Physiologic Changes in The Elderly
Keywords:
Physiology, Change, Elderly, AgingAbstract
As the older population has been tremendously growing, the physiologic changes of all organ systems in increasing age should be extensively recognized. The changes include the increased risk of myocardial infarction or hypertension in cardiovascular system, respiratory failure in respiratory system, malignant melanoma in aging skin. The impaired coordination of muscles of swallowing also increases risk of aspiration. In addition, the immune system with altered function slows down the inflammation process of the body, leading to atypical presentation when the patient is acute illness. In this article, aging changes of organ systems and the potentially altered risk of diseases including the pharmacokinetic and pharmacodynamic changes in the elderly are described for the benefit of patient care.
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