Symptomatic Dry Eye Prevalence and Related Factors in an Open University, Bangkok, Thailand

Authors

  • Patarakorn Tawonkasiwattanakun Master of Public Health Program, Faculty of Public Health, Mahidol University
  • Varakorn Kosaisavee Faculty of Public Health, Mahidol university, Thailand
  • Nawarat Suwannapong Faculty of Public Health, Mahidol University, Thailand
  • Mathuros Tipayamongkholgul Mahidol University, Faculty of Public Health, Thailand

Keywords:

productive-age group, symptomatic dry eye, prevalence, related factors, open university Thailand

Abstract

Although dry eye is not a life-threatening disease, its chronic conditions cause ocular damage,  and impair daily activities and work performance. Dry eye is a geriatric disease; however, its prevalence has recently increased among the productive-age group. In Thailand, open universities offering distance learning necessitate excessive eye use among members that possibly induces dry eye. This study aimed to explore the prevalence of symptomatic dry eye and its associated factors in an open university’s productive-age group in Bangkok by using an internet-based cross-sectional study. Six-hundred and thirty university members were conveniently selected from 13 academic faculties. Four sections of the structured questionnaire i.e. 1.) personal factors, 2.) Thai-Perceived Stress Scale-10 and the Thai version of the Pittsburgh sleep quality index, 3.) digital gadget use, and 4.) McMonies questionnaire were transformed to online versions and sent to selected subjects from May to June 2020. Of 542 respondents, the overall prevalence of symptomatic dry eye was 17.5%. The prevalence among those aged <30 years was 10%, and 40% among those aged >49 years. Multiple binary logistic regression revealed a significant association between age >49 years (OR=9.01), wearing contact lenses (OR=2.00), and poor sleep quality (OR=1.70) and higher prevalence of dry eye (p<0.05). The high prevalence of symptomatic dry eye in this study emphasized the need for public health attention on dry eye prevention among the productive-age group in academic institutions. Productive-age individuals who are aged >49 years, wear contact lenses and have poor sleep quality should be advised to be aware of dry eye condition.

References

World Health Organization. World report on vision [updated: 2019 Oct 08] Available from: https://www.who.int/publications/i/item/world-report-on-vision, accessed May 8, 2021.

Craig JP, Nichols KK, Akpek EK, Caffery B, Dua HS, Joo CK, et al. TFOS DEWS II definition and classification report. Ocul Surf 2017; 15(3): 276-83.

van Tilborg MM, Murphy PJ, Evans KS. Impact of dry eye symptoms and daily activities in a modern office. Optom Vis Sci 2017; 94(6): 688-93.

Nichols KK, Bacharach J, Holland E, Kislan T, Shettle L, Lunacsek O, et al. Impact of dry eye disease on work productivity, and patients' satisfaction with over-the-counter dry eye treatments. Invest Ophthalmol Vis Sci 2016; 57(7): 2975-82.

Binyousef FH, Alruwaili SA, Altammami AF, Alharbi AA, Alrakaf FA, Almazrou AA. Impact of dry eye disease on work productivity among Saudi workers in Saudi Arabia. Clin Ophthalmol 2021; 15: 2675-81.

Clegg JP, Guest JF, Lehman A, Smith AF. The annual cost of dry eye syndrome in France, Germany, Italy, Spain, Sweden and the United Kingdom among patients managed by ophthalmologists. Ophthalmic Epidemiol 2006; 13(4): 263-74.

Waduthantri S, Yong SS, Tan CH, Shen L, Lee MX, Nagarajan S, et al. Cost of dry eye treatment in an Asian clinic setting. PLoS One 2012; 7(6): e37711.

Farrand KF, Fridman M, Stillman IO, Schaumberg DA. Prevalence of diagnosed dry eye disease in the United States among adults aged 18 years and older. Am J Ophthalmol 2017; 182: 90-8.

Vehof J, Snieder H, Jansonius N, Hammond CJ. Prevalence and risk factors of dry eye in 79,866 participants of the population-based lifelines cohort study in the Netherlands. Ocul Surf 2021; 19: 83-93.

Yu X, Guo H, Liu X, Wang G, Min Y, Chen SS, et al. Dry eye and sleep quality: a large community-based study in Hangzhou. Sleep 2019; 42(11): zsz160.

Um SB, Kim NH, Lee HK, Song JS, Kim HC. Spatial epidemiology of dry eye disease: findings from South Korea. Int J Health Geogr 2014; 13: 31.

Tan LL, Morgan P, Cai ZQ, Straughan RA. Prevalence of and risk factors for symptomatic dry eye disease in Singapore. Clin Exp Optom 2015; 98(1): 45-53.

Lekhanont K, Rojanaporn D, Chuck RS, Vongthongsri A. Prevalence of dry eye in Bangkok, Thailand. Cornea. 2006; 25(10): 1162-7.

Kasetsuwan N GS, Erjongmanee S, Thienprasiddhi P, Jitapunkul S. Prevalence of dry eyes in elderly Thai population (the Romklao eye study). Asian Biomed (Res Rev News) 2012; 6: 875-2.

Dana R, Bradley JL, Guerin A, Pivneva I, Stillman IO, Evans AM, et al. Estimated prevalence and incidence of dry eye disease based on coding analysis of a large, all-age United States Health Care System. Am J Ophthalmol 2019; 202: 47-54.

Garza-Leon M, Valencia-Garza M, Martinez-Leal B, Villarreal-Pena P, Marcos-Abdala HG, Cortez-Guajardo AL, et al. Prevalence of ocular surface disease symptoms and risk factors in group of university students in Monterrey, Mexico. J Ophthalmic Inflamm Infect 2016; 6(1): 44.

Asiedu K, Kyei S, Boampong F, Ocansey S. Symptomatic dry eye and its associated factors: a study of university undergraduate students in Ghana. Eye Contact Lens 2017; 43(4): 262-6.

Shanti Y, Shehada R, Bakkar MM, Qaddumi J. Prevalence and associated risk factors of dry eye disease in 16 northern West bank towns in Palestine: a cross-sectional study. BMC Ophthalmol 2020; 20(1): 26.

Hashemi H, Khabazkhoob M, Kheirkhah A, Emamian MH, Mehravaran S, Shariati M, et al. Prevalence of dry eye syndrome in an adult population. Clin Exp Ophthalmol 2014; 42(3): 242-8.

Ahn JM, Lee SH, Rim TH, Park RJ, Yang HS, Kim TI, et al. Prevalence of and risk factors associated with dry eye: the Korea National Health and Nutrition Examination Survey 2010-2011. Am J Ophthalmol 2014; 158(6): 1205-14 e7.

Magno MS, Utheim TP, Snieder H, Hammond CJ, Vehof J. The relationship between dry eye and sleep quality. Ocul Surf 2021; 20: 13-9.

Alshamrani AA, Almousa AS, Almulhim AA, Alafaleq AA, Alosaimi MB, Alqahtani AM, et al. Prevalence and risk factors of dry eye symptoms in a Saudi Arabian population. Middle East Afr J Ophthalmol 2017; 24(2): 67-73.

Koksoy Vayisoglu S, Oncu E, Dursun O, Dinc E. Investigation of dry eye symptoms in lecturers by Ocular Surface Disease Index. Turk J Ophthalmol 2019; 49(3): 142-8.

Shehadeh-Mashor R, Mimouni M, Shapira Y, Sela T, Munzer G, Kaiserman I. Risk factors for dry eye after refractive surgery. Cornea 2019; 38(12): 1495-9.

Cetinkaya S, Mestan E, Acir NO, Cetinkaya YF, Dadaci Z, Yener HI. The course of dry eye after phacoemulsification surgery. BMC Ophthalmol 2015; 15: 68.

Uchino M, Nishiwaki Y, Michikawa T, Shirakawa K, Kuwahara E, Yamada M, et al. Prevalence and risk factors of dry eye disease in Japan: Koumi study. Ophthalmology 2011; 118(12): 2361-7.

Hyon JY, Yang HK, Han SB. Association between dry eye disease and psychological stress among paramedical workers in Korea. Sci Rep 2019; 9(1): 3783.

Hu JW, Zhu XP, Pan SY, Yang H, Xiao XH. Prevalence and risk factors of dry eye disease in young and middle-aged office employee: a Xi'an Study. Int J Ophthalmol 2021; 14(4): 567-73.

Uchino M, Yokoi N, Uchino Y, Dogru M, Kawashima M, Komuro A, et al. Prevalence of dry eye disease and its risk factors in visual display terminal users: the Osaka study. Am J Ophthalmol 2013; 156(4): 759-66.

Li S, He J, Chen Q, Zhu J, Zou H, Xu X. Ocular surface health in Shanghai University students: a cross-sectional study. BMC Ophthalmol 2018; 18(1): 245.

Electronic Transactions Development Agency. Thailand Internet User Profile 2018 [updated: 2019 Feb] Available from: https://www.etda.or.th/th/Useful-Resource/publications/Thailand-Internet-User-Profile-2018_EN.aspx, accessed May 8, 2021.

Siritarungsri B, Suwansumrit S. Evaluation of the use of webcasting to support nursing learning. Journal of Nursing Science and Health 2012(3): 36-42.

Lertwisuttipaiboon S, Pumpaibool T, Neeser KJ, Kasetsuwan N. Associations of preventive strategies with symptoms of eye strain among Sukhothai Thammathirat Open University staff in Thailand. J Health Res 2016; 30(1): 33-8.

Matha W, Madarsha KB, editors. Mobile learning acceptance among students of Ramkhamhaeng University, Thailand. The 1st YRU International Conference in Islamic Education 2013 Jan 23 – 26; 2013 2013 Jan 23 – 26; Songkla, Thailand: Yala Rajabhat University Press.

Deutskens E, Ruyter Kd, Wetzels M, Oosterveld P. Response rate and response quality of internet-based surveys: an experimental study. Marketing letters 2004; 15(1): 21-36.

Sitasuwan T, Bussaratid S, Ruttanaumpawan P, Chotinaiwattarakul W. Reliability and validity of the Thai version of the Pittsburgh Sleep Quality Index. J Med Assoc Thai 2014; 97 Suppl 3:S57-67.

Wongpakaran N, Wongpakaran T. The Thai version of the PSS-10: An Investigation of its psychometric properties. Biopsychosoc Med 2010; 4: 6.

McMonnies CW, Ho A. Patient history in screening for dry eye conditions. J Am Optom Assoc 1987; 58(4): 296-301.

Hyon JY, Yang HK, Han SB. Dry eye symptoms may have association with psychological stress in medical students. Eye Contact Lens 2019; 45(5): 310-4.

Rossi GCM, Scudeller L, Bettio F, Pasinetti GM, Bianchi PE. Prevalence of dry eye in video display terminal users: a cross-sectional Caucasian study in Italy. Int Ophthalmol 2019; 39(6): 1315-22.

Sullivan BD, Evans JE, Dana MR, Sullivan DA. Influence of aging on the polar and neutral lipid profiles in human meibomian gland secretions. Arch Ophthalmol 2006; 124(9): 1286-92.

Bakkar MM, Shihadeh WA, Haddad MF, Khader YS. Epidemiology of symptoms of dry eye disease (DED) in Jordan: A cross-sectional non-clinical population-based study. Cont Lens Anterior Eye 2016; 39(3): 197-202.

Kojima T. Contact lens-Associated dry eye disease: recent advances worldwide and in Japan. Invest Ophthalmol Vis Sci 2018; 59(14): DES102-DES8.

Au NH, Mather R, To A, Malvankar-Mehta MS. Sleep outcomes associated with dry eye disease: a systematic review and meta-analysis. Can J Ophthalmol 2019; 54(2): 180-9.

Lee YB, Koh JW, Hyon JY, Wee WR, Kim JJ, Shin YJ. Sleep deprivation reduces tear secretion and impairs the tear film. Invest Ophthalmol Vis Sci 2014; 55(6): 3525-31.

Wood B, Rea MS, Plitnick B, Figueiro MG. Light level and duration of exposure determine the impact of self-luminous tablets on melatonin suppression. Appl Ergon 2013; 44(2): 237-40.

Chang AM, Aeschbach D, Duffy JF, Czeisler CA. Evening use of light-emitting eReaders negatively affects sleep, circadian timing, and next-morning alertness. Proc Natl Acad Sci U S A 2015; 112(4): 1232-7.

Downloads

Published

2021-12-30

Issue

Section

Original Articles