A Predictive Model of Human Papillomavirus Vaccination Intention Among Young Women in Southern Thailand

Authors

  • Sukmadewi Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Thailand.
  • Sopen Chunuan RN, PhD, Associate Professor, Faculty of Nursing, Prince of Songkla University, Thailand.
  • Kamonthip Wiwattanawongsa PhD, Assistant Professor, Department of Clinical Pharmacy, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Thailand.
  • Aris Widayati PhD, Associate Professor, Department of Social, Behavioral, and Administrative Pharmacy, Faculty of Pharmacy, Sanata Dharma University, Yogyakarta, Indonesia.

Keywords:

College Women, Human papillomavirus, Human papilloma vaccine, Health Belief Model, Structural equation modeling, Theory of Planned Behavior, Thailand

Abstract

              Cervical cancer is still a major public health problem worldwide. However, the uptake of human papillomavirus vaccine remains low among college women in Thailand. A cross-sectional and structural equation model to predict the intention to obtain human papillomavirus vaccine by young college women in Thailand was developed and tested. Data were collected from 191 college women aged 18-26 from the non-health sciences who were enrolled in two universities in Southern Thailand. Data collection involved the use of a structured questionnaire, which included demographic information, human papillomavirus and vaccine awareness, attitudes, subjective norms, perceived behavioral control, perceived susceptibility, perceived effectiveness, cost, knowledge of HPV and cervical cancer, and intention to obtain HPV vaccination. The data were analyzed using descriptive statistics and structural equation modeling.

            The results showed that, in the modified Model of Human Papillomavirus Vaccination Intention among Young Women, attitudes, subjective norms, perceived behavioral control, and perceived susceptibility of HPV-related disease all had significant and direct effects on the intention to obtain HPV vaccine, and able to explain 38% of the variance. Attitude was found to be the mediator of knowledge about human papillomavirus and cervical cancer, subjective norms, perceived behavioral control and the perceived effectiveness toward the intention to obtain human papillomavirus vaccination. Thus, nurses should take the initiative and make college women more familiar with the human papillomavirus vaccine, promote positive attitudes towards human papillomavirus vaccination and empower college women to take control of their vaccination decision-making.

References

Jin J. HPV infection and cancer. JAMA. 2018; 319 (10): 1058. doi: 10.1001/jama.2018.0687.

Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018; 68 (6):394-424. doi: 10.3322/caac.21492.

WHO. Human papillomavirus (HPV) and cervical cancer [Internet]. Geneva (CH): WHO; [updated 2019 Jan 24; cited 2019 Mar 1]. Available from: https://www.who. int/news-room/fact-sheets/detail/human-papillomavirus- (hpv)-and-cervical-cancer

Bruni L, Barrionuevo-R L, Albero G, Serrano B, Mena M, Gómez D, et al. Human papillomavirus and related diseases in Thailand. Barcelona (Spain): ICO/IARC Information Centre on HPV and Cancer (HPV Information Centre); 2018. 306 p. Report No.: Summary Report 17 June. Contract No.: HEALTH-F3-2010-242061, HEALTH-F2-2011-282562, HPV AHEAD. Supported by the European Commission (7th Framework Programme).

Suthipintawong C, Siriaunkgul S, Tungsinmunkong K, Pientong C, Ekalaksananan T, Karalak A, et al. Human papilloma virus prevalence, genotype distribution, and pattern of infection in Thai women. Asian Pac J Cancer P. 2011; 12(4):853-6.

Asianmedicstore [Internet]. [place unknown] : [publisher unknown]; [ cited 2019 June 21]. Available from: https:// asianmedicstore.com/dmsc-reports-that-human-papillo mavirus-hpv-vaccines-submitted-for-registration-inthailand-have-met-the-requirements/

Klinsupa W, Pensuk P, Thongluan J, Boonsut S, Tragoolpua R, Yoocharoen P, et al. O16.3 HPV vaccine introduction in Thailand. Sex Transm Infect. 2015; 91(Suppl 2):A61. doi: 10.1136/sextrans-2015-052270.167.

Clinic TT. Available vaccines in our clinic and price list Bangkok [Internet]: Bangkok: Hospital for tropical disease, Faculty of Tropical Medicine, Mahidol University; [cited 2020 Apr 25]. Available from: https://www.thaitravel clinic.com/cost.html

Lehtinen M, Lagheden C, Luostarinen T, Eriksson T, Apter D, Harjula K, et al. Ten-year follow-up of human papillomavirus vaccine efficacy against the most stringent cervical neoplasia end-point-registry-based follow-up of three cohorts from randomized trials. BMJ Open. 2017; 7 (8):e015867. doi: 10.1136/bmjopen-2017-015867.

Gee J, Weinbaum C, Sukumaran L, Markowitz LE. Quadrivalent HPV vaccine safety review and safety monitoring plans for nine-valent HPV vaccine in the United States. Hum Vaccin Immunother. 2016; 12(6):1406-17. doi: 10.1080/ 21645515.2016.1168952.

World Health Organization. Vaccination and trust [Internet]. Copenhagen: WHO Regional Office for Europe; 2013 [cited 2018 April 28]. 50 p. Available from: https://www. euro.who.int/__data/assets/pdf_file/0004/329647/ Vaccines-and-trust.PDF

CDC. HPV Vaccine information for young women 2016 [Internet]. [place unknown]: WHO; [cited 2020 Jul 5]. Available from: https://www.cdc.gov/std/hpv/stdfacthpv-vaccine-young-women.htm

Meites E, Szilagyi PG, Chesson HW, Unger ER, Romero JR, Markowitz LE. Human papillomavirus vaccination for adults: updated recommendations of the advisory committee on immunization practices. MMWR-Morbid Mortal W. 2019; 68 (32):698–702. doi: 10.15585/mmwr.mm6832a3.

Ajzen I. The theory of planned behavior. Organ Behav Hum Dec. 1991, 50(2):179-211. doi: 10.1016/0749- 5978(91)90020-T.

Steel RP, Ovalle NK. A review and meta-analysis of research on the relationship between behavioral intentions and employee turnover. J of Appl Psych. 1984; 69(4):673-86. doi: 10.1037/0021-9010.69.4.673.

Juntasopeepun P, Davidson PM, Suwan N, Phianmongkhol Y, Srisomboon J. Human papillomavirus vaccination intention among young women in Thailand. Asian Pac J Cancer P. 2011; 12(12):3213-9.

Ratanasiripong NT, Sri-Umporn S, Kathalae D, Hanklang S, Ratanasiripong P. Human papillomavirus (HPV) vaccination and factors related to intention to obtain the vaccine among young college women in Thailand. J Health Res. 2018; 32(2):142-51.

Bennett KK, Buchanan JA, Adams AD. Social-cognitive predictors of intention to vaccinate against the human papillomavirus in college-age women. J Soc Psychol. 2012; 152(4):480-92. doi: 10.1080/00224545. 2011.639408.

Gainforth HL, Cao W, Latimer-Cheung AE. Determinants of human papillomavirus (HPV) vaccination intent among three Canadian target groups. J Cancer Educ. 2012; 27(4): 717-24. doi: 10.1007/s13187-012-0389-1.

Krawczyk AL, Perez S, Lau E, Holcroft CA, Amsel R, Knäuper B, et al. Human papillomavirus vaccination intentions and uptake in college women. Health Psychol. 2012; 31(5):685-93. doi: 10.1037/a0027012.

Patel DA, Zochowski M, Peterman S, Dempsey AF, Ernst S, Dalton VK. Human papillomavirus vaccine intent and uptake among female college students. J Am Coll Health. 2012; 60(2):151-61. doi: 10.1080/07448481.2011. 580028.

You D, Han L, Li L, Hu J, D. Zimet G, Alias H, et al. Human papillomavirus (HPV) vaccine uptake and the willingness to receive the HPV vaccination among female college students in China: a multicenter study. Vaccines. 2020; 8(1):31. doi: 10.3390/vaccines8010031.

Shojaei S, Farhadloo R, Aein A, Vahedian M. Effects of the health belief model (HBM)-based educational program on the nutritional knowledge and behaviors of CABG patients. J Tehran Heart Cent. 2016, 11(4):181-6.

Rogers RW. A protection motivation theory of fear appeals and attitude change1. J Psychol. 1975; 91(1):93-114. doi: 10.1080/00223980.1975.9915803.

Armitage CJ, Conner M. Efficacy of the theory of planned behaviour: A meta-analytic review. Br J of Soc Psychol. 2001; 40 (4):471-499. doi: 10.1348/014466601164939.

Ajzen I. Theory of planned behavior with background factors 2017 [Internet]. [place unknown] : [publisher unknown]; [cited 2018 April 18]. Available from http:// people.umass.edu/aizen/tpb.background.html

Meites E, Kempe A, Markowitz LE. Use of a 2-dose schedule for human papillomavirus vaccination - updated recommendations of the advisory committee on immunization practices. Morbidity and Mortality Weekly Report (MMWR). Department of Health & Human Services (US). Updated 2016.

Kyriazos TA. Applied psychometrics: sample size and sample power considerations in factor analysis (EFA,CFA) and SEM in general. Psychology. 2018; 9:2207-30. doi: 10.4236/psych.2018.98126.

World Health Organization. Process of translation and adaptation of instruments [Internet]. Geneva (CH): WHO; [cited 2018 Mei 2]. Available from: http://www.who. int/substance_abuse/research_tools/translation/en/

Ratanasiripong NT. What college women know, think, and do about human papillomavirus (HPV) and HPV vaccine [dissertation]. University of Missouri; 2012. 144 p.

Wang MC, Chou CY, Ma MC, Hsu YY. Parental intention regarding the administration of the HPV vaccine for adolescent daughters in Taiwan. Women’s Health. 2016; 56(4):361- 75. doi: 10.1080/03630242.2015.1101740.

Gerend MA, Shepherd JE. Predicting human papillomavirus vaccine uptake in young adult women: comparing the health belief model and theory of planned behavior. Ann Behav Med. 2012; 44(2):171-80. doi: 10.1007/s12160- 012-9366-5.

Donadiki EM, Jimenez-Garcia R, Hernandez-Barrera V, Sourtzi P, Carrasco-Garrido P, de Andres AL, et al. Health belief model applied to non-compliance with HPV vaccine among female university students. Public Health. 2014; 128 (3):268-73. doi: 10.1016/j.puhe.2013.12.004.

Hayton JC, Allen DG, Scarpello V. Factor retention decisions in exploratory factor analysis: a tutorial on parallel analysis. Organ Res Methods. 2004; 7(2):191-205. doi: 10.1177/1094428104263675.

Kline RB. Principles and practice of stuctural equation modeling. 4th edition. New York: Guilford Press; 2016.

Hair JF, Risher JJ, Sarstedt M, Ringle CM. When to use and how to report the results of PLS-SEM. Europ Bus Rev. 2019; 31(1):2-24. doi: 10.1108/EBR-11-2018-0203.

Sung MH, Sung MH. Factors influencing human papillomavirus vaccination intention in female high school students: application of planned behavior theory. Korean J Women Health Nurs. 2018; 24(1):71-9. doi: 10. 4069/kjwhn.2018.24.1.71.

Britt RK, Hatten KN, Chappuis SO. Perceived behavioral control, intention to get vaccinated, and usage of online information about the human papillomavirus vaccine. Health Psychol Behav Med. 2014; 2(1):52-65. doi: 10.1080/21642850.2013.869175.

Downloads

Published

2021-03-27

How to Cite

1.
Sukmadewi, Chunuan S, Wiwattanawongsa K, Widayati A. A Predictive Model of Human Papillomavirus Vaccination Intention Among Young Women in Southern Thailand. PRIJNR [Internet]. 2021 Mar. 27 [cited 2024 Dec. 22];25(2):298-311. Available from: https://he02.tci-thaijo.org/index.php/PRIJNR/article/view/242206

Issue

Vol. 25 No. 2 (2021): April-June, 2021

Section

Original paper

License

Copyright: The Pacific Rim International Journal of Nursing Research, Thailand Nursing & Midwifery Council has exclusive rights to publish, reproduce and distribute the manuscript and all contents therein.