Burden of Lower Urinary Tract Symptoms among Nepalese Adults with Type 2 Diabetes Mellitus
Keywords:
Diabetes, Lower urinary Tract symptoms, Burden of disease, NepalAbstract
Background: Lower urinary tract symptoms (LUTS) represents a significant burden in patients with Type 2 Diabetes Mellitus (T2DM). With a wide range of LUTS prevalence, a cross-sectional study aimed to assess the prevalence and burden of LUTS among Nepalese patients with Type 2 Diabetes. Methods: The burden was assessed in terms of quality adjusted life years (QALYs) and QALYs lost. Data were collected from patients with DM who lived in nine districts in Nepal during 2022-2023. Results: Among 480 respondents, more than a half of them were male with mean age of 59.90 ± 12.13 years. The LUTS was more present in Nepalese female (79.9%) than males (75.2%), with no statistical difference between sex (p = 0.27). There was statistically significant difference of Euro Quality of life (EQ-5D) between people who had only DM compared to people with DM and LUTS (p <.001). Using bivariate analysis, there was an association between LUTS and QALYs (p <.001). The QALYs lost was significantly higher in people who had both LUTS and DM. People with DM alone were three times more likely to have perfect health than those with DM and LUTS. Significant positive correlation between age, blood sugar levels, duration of diabetes and LUTS were found; whereas significant negative correlations between health behavior, social support, access to health and LUTS were reported. Conclusion: These findings suggest that diabetic patients should be screened for LUTS. Further, social perceptions and access to care should be managed to reduce the burden of LUTS among older DM patients.
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