Polyarteritis nodosa as a presenting symptom of Behçet's disease

Authors

  • Ittipon Tubtieng Ramathibodi hospital, mahidol university
  • Kumutnart Chanprapaph DIVISION OF DERMATOLOGY, DEPARTMENT OF MEDICINE, FACULTY OF MEDICINE, RAMATHIBODI HOSPITAL, MAHIDOL UNIVERSITY, BANGKOK, THAILAND.

Keywords:

Behçet's disease, Polyarteritis nodosa

Abstract

A 30-year-old male with fever, multiple subcutaneous nodules on upper and lower extremities. He had history of recurrent oral ulcers for 2 times a year. The skin biopsy on the leg was done at the lesion and showed necrotizing vasculitis of the medium-sized vessels. He was diagnosed with polyarteritis nodosa (PAN) due to weight loss, testicular pain and biopsy of medium-sized artery containing neutrophils. Because of clinical suspected Behçet's disease, the pathergy test was done and showed positive histology. Therefore, the final diagnosis is PAN in accompany with Behçet's disease. These two conditions have been reported very rarely in the literature. Most reported cases had a chronic relapsing course and PAN is considered as a bad prognostic factor of Behçet's disease.

References

Yazici H, Tüzün Y, Pazarli H, et al. Influence of age of onset and patient’s sex on the prevalence and severity of manifestations of Behçet’s syndrome. Ann Rheum Dis 1984; 43: 783–9.

Mendes D, Correia M, Barbedo M, et al. Behçet’s disease a contemporary review. J Autoimmun 32:178–188.

Zeidan MJ, Saadoun D, Garrido M, et al. Behçet's disease physiopathology: a contemporary review. Auto Immun Highlights 2016; 7: 4.

Magro CM, Crowson AN. Cutaneous manifestations of Behçet's disease. Int J Dermatol 1995: 34; 159-65.

King R, Crowson AN, Murray E, Magro CM. Acral purpuric papulonodular lesions as a manifestation of Behçet's disease. Int J Dermatol 1995: 34; 190-2.

Tursen U, Gurler A, Boyvat A. Evaluation of clinical findings according to sex in 2313 Turkish patients with Behçet’s disease. Int J Dermatol 2003; 42: 346–51.

Evereklioglu C. Current concepts in the etiology and treatment of Behçet disease. Sury Ophthalmol 2005; 50: 297-350.

Davatchi F, Shahram F, Chams-Davatchi C, et al. Behcet's disease: from east to west. Clin Rheumatol 2010; 29: 823–33.

Liao YH, Hsiao GH, Hsiao CH. Behçet's disease with cutaneous changes resembling polyarteritis nodosa. Br J Dermatol 1999; 140: 368-9.

Serra-Guillén C, Llombart B, Alfaro-Rubio A, et al. [Behçet's disease and periarteritis nodosa with cutaneous lesions]. Actas Dermosifiliogr 2007; 98: 217-8.

Lightfoot RW Jr, Michel BA, Bloch DA, et al. The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa. Arthritis Rheum 1990; 33: 1088-93.

Hatemi G, Christensen R, Bang D, et al. 2018 update of the EULAR recommendations for the management of Behçet’s syndrome. Ann Rheum Dis 2018; 77: 808-18.

De Virgilio A, Greco A, Magliulo G, et al. Polyarteritis nodosa: A contemporary overview. Autoimmun Rev 2016; 15: 564-70.

Downloads

Published

2019-10-01

How to Cite

Tubtieng, I., & Chanprapaph, K. (2019). Polyarteritis nodosa as a presenting symptom of Behçet’s disease. Thai Journal of Dermatology, 35(3), 144–148. Retrieved from https://he02.tci-thaijo.org/index.php/TJD/article/view/161598

Issue

Vol. 35 No. 3 (2019): July - September

Section

Case Report

License

เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ

บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น