Acute Fever with Painful Swelling of Leg in Alcoholic Cirrhosis Patient

Authors

  • Sarut Lerwiwattaworn School of Medicine, Mae Fah Luang University, Chiang Rai 57100, Thailand

Keywords:

Liver cirrhosis, Aeromonas infection, Sepsis, Septic shock

Abstract

Patients with liver cirrhosis are susceptible to bacterial infection. The common infection sites are spontaneous bacteremia, urinary tract infection, pneumonia, soft tissue infection and spontaneous bacterial peritonitis. Gram-negative bacteria such as Escherichia coli and Klebsiella spp. were the most common microorganisms causing bacteremia in cirrhotic patients. Vibrio, Aeromonas, and Campylobacter spp. occasionally caused bacteremia in cirrhotic patients, but these individuals are at great risks for invasive infections. The vibrios are found in marine and surface waters. Aeromonads are inhabitants of aquatic ecosystems, worldwide, and are found in fresh and brackish waters. The campylobacters are found in many species of animals, including many domesticated animals. Here we report a case of soft tissue infection from Aeromonas hydrophila in liver cirrhosis patient which caused rapidly progressive septicemia and shock.

References

Smith J, Fratamico PM, Uhlich G. Molecular mechanisms involved in biofilm formation by food-associated bacteria in Biofilms in the Food and Beverage Industries. A volume in Woodhead Publishing Series in Food Science, Technology and Nutrition. Fratamico PM, Annous BA and Nereus W. Gunther NW, IV. Eds. Woodhead Publishing. 2009, pp 42-98. https://doi.org/10.1533/9781845697167.1.42

O'Beirne D, Francis GA. Reducing pathogen risks in MAP-prepared produce in Novel Food Packaging Techniques. Woodhead Publishing Series in Food Science, Technology and Nutrition. Ahvenainen R, ed. Woodhead Publishing. 2003, pp 231-75. https://doi.org/10.1533/9781855737020.2.231

Fernández-Bravo A, Figueras MJ. An Update on the Genus Aeromonas: Taxonomy, Epidemiology, and Pathogenicity. Microorganisms. 2020; 8 (1):129. https://doi.org/10.3390/microorganisms8010129

Albillos A, Lario M, Álvarez-Mon M. Cirrhosis-associated immune dysfunction: Distinctive features and clinical relevance. Journal of Hepatology. 2014; 61: 1385-96. https://doi.org/10.1016/j.jhep.2014.08.010

Jenne CN, Kubes P. Immune surveillance by the liver. Nat Immunol. 2013; 14: 996-1006. https://doi.org/10.1038/ni.2691

Helmy KY, Katschke Jr KJ, Gorgani NN, Kljavin NM, Elliott JM, Diehl L, et al. CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogens. Cell. 2006; 124: 915-27. https://doi.org/10.1016/j.cell.2005.12.039

Rimola A, Soto R, Bory F, Arroyo V, Piera C, Rodes J. Reticuloendothelial system phagocytic activity in cirrhosis and its relation to bacterial infections and prognosis. Hepatology. 1984; 4: 53-8. https://doi.org/10.1002/hep.1840040109

Arvaniti V, D'Amico G, Fede G, Manousou P, Tsochatzis E, Pleguezuelo M, et al. Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis. Gastroenterology. 2010; 139: 1246-56. https://doi.org/10.1053/j.gastro.2010.06.019

Moreau R, Jalan R, Gines P, Pavesi M, Angeli P, Cordoba J, et alCANONIC Study Investigators of the EASL-CLIF Consortium. Acute-on-chronic liver failure is a distinct syndrome that develops in patients with acute decompensation of cirrhosis. Gastroenterology. 2013; 144: 1426-37. https://doi.org/10.1053/j.gastro.2013.02.042

Downloads

Published

2024-12-27

How to Cite

Lerwiwattaworn, S. (2024). Acute Fever with Painful Swelling of Leg in Alcoholic Cirrhosis Patient. Greater Mekong Subregion Medical Journal, 5(1), 32–34. Retrieved from https://he02.tci-thaijo.org/index.php/gmsmj/article/view/272068

Issue

Section

Case Report