly associated with increased in-hospital mortality.
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