Factors Associated with Multi‐Drug Resistant Infections among Patients of Udonthani Cancer Hospital

Abstract

The purpose of this study was to investigate factors associated with multiple antimicrobial resistances in cancer patients at Udon Thani Cancer Hospital. Data were collected from assessing 158 files of medical records of infected cancer patients who were hospitalized at Udon Thani Cancer Hospital from 1 October 2013 to 30 September 2016. The records involved results of laboratory tests, microbiology and patient records. Collected data were then analyzed using descriptive statistics including mean, standard deviation, range, percentage and chi-square test as inferential statistics. Finding revealed that majority of patients who experienced multidrug resistance were males, aged 45 to 60 years old, skinny shape with smoking and drinking habits. They were diagnosed with the underlying condition of diabetes and high blood pressure. Those who were prescribed steroids as part of treatment for illness included cancer patients such as intestinal cancer, cervical cancer, Cholangiocarcinoma, urinary tract infection (UTIs), respiratory tract infection (UTIs), and skin and tissue infections. Communities were recorded as sources of infection. Bacteria resistant were noted as Escherichia coli, Klebsiella Pneumonia and Staphylococcus aureus. Antibiotics resistant were presented as Ceftazidime, Cefotaxime and Ceftriaxone. Resistant patients were prescribed 2 – 4 kinds of antibiotics for treatments. This study concluded that risk factors associated with multidrug resistant bacteria include sex, age, cancer, organs of infections, underlying diseases, source of infectious, duration of hospitalization and smoking and drinking habits.