Diabetic Striatopathy: A Rare Microvascular Neurological Diabetic Complication

  • Kaset Chimplee Department of Internal Medicine, School of Medicine, Mae Fah Luang University
Keywords: Diabetic striatopathy, Choreoathetosis, Hemichorea/hemiballism, Corpus striatum

Abstract

Diabetic striatopathy is a rare neurological diabetic complication which has an incidence of 1:100,000 population. This report presents a female with poorly controlled type 2 diabetes and hypertension, who presented with right sided choreoathetosis. No other neurological abnormalities were found on physical examination. Brain imaging showed hyperdensity of the left caudate and left lentiform nuclei on non-contrast CT scan. The patient made a complete recovery from the abnormal movements following tight glucose control and introduction of trihexyphenidyl and haloperidol. A follow up CT scan 6 months following presentation revealed resolution of the previous striatal abnormalities.

Downloads

Download data is not yet available.

References

Özgür A, Esen K, Kaleağası H, YılmazA, Kara E. Diabetic striatopathy in a patient with hemiballism. Emergency radiology 2015; 22: 347-9.

Chua CB, Sun CK, Hsu CW, Tai YC, Liang CY, Tsai IT. “Diabetic striatopathy”: clinical presentations, controversy, pathogenesis, treatments, and outcomes. Scientific reports 2020; 10: 1-11.

Cosentino C, Torres L, Nuñez Y, Suarez R, Velez M, Flores M. Hemichorea/hemiballism associated with hyperglycemia: report of 20 cases. Tremor and other hyperkinetic movements 2016; 6: 402-5.

Lucassen EB, Delfyett WT, Stahl MC. Persistent hemichorea and caudate atrophy in untreated diabetic striatopathy: A case report. Case reports in neurology 2017; 9: 299-303.

Lupescu IC, Lupescu IG, Arbune A, Toron B, Dulamea AO. A few thoughts on diabetic striatopathy-case report and short review. Romanian Journal of Neurology 2020; 19: 41-5.

Homaida M, Kanodia AK, Young N, Yu WM. Diabetic striatopathy: a rare condition and diagnostic dilemma. BMJ Case Reports 2021;14: DOI:10. 1136/bcr-2020-240141

Abe Y, Yamamoto T, Soeda T, Kumagai T, Tanno Y, Kubo J, et al. (2009). Diabetic striatal disease: clinical presentation, neuroimaging, and pathology. Internal Medicine 2009; 48:1135-41.

Chutpiboonwat P, Chutinet A, Tontiwutikul B, Snabboon T. (2020). Diabetic Striatopathy. Acta Médica Portuguesa 2020; 33:13.

Tocco P, Barbieri F, Bonetti B, Barillari M, Marangi A, Tinazzi M. Hemichorea-hemiballismus in patients with non-ketotic hyperglycemia. Neurol Sci 2016; 37: 297-8.

Published
2021-08-26
How to Cite
Chimplee, K. (2021). Diabetic Striatopathy: A Rare Microvascular Neurological Diabetic Complication. Greater Mekong Sub-Region Medical Journal, 1(3), 151-156. Retrieved from https://he02.tci-thaijo.org/index.php/gmsmj/article/view/251223
Section
Review Articles