Comparison of blood pressure and pulse rate in hypertensive patient following the injection of 4% articaine with epinephrine 1 : 100,000 and 1 : 200,000

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Thachaya Satavuthi
Thitiporn Kangwannarongkul
Nattawut Supachawaroj
Chanaporn Phaengdee
Piyagorn Arunrukthavon
Sujari Jumpawong
Arthitaya Suddee
Nunthachat Sittichamroenkhun
Chawanwaree Srithakaew

Abstract

This research aimed to study the changes in blood pressure and pulse rate after the administration of 4% articaine with 1 : 100,000 and 1 : 200,000 epinephrine in 60 well-controlled hypertensive patients. The data collection included blood pressure, pulse rate, the numeric rating scale (NRS), and the modified dental anxiety score (MDAS). Hemodynamic parameters were recorded in 5 periods as T0 defined as 5 minutes before the injection (baseline), T1 defined as immediately after the injection along with NRS. The T2, T3, and T4 were defined as 5, 10, and 15 minutes after the injection, respectively. Comparing mean hemodynamic parameters at different times to baseline showed that almost all parameters changed to peak level immediately after injection (T1) except pulse rate of 4% articaine with 1 : 200,000 epinephrine reached the peak at T2 then gradually decreased to baseline within 15 minutes. In conclusion, comparison of blood pressure and pulse rate in hypertensive patient following the injection of 4% articaine in both groups had no statistically significant difference in hemodynamic changes.

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1.
Thachaya Satavuthi, Thitiporn Kangwannarongkul, Nattawut Supachawaroj, Chanaporn Phaengdee, Piyagorn Arunrukthavon, Sujari Jumpawong, et al. Comparison of blood pressure and pulse rate in hypertensive patient following the injection of 4% articaine with epinephrine 1 : 100,000 and 1 : 200,000. Thai J. Oral Maxillofac. Surg. [Internet]. 2026 Aug. 27 [cited 2026 Nov. 2];38(2):125-3. Available from: https://he02.tci-thaijo.org/index.php/thaijoms/article/view/284460
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