Cutaneous Calcinosis Caused by Parenteral Nutrition Extravasation in a Neonate Treated by Surgical Debulking: Report of a Case
Keywords:
Calcinosis cutis, Parenteral nutrition, SurgeryAbstract
Calcinosis cutis is an abnormal deposition of calcium compounds in the subcutaneous tissue that can result from various causes, including malignancy, metabolic diseases, and iatrogenic. In this report, we described a case of calcinosis cutis occurring in a newborn infant following extravasation of parenteral nutrition in neonatal intensive care. Due to its large size and an impending loss of the overlying skin, surgical removal of the calcinotic mass, followed by a full-thickness skin grafting. Evidence from energy-dispersive X-ray spectroscopy suggested that extravasation of the parenteral nutrition and precipitation of calcium phosphate and calcium carbonate explained the pathophysiology of calcium salt precipitation. This report addresses a potential complication from parenteral nutrition extravasation and suggests early management that might prevent the necessity for a major operation.
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