Metastasis of cardiac rhabdomyosarcoma at lumbar spine: case report
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Published:
Feb 20, 2016
Keywords:
Metastasis cardiac tumor pleomorphic rhabdomyosarcoma lumbar spine case report
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Abstract
We report a case and review literatures of a 78-year-old man presenting with progressive dyspnea for 1 month. A diagnosis of cardiac pleomorphic rhabdomyosarcoma with lung and scalp metastasis was made then surgical tumor removal was performed. One month later the patient complained of severe low back pain. After complete investigation, he was diagnosed with metastatic rhabdomyosarcoma at lumbar spine and adjacent paravertebral soft-tissue. He underwent a second operation resulting in a satisfactory early postoperative outcome. He passed away approximately 6 weeks later as a result of severe congestive heart failure and irreversible respiratory failure.
This is the first case report of metastatic cardiac pleomorphic rhabdomyosarcoma at lumbar spine which is assumed to be a rare and aggressive disease.
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Case Report
References
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16. Rao G, Suki D, Chakrabarti I, Feiz-Erfan I, Mody MG, McCutcheon IE, et al. Surgical management of primary and metastatic sarcoma of the mobile spine. J Neurosurg Spine. 2008;9:120-8.
17. Merimsky O, Kollender Y, Bokstein F, et al. Radiotherapy for spinal cord compression in patients with soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2004;58:1468-73.
18. Arnold PM, Roh S, Ha TM, Anderson KK. Metastatic synovial sarcoma with cervical spinal cord compression treated with posterior ventral resection: case report. J Spinal Cord Med. 2010;33:80-4.
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20. Kuan-Nien Chou D-YH, Herng-Sheng Lee, and Hsin-I Ma. Cardiac Rhabdomyosarcoma with Metastatic T1 Vertebral Compression Fracture. J Med Sci. 2012;32:191-4.
21. Paul M. Arnold MCP, Kathy Newell, John J. Kepes, J. Brantley Thrasher. Thoracic spinal cord compression secondary to metastatic synovial sarcoma: case report. Coluna/Columna. 2009;8:206-11.
2. Hui KS, Green LK, Schmidt WA. Primary cardiac rhabdomyosarcoma: definition of a rare entity. Am J Cardiovasc Pathol. 1988;2:19-29.
3. Miralles A, Bracamonte L, Soncul H, Diaz del Castillo R, Akhtar R, Bors V, et al. Cardiac tumors: clinical experience and surgical results in 74 patients. Ann Thorac Surg. 1991;52:886-95.
4. Ostrowski S, Marcinkiewicz A, Kosmider A, Jaszewski R. Sarcomas of the heart as a difficult interdisciplinary problem. Archives of medical science : AMS. 2014;10:135-48.
5. Tiyapant A, Tantranont R. Primary cardiac embryonal rhabdomyosarcoma: the first officially case reported of Thailand. J Med Assoc Thai. 1991;74:176-80.
6. Shapeero LG, Couanet D, Vanel D, Ackerman LV, Terrier-Lacombe MJ, Flamant F, et al. Bone metastases as the presenting manifestation of rhabdomyosarcoma in childhood. Skeletal radiology. 1993;22:433-8.
7. Bendel EC, Maleszewski JJ, Araoz PA. Imaging sarcomas of the great vessels and heart. Semin ultrasound CT MR. 2011;32:377-404.
8. Grandmougin D, Fayad G, Decoene C, Pol A, Warembourg H. Total orthotopic heart transplantation for primary cardiac rhabdomyosarcoma: factors influencing long-term survival. Ann Thorac Surg. 2001;71:1438-41.
9. Wolden SL, Anderson JR, Crist WM, Breneman JC, Wharam MD, Jr., Wiener ES, et al. Indications for radiotherapy and chemotherapy after complete resection in rhabdomyosarcoma: A report from the Intergroup Rhabdomyosarcoma Studies I to III. J Clin Oncol. 1999;17:3468-75.
10. Little DJ, Ballo MT, Zagars GK, Pisters PW, Patel SR, El-Naggar AK, et al. Adult rhabdomyosarcoma: outcome following multimodality treatment. Cancer. 2002;95:377-88.
11. Esnaola NF, Rubin BP, Baldini EH, Vasudevan N, Demetri GD, Fletcher CD, et al. Response to chemotherapy and predictors of survival in adult rhabdomyosarcoma. Ann Surg. 2001;234:215-23.
12. Yoshikawa H, Ueda T, Mori S, Araki N, Kuratsu S, Uchida A, et al. Skeletal metastases from soft-tissue sarcomas. Incidence, patterns, and radiological features. J Bone Joint Surg Br. 1997;79:548-52.
13. Vincenzi B, Frezza AM, Schiavon G, Santini D, Dileo P, Silletta M, et al. Bone metastases in soft tissue sarcoma: a survey of natural history, prognostic value and treatment options. Clin Sarcoma Res. 2013;3:6.
14. Oberlin O, Rey A, Lyden E, Bisogno G, Stevens MC, Meyer WH, et al. Prognostic factors in metastatic rhabdomyosarcomas: results of a pooled analysis from United States and European cooperative groups. J Clin Oncol. 2008;26:2384-9.
15. Kaloostian PE, Zadnik PL, Etame AB, Vrionis FD, Gokaslan ZL, Sciubba DM. Surgical management of primary and metastatic spinal tumors. Cancer control : journal of the Moffitt Cancer Center. 2014;21:133-9.
16. Rao G, Suki D, Chakrabarti I, Feiz-Erfan I, Mody MG, McCutcheon IE, et al. Surgical management of primary and metastatic sarcoma of the mobile spine. J Neurosurg Spine. 2008;9:120-8.
17. Merimsky O, Kollender Y, Bokstein F, et al. Radiotherapy for spinal cord compression in patients with soft-tissue sarcoma. Int J Radiat Oncol Biol Phys. 2004;58:1468-73.
18. Arnold PM, Roh S, Ha TM, Anderson KK. Metastatic synovial sarcoma with cervical spinal cord compression treated with posterior ventral resection: case report. J Spinal Cord Med. 2010;33:80-4.
19. Fan HG, Meng J, Pan SW, Zheng Z, Hu SS. Diagnosis, operation, recurrence, metastasis, and death: a case of primary cardiac rhabdomyosarcoma. J Card Surg. 2009;24:480-2.
20. Kuan-Nien Chou D-YH, Herng-Sheng Lee, and Hsin-I Ma. Cardiac Rhabdomyosarcoma with Metastatic T1 Vertebral Compression Fracture. J Med Sci. 2012;32:191-4.
21. Paul M. Arnold MCP, Kathy Newell, John J. Kepes, J. Brantley Thrasher. Thoracic spinal cord compression secondary to metastatic synovial sarcoma: case report. Coluna/Columna. 2009;8:206-11.