This is the second issue of volume 45. In this issue, we hope that you, our beloved reader, would benefit from reading our interesting studies including the study regarding diagnostic performances of different cut-off points of urine protein to creatinine ratio for detection of significant proteinuria in suspected preeclamptic women. Another study is about the intervention to enhance adherence of the continuous positive airway pressure machine users using the cloud-based tracking system with telemonitoring. The last but not least study in this issue is the use of topical herbal medicine to relieve pruritus in patients with end-stage renal disease. We do hope you found these interesting as always.