Predictive Factors of Necrotizing Fasciitis Severity in Patients Admitted to the Surgical Ward at Udon Thani Hospital
Keywords:
Necrotizing Fasciitis, Associated Factors, Disease SeverityAbstract
Introduction: Necrotizing fasciitis is a severe infectious condition that spreads rapidly and carries a high mortality rate. It is therefore necessary to study the factors associated with disease severity in order to assist with risk assessment and guide appropriate treatment planning.
Research Objectives: To study the factors associated with and predictive of the severity of necrotizing fasciitis in patients admitted for hospital treatment.
Research Methodology: This was a cross-sectional study. The sample consisted of 64 patients diagnosed with necrotizing fasciitis admitted to the male and female surgical wards at Udon Thani Hospital. Data were collected using questionnaires covering general patient information, a disease severity assessment tool, a knowledge assessment, and a self-care behavior questionnaire for necrotizing fasciitis patients. Data were analyzed using descriptive statistics and multiple logistic regression analysis.
Results: Variables significantly associated with and predictive of necrotizing fasciitis severity (P < 0.05) were: marital status (OR = 0.08, 95% CI: 0.01–0.52, p = 0.01), occupation (OR = 7.35, 7.81, 95% CI: 0.01–0.44, p = 0.01), cause of infection (OR = 11.46, 95% CI: 1.99–65.89, p = 0.01), knowledge about necrotizing fasciitis (OR = 13.85, 95% CI: 2.42–79.34, p = 0.01), and patient self-care behavior (OR = 3.94, 95% CI: 1.05–14.81, p = 0.04).
Conclusion: Assessing the severity of necrotizing fasciitis is important for use as information in planning patient care to prevent serious complications.
Implications: Further research should be conducted in larger sample groups to confirm long-term effectiveness.
References
Moet GJ, Jones RN, Biedenbach DJ, Stilwell MG, Fritsche TR. Contemporary causes of skin and soft tissue infections in North America, Latin America, and Europe: report from the SENTRY Antimicrobial Surveillance Program (1998–2004). Diagn Microbiol Infect Dis. 2007;57(1):7–13.
S. Tavitiya. Necrotizing fasciitis .[Internet]. 2025 June 13 Available from: https://www.pidst.or.th/A766.html
Phunlap C. Factors Associated with Death in Patients with Necrotizing Fasciitis at Department of Surgery, Roi Et Hospital. Srinagarind Med J 2021; 36(4):389-400.
Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014;59:e10–52.
Jenkins TC, Knepper BC, McCollister BD, et al. Failure of outpatient antibiotics among patients hospitalized for acute bacterial skin infections: what is the clinical relevance? Am J Emerg Med. 2016;34(6):957–62.
Somkhuna S., Phothinakkha R. Effectiveness of the Discharge Planning Program on Knowledge and Self-Care Behavior of Patients with Necrotizing Fasciitis. J Environ Community Health. 2023;9(1):463-71.
Intharasukphon K., Clinical Feature of Necrotizing Fasciitis patientsin Phaholpolpayuhasena Hospital. Region 4-5 Medical J.2017;36(3):168-75.
Thodphetch M, et al. A comparison of scoring systems for predicting mortality and sepsis in the emergency department patients with a suspected infection. Clin Exp Emerg Med. 2021;8(4):289.
Khamnuan P, Chongruksut W, et al. Necrotizing fasciitis: risk factors of mortality. Risk Manag Healthc Policy. 2015;8:1–7.
Teeratakulpisarn P. Necrotizing Fasciitis. Srinagarind Med J 2022; 37(3):303-12.
Kritnikornkul A.,Fanmoon P.and Jearwattanakanok k. Prediction score for in-hospital mortality among patients with necrotizing fasciitis: derivation and internal validation. J Nakornping Hospital.2023;14(2):342–54.
Hakkarainen TW, Kopari NM, Pham TN, Evans HL. Necrotizing soft tissue infections: review and current concepts in treatment, systems of care, and outcomes. Curr Probl Surg. 2014;51(8):344–62.
Das DK, Baker MG, Venugopal K. Risk factors, microbiological findings and outcomes of necrotizing fasciitis in New Zealand: a retrospective chart review. BMC Infect Dis. 2012;12:348.
Madsen MB, Skrede S, Perner A, et al. Patient’s characteristics and outcomes in necrotising soft-tissue infections: results from a Scandinavian, multicentre, prospective cohort study. Intensive Care Med. 2019;45:1241–51.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 วิทยาลัยพยาบาลบรมราชชนนีอุดรธานี

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
