Predictors of Medication Adherence among Older Adults at an Elderly University in Pathum Thani Province
Keywords:
Predictive factors, Medication adherence behaviors, Older adults, Non-communicable diseases, social supportAbstract
This predictive correlational study aimed to: 1) examine medication adherence levels among older adults with non-communicable diseases (NCDs) and 2) identify predictors of medication adherence, including knowledge of disease and medication use, health beliefs, self-efficacy, and social support. The sample consisted of older adults enrolled in an elderly university in Lam Luk Ka District, Pathum Thani Province, selected through simple random sampling. Research instruments included questionnaires on personal characteristics, knowledge of disease and medication use, health beliefs, self-efficacy, social support, and medication adherence. Data were analyzed using descriptive statistics and stepwise multiple regression analysis. The results revealed that:
1. participants demonstrated a good level of medication adherence (M= 43.50, SD= 2.70).
2. Knowledge of diseases and medication, health beliefs, and self-efficacy were significant predictors of medication adherence behaviors among older adults patients with non-communicable diseases (β= 0.426, β= 0.217, and β= 0.216, respectively; p < .001), followed by social support (β= 0.119, p < .05). Collectively, these four factors accounted for 64.0% of the variance in medication adherence behaviors (Adjusted $R^2$ = .630, p < .001).
These findings suggest that developing interventions to enhance medication adherence should focus on improving patient knowledge, promoting health beliefs, boosting self-efficacy, and strengthening social support systems.
References
Alani Abdallah, S., Ahmad, M., & Al-Daken, L. I. (2024). Evaluating the health belief model in predicting medication adherence among patients with chronic diseases: A systematic review. Journal of Health Psychology, 29(4), 512–525. https://doi.org/10.1177/13591053231180000
American Diabetes Association. (2023). Pharmacologic approaches to glycemic treatment: Standards of medical care in diabetes—2023. Diabetes Care, 46(Suppl. 1), S140–S157. https://doi.org/10.2337/dc23-S009
Bandura, A. (1977). Social learning theory. Prentice-Hall.
Brown, M. T., & Bussell, J. K. (2011). Medication adherence: WHO cares? Mayo Clinic Proceedings, 86(4), 304–314. https://doi.org/10.4065/mcp.2010.0575
Champion, V. L., & Skinner, C. S. (2008). The health belief model. In K. Glanz, B. K. Rimer, & K. Viswanath (Eds.), Health behavior and health education: Theory, research, and practice (4th ed., pp. 45–65). Jossey-Bass.
Cutler, R. L., Fernandez-Llimos, F., Frommer, M., Benrimoj, C., & Garcia-Cardenas, V. (2018). Economic impact of medication non-adherence by disease groups: A systematic review. BMJ Open, 8(1), e016982. https://doi.org/10.1136/bmjopen-2017-016982
Department of Disease Control. (2024). Annual epidemiological surveillance report 2024. Ministry of Public Health. (in Thai)
DiMatteo, M. R. (2004). Social support and patient adherence to medical treatment: A meta-analysis. Health Psychology, 23(2), 207–218. https://doi.org/10.1037/0278-6133.23.2.207
Fernandez, S., Chaplin, W., Schoenthaler, A. M., & Ogedegbe, G. (2008). Revision and validation of the medication adherence self-efficacy scale (MASES) in hypertensive African Americans. Journal of Behavioral Medicine, 31(6), 453–462. https://doi.org/10.1007/s10865-008-9170-7
Gallant, M. P. (2003). The influence of social support on chronic illness self-management: A review and directions for research. Health Education & Behavior, 30(2), 170–195. https://doi.org/10.1177/1090198102250303
Gast, A., & Mathes, T. (2019). Medication adherence influencing factors-An (updated) overview of systematic reviews. Systematic Reviews, 8(1), 112. https://doi.org/10.1186/s13643-019-1014-8
Kini, V., & Ho, P. M. (2018). Interventions to improve medication adherence: A review. JAMA, 320(23), 2461–2473. https://doi.org/10.1001/jama.2018.19271
Komkhuntod, C. (2011). Factors predicting medication adherence behaviors among older adults with hypertension [Master’s thesis, Mahidol University]. (in Thai)
National Economic and Social Development Council. (2023). Population projections for Thailand 2010–2040 (Revised edition). (in Thai)
Osterberg, L., & Blaschke, T. (2005). Adherence to medication. New England Journal of Medicine, 353(5), 487–497. https://doi.org/10.1056/NEJMra050100
Ploylearmsang, C., Kongkaew, C., & Chaiyakunapruk, N. (2021). Medication adherence and quality of life among elderly patients with chronic diseases: A cross-sectional study in community settings. International Journal of Clinical Pharmacy, 43(2), 456–465. https://doi.org/10.1007/s11096-020-01165-y
Rosenstock, I. M., Strecher, V. J., & Becker, M. H. (1988). Social learning theory and the health belief model. Health Education Quarterly, 15(2), 175–183. https://doi.org/10.1177/109019818801500203
Schoenthaler, A., Chaplin, W. F., Allegrante, J. P., Fernandez, S., Diaz-Gloster, M., Tobin, J. N., & Ogedegbe, G. (2009). Provider communication effects medication adherence in hypertensive African Americans. Patient Education and Counseling, 75(2), 185–191. https://doi.org/10.1016/j.pec.2008.09.018
Thuy, L. T., Monkong, S., Pookboonmee, R., Leelacharas, S., & Viwatwongkasem, C. (2020). Factors explaining medication adherence of older adults with hypertension: A cross-sectional study. Pacific Rim International Journal of Nursing Research, 24(3), 306–320.
Vatcharavongvan, P., & Uttaranchal, S. (2017). Adherence to antihypertensive medications among patients in a primary care setting in Thailand. Journal of Primary Care & Community Health, 8(4), 314–319. https://doi.org/10.1177/2150131917724240
World Health Organization. (2024). Noncommunicable diseases fact sheet. https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases
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