Enhanced Efficacy of Dane Fukang Decoction in Comparison to Conventional Treatments for Endometriosis

Authors

  • Preeyanuch Ketprathum Department of Biostatistics, Faculty of Public Health, Mahidol University, Bangkok, Thailand. Email: preeyanuch.ket@student.mahidol.ac.th
  • Hathaikan Chootrakool Department of Biostatistics, Faculty of Public Health, Mahidol University, Thailand. Email: hathaikan.cho@mahidol.ac.th
  • Chuleekorn Sritonchai Department of Obstetrics and Gynecology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand. Email: hathaikan.cho@mahidol.ac.th
  • Pichet Treewai Email: pichet.treewai@gmail.com

Keywords:

Endometriosis, Dane fukang decoction, Gestrinone, Chinese medicine

Abstract

Endometriosis is a chronic gynecological disorder affecting millions of women worldwide, characterized by the growth of endometrial-like tissue outside the uterus. Conventional treatments, including hormonal therapies and surgery, often have limitations and side effects. This review explores the therapeutic potential of Dane Fukang decoction, a traditional Chinese herbal formula, in managing endometriosis. By examining this herbal remedy's pharmacological mechanisms, clinical evidence, and safety profile, we aim to provide a comprehensive understanding of its role in endometriosis treatment.

The review discusses the multi-targeted actions of key herbs in Dane Fukang decoction, such as Radix Astragalus and Radix Angelicae Sinensis, which possess anti-inflammatory, anti-angiogenic, and immunomodulatory properties relevant to the pathophysiology of endometriosis. The clinical efficacy of Dane Fukang decoction in alleviating endometriosis symptoms, as demonstrated by higher total effective rates and fewer adverse reactions compared to conventional medications like gestrinone, is also highlighted.

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Published

2025-04-30

Issue

Vol. 55 No. 1 (2025): Vol. 55 No. 1 (Jan - Apr 2025)

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Review Article

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